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RIFM fragrance ingredient safety assessment, cadinene, CAS Registry Number 29350-73-0

RIFM fragrance ingredient safety assessment, nonanal, 5-ethyl-2-methyl-, CAS Registry Number 68141-14-0

RIFM fragrance ingredient safety assessment, 5-hydroxy-7-decenoic acid δ-lactone, CAS Registry Number 25524-95-2

The existing information supports the use of this material as described in this safety assessment. 5-Hydroxy-7-decenoic acid δ-lactone was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across material tetrahydro-6-(3-pentenyl)-2H-pyran-2-one (CAS #

RIFM fragrance ingredient safety assessment, 3-methyl-5-phenylpent-2-enenitrile, CAS registry number 93893-89-1

RIFM fragrance ingredient safety assessment, 2,10-Tetradecadienenitrile, (2E,10Z)-, CAS Registry Number 1958026-97-5

RIFM fragrance ingredient safety assessment, p-mentha-1,3-diene, CAS Registry Number 99-86-5

RIFM fragrance ingredient safety assessment, dl-limonene (racemic), CAS Registry Number 138-86-3

RIFM fragrance ingredient safety assessment, methyl N-methylanthranilate, CAS Registry Number 85-91-6

RIFM fragrance ingredient safety assessment, menthol, CAS Registry Number 89-78-1

RIFM fragrance ingredient safety assessment, citronelloxyacetaldehyde, CAS Registry Number 7492-67-3

RIFM fragrance ingredient safety assessment, tetrahydro-4-methyl-2-propyl-2H-pyran-4-yl acetate, CAS Registry Number 131766-73-9

Update to RIFM fragrance ingredient safety assessment, fenchyl alcohol, CAS Registry Number 1632-73-1

RIFM fragrance ingredient safety assessment, 2-undecenenitrile, CAS Registry Number 22629-48-7

RIFM fragrance ingredient safety assessment, isoeugenyl ethyl ether, CAS Registry Number 7784-67-0

Update to RIFM fragrance ingredient safety assessment, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol, CAS Registry Number 67801-20-1

RIFM fragrance ingredient safety assessment, trans-2-nonenal, CAS Registry Number 18829-56-6

RIFM fragrance ingredient safety assessment, octyl isobutyrate, CAS Registry Number 109-15-9

The existing information supports the use of this material as described in this safety assessment. Octyl isobutyrate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog hexyl isobutyrate (CAS # 2349-07-7) show that octyl isobutyrate is

RIFM fragrance ingredient safety assessment, citronellyl formate, CAS Registry number 105-85-1

RIFM fragrance ingredient safety assessment, 3-methyl-1-cyclopentadecanone, CAS Registry Number 541-91-3

RIFM fragrance ingredient safety assessment, 2-cyclohexylpropanal, CAS Registry Number 2109-22-0