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Impact of diabetes and glycemic status on ventricular-arterial coupling in the general population

BACKGROUND/AIMS: Ventricular-arterial coupling (VAC) plays a crucial role in cardiovascular physiology, affecting cardiac function and arterial properties for optimal organ perfusion. Considering that diabetes mellitus (DM) is a known risk factor for incident heart disease and vascular damage, this study aims to investigate whether changes in VAC due to DM occur earlier, even before the onset of c

Accessibility of eHealth before and during the COVID-19 pandemic among people with and people without impairment : repeated cross-sectional survey

Background: The adoption of eHealth accelerated during the COVID-19 pandemic. Inequalities in the adoption of eHealth during the COVID-19 pandemic have been reported, but there are few such studies among people with impairment. Objectives: This study aimed to investigate self-reported use and difficulty in the use of eHealth before the COVID-19 pandemic compared to during late social distancing re

Influence of feeding habit and duration on infant gut microbiome – a 6 month pilot study

While the importance of breastfeeding on the developing infant gut microbiota has been established, few studies have compared the effect of breastfeeding duration on infant gut microbiota development. In this pilot study, we included 23 infants, divided into 4 groups to compare the effect of breastfeeding duration for first 4 (BreastFed_4) or 8 weeks (BreastFed_8) compared to exclusive breast

Postoperative leukopenia after cytoreductive surgery and hypertherm intraperitoneal chemotherapy for colorectal carcinomatosis- causes and implication on outcomes in a population-based study

BACKGROUND: Leukocytes have been reported to have tumor stimulating effects in colorectal cancer, among other malignancies. In line with this, earlier research has shown improved disease-free survival in patients with postoperative neutropenia compared to non-neutropenic patients following cytoreductive surgery (CRS) and hypertherm intraperitoneal chemotherapy (HIPEC).AIM: To evaluate the impact o

Functional implications of the pH-trait distribution of the microbial community in a re-inoculation experiment across a pH gradient

We compared the influence of the microbial community composition and the environmental conditions for the functioning - microbial growth and respiration - and trait distribution - bacterial pH tolerance - of soil microorganisms across a pH gradient. Sterilised soil microcosms, including pH 4.1, 5.2, 6.7 and 8.3, with added plant litter were inoculated with unsterilized soil in a factorial design a

Adsorption of acetylene and hydrogen on Pd(111) : Formation of a well-ordered ethylidyne overlayer

The C2H2(+H)/Pd(111) system has been studied using high resolution core level spectroscopy and low energy electron diffraction (LEED). Two ordered phases were found when adsorbing C2H2 at 125 K, giving rise to a (2 × 2) and a (√3 × √3)R30° LEED pattern, respectively. When preadsorbing H at 110-150 K, the sticking probability of the C2H2 molecules is strongly reduced and only the (√3 × √3)R30° over

The structure of aggrecan fragments in human synovial fluid : Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

Synovial fluid was collected from patients with recent knee injury and from patients with early or late stage osteoarthritis. Chondroitin sulfate-substituted aggrecan fragments present in these fluids, and in normal bovine synovial fluid, were purified by cesium chloride gradient centrifugation, enzymically deglycosylated and fractionated by gel filtration on Superose-12. Each sample contained two

Differential effects of insulin-like growth factor-I on matrix and DNA synthesis in various regions and types of rabbit tendons

Tendon healing and integration of tendon grafts may be site or donor specific. To determine if differences exist in sensitivity to growth factors that have the potential to influence tendon repair, we compared the effect of recombinant human insulin-like growth factor-1 on various types of tendon segments. The dose response effects on proteoglycan, collagen, noncollagen protein, and DNA synthesis

Methodology for evaluation of hazards from solid waste and landfill generated leachate

Popular Abstract in Swedish Avfall har alltid uppkommit i alla samhällen i alla tider. Det vanligaste sättet att hand om det har varit att samla avfallet i soptippar (deponier) på mark som ansetts obrukbar, t.ex. i sankmarker utanför bebyggelsen. I takt med ökad konsumtion och produktion har också mängderna avfall ökat. Anledningen till att avfall och avfallshantering kommit alltmer i fokus i miljA methodology based on an analytical protocol for evaluation of hazards from landfill leachate and solid waste is described. A dynamic analytical protocol, the LAQUA protocol, including measurements of inorganic and water-quality parameters, polar and non-polar organic marker compounds, and toxicity, was constructed. An acute toxicity test, using the brackish water crustacean Artemia salina as tes

