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Association of exome sequences with plasma C-reactive protein levels in >9000 participants.

C-reactive protein (CRP) concentration is a heritable systemic marker of inflammation that is associated with cardiovascular disease risk. Genome-wide association studies have identified CRP-associated common variants associated in ∼25 genes. Our aims were to apply exome sequencing to (1) assess whether the candidate loci contain rare coding variants associated with CRP levels and (2) perform an e

Gender Stereotypes and Armed Conflict - A Study of the Repercussions for International Justice

Väpnade konflikter är komplexa och mångfacetterade – män och kvinnors roller och nivå av inblandning varier avsevärt. Med detta i åtanke är det nödvändigt för internationell rätt och dess utövare att erbjuda ett reellt skydd, där ansvarsutkrävande och upprättelse erbjuds på lika villkor för alla oavsett kön. Risken är annars att vissa grupper osynliggörs. Sammanfattningsvis krävs det en nyanserad

När molnen hopar sig vid horisonten - En analys avseende EU:s regler om överföring av personuppgifter till tredjeländer och deras förenlighet med rätten till personlig integritet

Nu för tiden använder människor världen över, medvetet eller omedvetet, molntjänster, där stora mängder personlig information placeras och lagras. Personuppgifter är en av de mest värdefulla tillgångar ett företag kan inneha, och således utnyttjar företag runt om i världen sådan personlig information för kommersiella syften. Samtidigt har statliga myndigheters övervakning av personer och insamlingToday, people all around the world, consciously or unconsciously, use services provided by cloud computing where large amounts of personal data is placed and stored. Personal data is one of the most valuable assets a company can hold, and therefore companies utilise such data for commercial purposes. At the same time, the surveillance powers and the collection of personal data have increased among

Feminina offer och osynliga förövare : en genuskritisk granskning av FN:s användande av militära styrkor och militär maskulinitet i fredsbevarande operationer

Uppsatsen centrerar kring två aktuella frågor: anklagelser om sexuella övergrepp i FN:s fredsbevarande operationer, och konstruerandet av könsroller. De specifika frågeställningarna för uppsatsen är inledningsvis vilka könsroller som konstrueras i primärmaterialet, vilket innefattar tre årliga FN-rapporter. Den andra frågeställningen syftar till att utreda huruvida den konstruerade, militära masku

Come together, right now, over what? : an analysis of the processes of democratization and participatory governance of water and sanitation services in Dodowa, Ghana

Delivering essential services to burgeoning peri-urban cities in the Sub-Sahara will only become an increasing challenge, as the population in this region is expected to double by 2050. Finding effective governance arrangements, institutional settings and building participatory arenas that give a greater voice to citizens and foster greater responsiveness from democratic authorities is a delicate

Kan våldtäktsbrottet baseras på ett samtyckesrekvisit? - En studie av våldtäktsbrottets konstruktion med den engelska samtyckesbestämmelsen som utgångspunkt

Sexualbrott är ett ämne upprör och föranleder en ständigt infekterad debatt. Tilltalade personer som frias efter att ha utsatt offer för sexuella övergrepp mot deras vilja har väckt frågan om grunden för våldtäktsbrottet kan utgöras av ett krav på bristande samtycke. Denna uppsats syftar till att undersöka huruvida den svenska våldtäktsbestämmelsen skulle kunna bygga på ett samtyckesrekvisit och dSexual offences bring forth a sensitive and intense debate. Acquittal of offenders guilty of sexually molesting a victim against its will have arisen the question whether the rape crime ought to be constructed with non-consent as a necessary condition. The thesis’ purpose is to investigate whether the Swedish rape crime could be based on non-consent and consequently replace the provision of today,

The influence and impact of Japan to upbringing the human rights norms in Southeast Asia through the world of business

Japan’s influence in Southeast Asia has been enormous throughout history, whether in its military occupation, culture, or economic ties, and there is no doubt that Southeast Asia has developed under its influence. Have Southeast Asian states then developed and improved their human rights situation because of Japan? Or has Japan aggravated the situation being “blue washed”, by performing its busine

Freedom and Boundaries: Exploring the Influence of Flexible Working Practices on Work-Life Balance in Entrepreneurship

This thesis examines how entrepreneurs organise flexible working practices in self-structured environments and how these shape their perceived work-life balance. Unlike research focused on employees in traditional settings, this study explores entrepreneurs operating with high autonomy and little external structure. Drawing on Self-Determination Theory, Boundary Theory, and Spillover Theory, it in

