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Measurements of optical properties of pig brain tissue in vitro using a novel compact device

In numerous medical and scientific fields, knowledge of the optical properties of tissues can be applied. Among many different ways of determining the optical properties of turbid media; integrating sphere measurements are widely used. However, this technique is associated with bulky equipment, complicated measuring techniques, interference compensation techniques, and inconvenient sample handling

Temperature-induced phase partitioning of peptides in water solutions of ethylene oxide and propylene oxide random copolymers

A thermoseparating random copolymer (Ucon 50-HB-5100) composed of (50%) ethylene oxide and (50%) propylene oxide has been used to form an aqueous two-phase system by heating the polymer-water solution above the cloud point of the copolymer. In the formed two-phase system a water rich top phase is in equilibrium with an aqueous polymer rich bottom phase. The partitioning of amino acids and peptides

Thermostable Xylanases from Rhodothermus marinus

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Det magnifika skådespelet av erupterande geysrar, varma, rykande källor av skilda slag samt kokande lerpölar är en uppseendeväckande syn. Dessa extrema miljöer av hög temperatur och mycket låga pH-värden verkar långt ifrån livsbejakande. Trots detta finns liv representerat i form av mikroorganismer som här har funnit sina ideala livsmAbstract Hot springs in Iceland can serve as sources of thermophilic, xylanolytic bacteria secreting very thermostable xylanolytic enzymes. The aerobic, thermophilic bacteria Rhodothermus marinus secretes multiple xylanases and xylosidases. One of the xylanases was purified to electrophoretic homogeneity and was characterized. The N-terminal sequence showed no homology with other xylanases. The p

Association of anionic surfactant and physisorbed branched brush layers probed by neutron and optical reflectometry.

Pre-adsorbed branched brush layers were formed on silica surfaces by adsorption of a diblock copolymer consisting of a linear cationic block and an uncharged bottle-brush block. The charge of the silica surface was found to affect the adsorption, with lower amounts of the cationic polyelectrolyte depositing on less charged silica. Cleaning under basic conditions rendered surfaces more negatively c

Continuous full filling capillary electrochromatography-electrospraying chromatographic nanoparticles

The influence of instrumental parameters affecting the ionization in continuous full filling capillary electrochromatography/electrospray ionization mass spectrometry (CFF-CEC/ESI-MS) was investigated. The investigated parameters were the BGE and sheath liquid ion strength and organic modifier content, the nebulizer gas pressure, and the concentration of nanoparticles in the BGE. It was found that

Immunochemical Staining of MT2-MMP Correlates Positively to Angiogenesis of Human Esophageal Cancer

Matrix metalloproteinases (MMPs) play an important role in the pathological processes of degradation of extracellular matrix and destruction of basement membrane, which leads to tumor invasion and metastasis. In the present study, we investigated membrane-type 2 MMP (MT2-MMP) expression pattern in esophageal cancer tissues collected from 103 patients, and explored MT2-MMP expression pattern in cor

The art of braking : post saccadic oscillations in the eye tracker signal decrease with increasing saccade size

Abstract in Undetermined Recent research has shown that the pupil signal from video-based eye trackers contains post saccadic oscillations (PSOs). These reflect pupil motion relative to the limbus (Nyström, Hooge, & Holmqvist, 2013). More knowledge about video-based eye tracker signals is essential to allow comparison between the findings obtained from modern systems, and those of older eye tr

Heart Rate Variability in Children With Fontan Circulation: Lateral Tunnel and Extracardiac Conduit

The technique in Fontan surgery has developed from the lateral tunnel (LT) toward the extracardiac conduit (EC) used to reduce long-term complications such as atrial arrhythmia and sinus node dysfunction. Heart rate variability (HRV) examines cardiac nervous activity controlling the sinus node. This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the

Ambulatory oxygen for treatment of exertional hypoxaemia in pulmonary fibrosis (PFOX trial) : A randomised controlled trial

Introduction Interstitial lung diseases are characterised by scarring of lung tissue that leads to reduced transfer of oxygen into the blood, decreased exercise capacity and premature death. Ambulatory oxygen therapy may be used to treat exertional oxyhaemoglobin desaturation, but there is little evidence to support its efficacy and there is wide variation in clinical practice. This study aims to

European agricultural policy requires a stronger performance framework to achieve the Sustainable Development Goals

Non-technical summary Agriculture provides many benefits to people, such as producing food and creating jobs in rural areas, but it can also have negative impacts on the environment. We analysed existing monitoring indicators for the European Union’s Common Agricultural Policy (CAP) to evaluate whether the CAP is effectively achieving multiple social and environmental goals. We found that the curr

Few Differences in the Externalizing and Criminal History of Young Violent Offenders With and Without Autism Spectrum Disorders

Autism spectrum disorders (ASDs) are known to be associated with an increased risk of aggression and challenging behavior. In this study, we have mapped the externalizing history of a nationally representative cohort of young violent offenders with ASD, compared with offenders without ASD. Two hundred and sixty-nine violent offenders were assessed for prevalence of ASD, and participated in a thoro

3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3

The galectins are a family of galactose-binding proteins playing key roles in inflammatory processes and cancer. However, they are structurally very closely related, and discovery of highly selective inhibitors is challenging. In this work, we report the design of novel inhibitors binding to a subsite unique to galectin-3, which confers both high selectivity and affinity towards galectin-3. Olefin

Computer-assisted instruction in emergency ophthalmological care

The use of computer-assisted instruction in medical education has increased steadily in the last decade with the availability of personal computers. Many computer-assisted instruction programs train the user to handle various forms of disease or injury. Our intent was to provide medical students with more experience in managing ophthalmological emergencies, and we therefore designed a computerized

The dual rod system of amphibians supports colour discrimination at the absolute visual threshold

The presence of two spectrally different kinds of rod photoreceptors in amphibians has been hypothesized to enable purely rod-based colour vision at very low light levels. The hypothesis has never been properly tested, so we performed three behavioural experiments at different light intensities with toads (Bufo) and frogs (Rana) to determine the thresholds for colour discrimination. The thresholds

The motives of foster parents, their family and work circumstances

In foster care research the focus is generally placed on the children, not on the parents who perform the foster care. In this article the focus is on foster parents of 10-11 year-old children. They were interviewed about their motives for becoming foster parents, which were linked to their family and work circumstances. Among the 21 foster families in the study, four different but equally frequen

The relationship of vocally disruptive behavior and previous personality in severely demented institutionalized patients.

The aim of this study was to explore the previous personalities of patients, their behavior during the course of the disease, and the relationship between the previous personality and vocally disruptive behavior of severely demented patients. Twenty-one severely demented patients identified as vocally disruptive and 19 severely demented control subjects who were matched for gender and ward were st

Ethanol impairs coagulation and fibrinolysis in whole blood: a study performed with rotational thromboelastometry.

The objective was to study the effects of ethanol on coagulation and fibrinolysis in whole blood. Blood samples from healthy volunteers were analyzed before and after in-vitro addition of ethanol in order to achieve ethanol concentrations of 0, 1, 2 and 4[per mille sign], respectively (0, 22, 44 and 88 mmol/l). Coagulation and fibrinolysis were then assessed using rotational thromboelastometry. We

An experimental and numerical study of the effect of friction in single dowel joints

The effect of friction between the dowel and the surrounding timber was studied for single dowel-type joints. The joints tested were divided into two groups of joints, where the surface of the dowels differed. For the first group, the dowels had a smooth surface and for the second group the dowels had a rough surface. A contactfree measurement technique was used in the experimental investigatio