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Purpose: To what extent active surveillance and deferred treatment for localized risk prostate cancer are used is unclear. We assessed the use of surveillance and of deferred treatment in a population based, nationwide cohort in Sweden. Materials and Methods: In the National Prostate Cancer Register of Sweden, with a 98% coverage vs the compulsory Swedish Cancer Registry, we identified 8,304 incid

Purpose: To evaluate the feasibility of oral cryotherapy (OC) in children and to investigate if OC reduces the incidence of severe oral mucositis (OM), oral pain, and opioid use in children undergoing hematopoietic stem cell transplantation (HSCT). Methods: Fifty-three children, 4–17 years old, scheduled for HSCT in Sweden were included and randomized to OC or control using a computer-generated li

Background: Many inborn errors of metabolism (IEMs) may present as sudden infant death (SID). Nowadays, increasing numbers of patients with IEMs are identified pre-symptomatically by population neonatal bloodspot screening (NBS) programmes. However, some patients escape early detection because their symptoms and signs start before NBS test results become available, they even die even before the sa

OBJECTIVES: Quantitative monitoring of human cytomegalovirus infections is helpful in determining appropriate antiviral management in patients who receive bone marrow transplants. We sought to design and evaluate a new cytomegalovirus capture hybrid polymerase chain reaction enzyme-linked immunosorbent assay (PCR-ELISA) in plasma and peripheral blood mononuclear cells to monitor cytomegalovirus in

AIM: We studied the frequency of Achilles tendon xanthoma (ATX) in patients with acute coronary syndrome (ACS). Furthermore, we investigated the differences in clinical findings between ACS patients with and without ATX.METHODS: Patients with ACS (n=335) were admitted to the coronary care unit of Nippon Medical School between July 2011 and December 2014. Informed consent for the measurement of Ach

Objectives: To use a population pharmacokinetic approach to define maximally effective meropenem dosing recommendations for treatment of Acinetobacter baumannii and Pseudomonas aeruginosa infections in a large cohort of patients with septic shock. Methods: Adult patients with septic shock and conserved renal function, treated with meropenem, were eligible for inclusion. Seven blood samples were co

YedY from Escherichia coli is a new member of the sulfite oxidase family of molybdenum cofactor (Moco)-containing oxidoreductases. We investigated the atomic structure of the molybdenum site in YedY by X-ray absorption spectroscopy, in comparison to human sulfite oxidase (hSO) and to a MoIV model complex. The K-edge energy was indicative of MoV in YedY, in agreement with X-and Q-band electron para

Energy expenditure, energy intake, body composition and selected biochemical analyses were studied in 14 males and 16 females with a mean age of 83 years (range 68-92) in geriatric long-stay wards. Energy expenditure was predicted from heart rate monitoring, and energy intake was assessed with a 4-day dietary record. Lean body mass (LBM), body fat (BF), and total body water (TBW) were estimated wi

Purpose: Bilateral adrenalectomy (BA) still plays an important role in the management of Cushing's disease (CD). Nelson’s syndrome (NS) is a severe complication of BA, but conflicting data on its prevalence and predicting factors have been reported. The aim of this study was to determine the prevalence of NS, and identify factors associated with its development. Data sources: Systematic literature

Background: In the laparoscopic Roux-en-Y gastric bypass procedure, the gastrojejunal stoma is constructed with either a circular (CSD) or a linear stapling device (LSD). The diameter of the stoma following stapling with the 21 mm CSD is expected to be approximately 12 mm (diameter of the anvil). Measuring the stoma diameter after linear stapling is a little more complex since the remaining openin

OBJECTIVES: Under physiological conditions the blood flow velocity waveform in the umbilical vein (UV) has an even non-pulsating pattern. Pulsations in the UV have been described in human fetuses exposed to chronic hypoxia and heart failure. Current techniques for fetal surveillance during labor and delivery involve a risk of both over- and underestimation of fetal hypoxia. We aimed to examine whe

Monitoring and regulation of fermentations is of a paramount industrial and academic importance in order to keep conditions optimal during the entire process. Established techniques employed today include HPLC and spectrophotometry, which both have the disadvantage that broth samples have to be drawn from the fermentor and that they often require sample pre-treatment. The objectives of this study

Aims In anticoagulation treatment with warfarin, the risk of thrombo-embolic events must be weighed against the risk of bleeding. Time in therapeutic range (TTR) is an important tool to assess the quality of anticoagulation treatment, and has been shown to correlate with less bleeding and thrombo-embolic complications. AuriculA, the Swedish national quality registry for atrial fibrillation and ant

Background: Despite a modest association between tobacco smoking and breast cancer risk reported by recent epidemiological studies, it is still equivocal whether smoking is causally related to breast cancer risk. Methods: We applied Mendelian randomisation (MR) to evaluate a potential causal effect of cigarette smoking on breast cancer risk. Both individual-level data as well as summary statistics

Aim: To assess available evidence on the use of rFVIIa in non-orthopaedic surgery including dental surgery in adult patients with congenital haemophilia with inhibitors (PWHI). Methods: A systematic literature search was performed according to a prespecified search string; prespecified criteria were used to select applicable studies including PWHI ≥18 years of age who underwent any non-orthopaedic

Sammanställning av alla skyddsområden inom LU Översikt täckning av skyddsombud inom alla skyddsområden • 6 st Huvudskyddområde saknar HSO och EHSO • 3 st Huvudskyddområde har ingen EHSO och väldigt många skyddsområden ( 20+) • 5 st huvudskyddsområden har fler än ett ordinarie SO inom samma skyddsområden • 4 st Huvudskyddområden behöver sannolikt delas in i fler skyddsområden Till de LU-gemensamma

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2025-12/Presentation%20CSK%20251203%20Sammanst%C3%A4llning%20skyddombud%20LU.pdf - 2026-05-24

Infant and Childhood Diet and Type 1 Diabetes Risk: Recent Advances and Prospects Jill M. Norris Published online: 20 July 2010 # Springer Science+Business Media, LLC 2010 Abstract Type 1 diabetes is a chronic autoimmune disease characterized by a preclinical period of autoimmunity. It is well accepted that both genetic and environmental factors contribute to disease risk. Given that type 1 diabet

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_15_norris_cdr_2010.pdf - 2026-05-24

Microsoft Word - RapportEnvariabelanalysVT22.docx Rapport om kursen i Envariabelanalys (MATA21) vårterminen 2022 Under vårterminen 2022 hade Envariabelanalyskursen 85 registrerade studenter varav 24 var omregistrerade. Det var totalt sett 43 studenter som klarade kursen, 38 av de nyregistrerade och 5 av de omregistrerade. Av de studenter som klarade kursen fick 19 stycken betyget VG. Alla studente

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2022/MATA21VT22.pdf - 2026-05-23