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A three bit second order delta sigma modulator for audio applications implemented in 130nm CMOS technology is presented. The modulator features two integrators, a flash quantizer and two current steering DACs. In order to minimize the effect of delays in the DACs, excessive loop delay (ELD) compensation is utilized. Using an oversampling ratio (OSR) of 80, the design consumes 2.8mW and achieves a
In this paper we present an audio synthesizer that creates audio signals, intended to be reproduced as sound by a loudspeaker. This paper details the design, implementation and verification of an analog, subtractive audio synthesizer. The synthesizer produces a variety of waveforms spanning approximately 3 octaves. The frequency is controlled by an external voltage and the harmonic content is regu
The analysis of the trace graphs generated by dataflow program executions has been shown to be an effective tool for exploring and optimizing the design space of application programs on manycore/multicore platforms. In this work a new approach aiming at finding bounded buffer size configurations for implementations generated by dataflow programs is presented. The introduced method is based on an o
Collaborative filtering for recommender systems seeks to learn and predict user preferences for a collection of items by identifying similarities between users on the basis of their past interest or interaction with the items in question. In this work, we present a conjugate prior regularized extension of Hofmann's Gaussian emission probabilistic latent semantic analysis model, able to overcome th
The improvements in GPU hardware, including hardware-accelerated ray tracing, and the push for fully dynamic realistic-looking video games, has been driving more research in the use of ray tracing in real-time applications. The work described in this thesis covers multiple aspects such as optimisations, adapting existing offline methods to real-time constraints, and adding effects which were hard
We significantly strengthen and generalize the theorem lifting Nullstellensatz degree to monotone span program size by Pitassi and Robere (2018) so that it works for any gadget with high enough rank, in particular, for useful gadgets such as equality and greater-than. We apply our generalized theorem to solve three open problems: •We present the first result that demonstrates a separation in proof
One of the major open problems in complexity theory is proving super-logarithmic lower bounds on the depth of circuits (i.e., mathrm{P} nsubseteq text{NC}{1}). Karchmer, Raz, and Wigderson [13] suggested to approach this problem by proving that depth complexity behaves'as expected' with respect to the composition of functions f diamond g. They showed that the validity of this conjecture would impl
Reflective reconfigurable intelligent surface (RIS) technology is regarded as an innovative, cost- and power-effective solution that aims at influencing the wireless channel through controlled scattering. The technology can be realized by using metamaterials and/or resonant elements that scatter electromagnetic waves with a configurable phase shift. Most of the previous work on beamforming techniq
Objective: To facilitate a greater likelihood of favorable response to new disease-modifying therapies, recruitment of patients at an earlier stage of their disease into clinical trials may be an attractive strategy. Hence, there is a need to develop widely accepted classification criteria for early-stage knee osteoarthritis (OA). We have proposed a set of classification criteria for early-stage k
Low-Power Wide-Area Networks operating in the unlicensed bands are being deployed to connect a rapidly growing number of Internet-of-Things devices. While the unlicensed sub-GHz band offers favorable propagation for long-range connections, measurements show that the energy consumption of the nodes is still mostly dominated by the wireless transmission affecting their autonomy. We investigate the p
In this paper we present a technique that improves rendering performance for real-time ith ray in the presence of dynamic lights and objects. In particular we verify photon paths from the previous frame against dynamic objects in the current frame, and show how most photon paths are still valid. When using area lights, we use a data structure to store light distribution that tracks light paths all
Importance: Supplementing preterm infants with long-chain polyunsaturated fatty acids (LC-PUFA) has been inconsistent in reducing the severity and incidence of retinopathy of prematurity (ROP). Furthermore, few studies have measured the long-term serum lipid levels after supplementation. Objective: To assess whether ROP severity is associated with serum levels of LC-PUFA, especially docosahexaenoi
Spatially-coupled serially concatenated codes (SC-SCCS) are a class of turbo-like codes constructed by interconnecting a sequence of SCCS using a set of block permutors. At short block lengths, however, the bit-error-rate (BER) performance of SC-SCCS constructed by independent block permutors exhibits a high error floor. In this paper, we propose an alternative method for constructing SC-SCCS to m
Aims: Because evidence regarding risk stratification predicting prognosis of patients with heart failure (HF) decompensation attended in primary care is lacking, we developed and externally validated a model to forecast death/hospitalization during the first 30 days after an episode of decompensation. The predictive model is based on variables easily obtained in primary care settings. Methods and
Background: An anterior cruciate ligament (ACL) rupture results in an increased risk of developing knee osteoarthritis (OA) at an early age. Before clinical signs become apparent, the OA process has already been initiated. Therefore, it is important to look at the cascade of changes, such as the activity of cytokines and proteases, which might be associated with the later development of OA. Purpos
PURPOSE/OBJECTIVE(S): Studies of electron FLASH radiotherapy (FLASH-RT) in companion animals are being conducted at several institutions. High energy electron beams are generally suitable for treatment of superficial cancers, but of limited use for deep-seated tumors. In this case report, the feasibility of intracavitary electron FLASH-RT is demonstrated.MATERIALS/METHODS: A canine cancer patient
