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Specific targeting of antigen-presenting cells for immunotherapy

Immunotherapy, which involves strategies to activate, enhance or redirect immune responses to achieve long-lasting immunity, has the potential to play an important role in the treatment of a variety of diseases. This thesis, based on four original papers, highlights different approaches to modulate immune responses by specific targeting of antigen-presenting cells. The first two studies focuses o

Some Notes on Present European and Scandinavian Co-production Practices Through the Prism of ‘The Girl with the Dragon Tattoo’ (2009)

In a critique of the sometimes confusing ways in which the term transnational has been repeatedly used, Mette Hjort, in 2010 attempted to outline what she called a “typology of transnationalisms” in connection with contemporary audio-visual production (2009: 12–33). Hjort’s palpable purpose here is to more specifically illuminate and contextualize the increasingly more used concept of transnationa

Heat transfer and friction factor in a dimple-pin fin wedge duct with various dimple depth and converging angle

Purpose - The dimple is adopted into a pin fin wedge duct which is widely used in modern gas turbine vane cooling structure trailing edge region. The purpose of this paper is to study the effects of dimple depth and duct converging angle on the endwall heat transfer and friction factor in this pin fin wedge duct. Design/methodology/approach - The study is carried out by using the numerical simulat

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Public debt soared in the late-medieval Low Countries: towns borrowed considerable sums from creditors and often ended up defaulting on their financial obligations. The author uses a tax inquiry from 1514 to demonstrate that villages also managed to create funded debt, which they secured on the public body of the village. As a result, around 1500 the majority of the villages in Holland owed annuit

3D droplet sizing and 2D optical depth measurements in sprays using SLIPI based techniques

While imaging optically dense media such as atomizing sprays, the multiple light scattering induces image artifacts and blurring effects which limit visibility.Therefore, extracting quantitative spray information such as droplet size and concentration from qualitative images becomes very challenging. However, multiple scattering effects can be efficiently addressed by means of the SLIPI (Structure

The Tycho-Gaia Astrometric Solution

Gaia DR1 is based on the first 14 months of Gaia's observations. This is not long enough to reliably disentangle the parallax effect from proper motion. For most sources, therefore, only positions and magnitudes are given. Parallaxes and proper motions were nevertheless obtained for about two million of the brighter stars through the Tycho-Gaia astrometric solution (TGAS), combining the Gaia obser