Polarization position angle standard stars : a reassessment of θ and its variability for seventeen stars based on a decade of observations

Observations of polarization position angle (θ) standards made from 2014 to 2023 with the High Precision Polarimetric Instrument (HIPPI) and other HIPPI-class polarimeters in both hemispheres are used to investigate their variability. Multiband data were first used to thoroughly recalibrate the instrument performance by bench-marking against carefully selected literature data. A novel co-ordinate

Combining Sentinel-2 Data and Risk Maps to Detect Trees Predisposed to and Attacked by European Spruce Bark Beetle : Remote Sensing

The European spruce bark beetle is a major disturbance agent in Norway spruce forests in Europe, and with a changing climate it is predicted that damage will increase. To prevent the bark beetle population buildup, and to limit further spread during outbreaks, it is crucial to detect attacked trees early. In this study, we utilize Sentinel-2 data in combination with a risk map, created from geodat

A sentinel-2 dataset for Uganda

Earth observation data provide useful information for the monitoring and management of vegetation- and land-related resources. The Framework for Operational Radiometric Correction for Environmental monitoring (FORCE) was used to download, process and composite Sentinel-2 data from 2018–2020 for Uganda. Over 16,500 Sentinel-2 data granules were downloaded and processed from top of the atmosphere re

Formation and temperature dependence of highly oxygenated organic molecules (HOMs) from δ3-carene ozonolysis

δ3-carene is a prominent monoterpene in the atmosphere, contributing significantly to secondary organic aerosol (SOA) formation. However, knowledge about δ3-carene oxidation pathways, particularly regarding their ability to form highly oxygenated organic molecules (HOMs), is still limited. In this study, we present HOM measurements during δ3-carene ozonolysis under various conditions in two simula

Birthweight and risk of chronic kidney disease after a type 2 diabetes diagnosis in the DD2 cohort

Aims/hypothesis: Low birthweight (LBW) is associated with younger age, less obesity and more hypertension among people recently diagnosed with type 2 diabetes, as well as increased cardiovascular morbidity and mortality risk. It is not known whether LBW is associated with an increased risk of incident chronic kidney disease (CKD) among people with a type 2 diabetes diagnosis. Methods: Original mid

Nurse-led atrial fibrillation clinics in primary health care : a review of the evidence

Background: Atrial fibrillation (AF) is the most common arrhythmia worldwide and the majority of AF patients are treated in primary care. In order to minimize hospitalizations and visits to emergency departments, nurse-led care was introduced in secondary care and primary health care (PHC). However, even though nurse-led care was initiated in PHC almost a decade ago, and ESC guidelines recommended

Reliability of data on percent consonants correct and its associated quality indicator in the Swedish cleft lip and palate registry

BACKGROUND: Data in national health care quality registries must be valid and reliable in order to enable open comparisons of results.AIM: To assess the reliability of data on percent consonants correct (PCC) and its associated quality indicator ≥86% correct consonants in the Swedish quality registry for patients born with cleft lip and palate (CLP) registry.METHODS: Six independent speech-languag

Performance Evaluation of Six Gridded Precipitation Products throughout Iran Using Ground Observations over the Last Two Decades (2000–2020)

Precipitation, as an important component of the Earth’s water cycle, plays a determinant role in various socio-economic practices. Consequently, having access to high-quality and reliable precipitation datasets is highly demanded. Although Gridded Precipitation Products (GPPs) have been widely employed in different applications, the lack of quantitative assessment of GPPs is a critical concern tha

Association of β-Amyloid Accumulation with Executive Function in Adults with Unimpaired Cognition

Background and Objectives The neuropathologic changes underlying Alzheimer disease (AD) start before overt cognitive symptoms arise, but it is not well-known how they relate to the first subtle cognitive changes. The objective for this study was to examine the independent associations of the AD hallmarks β-amyloid (Aβ), tau, and neurodegeneration with different cognitive domains in cognitively uni