Entrepreneurs in Knowledge Hubs - A Case Study of a Swedish Knowledge Hub

Entrepreneurship plays an important role in enhancing economic growth, innovation, and social development. Although entrepreneurial success is often linked to individual initiative and risk-taking, knowledge management and networking are recognized as critical components for fostering successful entrepreneurial ventures. The contribution of knowledge hubs in facilitating these elements remains une

Mellan stad och land

I en tätort söder om Stockholm ligger Karlskronaviken, beläget i ett naturskönt, sjönära område där sommarvillor, fritidshus, egnahem och mindre jordbruk samsats om marken sedan sekelskiftet. Med närheten till Rönninges centrum och dess service samt kollektivtrafik till Stockholm och Södertälje är det inte konstigt att området sedan en tid tillbaka exploateras. Dagens bostadspriser i innerstädernaMy master thesis takes place in an urban, yet rural area south of Stockholm called Karlskronaviken. Located in a scenic, lakeside area where holiday homes, private homes and small farms have shared the land since the turn of the 20th century. With the close distance to the town center of Rönninge, its services and public transport to Stockholm and Södertälje, it is no wonder that the area has been

Bevisvärdering i brottmål i ljuset av Balkongfallet

I Sverige är personer oskyldiga till dess att motsatsen är bevisad. För att dömas till ansvar för brott krävs dessutom att det är bevisat bortom rimligt tvivel att gärningspersonen agerat mot ett straffbud. Det är domstolen som har bördan att avgöra ifall motsatsen är bevisad eller inte. Domstolen ska utifrån den presenterade utredning och bevisning som föreligger för och emot de specifika åtalspuIn Sweden, individuals are presumed innocent until proven guilty. To be convicted of a crime, it is also required that it is proven beyond reasonable doubt that the perpetrator acted against a penal provision. The court is entrusted with the task of determining whether the contrary has been proven or not. Based on the investigation and evidence presented for and against the specific charges, the c

Are Brazilian catchments gaining or losing water? The effective area of tropical catchments

Similar to most countries, the Brazilian water resources management considers topographically delineated catchment as a territorial unit for policy implementation. Yet, previous studies have shown that catchments are not hydrologically isolated, and topographic limits often neglect the groundwater boundaries. Thus, studies on effective catchment areas are promising for shedding light on inter-catc

MR Flow Imaging A Study of Flow Effects on the Gradient Echo Sequence

Effects of flow are a fundamental part of magnetic resonance imaging (MRI). Since almost every part of the body contains some kind of flow, the effects are seen in generally all MR images. The presence of flow in an image slice may be a vast source of artefacts but the effects of flow can also be used for diagnostic purposes, for example in magnetic resonance angiography (MRA). In MRA, flow effect

Omission of doxorubicin from the treatment of stage II-III, intermediate-risk Wilms' tumour (SIOP WT 2001) : an open-label, non-inferiority, randomised controlled trial

BACKGROUND: Before this study started, the standard postoperative chemotherapy regimen for stage II-III Wilms' tumour pretreated with chemotherapy was to include doxorubicin. However, avoidance of doxorubicin-related cardiotoxicity effects is important to improve long-term outcomes for childhood cancers that have excellent prognosis. We aimed to assess whether doxorubicin can be omitted safely fro

Cloning and identification of an oxytocin/vasopressin-like receptor and its ligand from insects

More than 20 years ago, an oxytocin/vasopressin-like peptide, CLITNCPRGamide, was isolated from the locust, Locusta migratoria [Proux JP, et al. (1987) Identification of an arginine vasopressin-like diuretic hormone from Locusta migratoria. Biochem Biophys Res Commun 149:180-186]. However, no similar peptide could be identified in other insects, nor could its prohormone be cloned, or its physiolog

Recognising children’s involvement in child and family therapy sessions : A microanalysis of audiovisual recordings of actual practice

Children’s right to involvement in practices that address their well-being is frequently highlighted, yet how children exercise involvement in face-to-face encounters has remained fairly unknown. To fulfil our aim of identifying, describing and defining children’s involvement, we conducted an inductive microanalysis of face-to-face dialogue on audiovisual recordings of naturally occurring therapy Children’s right to involvement in practices that address their well-being is frequently highlighted, yet how children exercise involvement in face-to-face encounters has remained fairly unknown. To fulfil our aim of identifying, describing and defining children’s involvement, we conducted an inductive microanalysis of face-to-face dialogue on audiovisual recordings of naturally occurring therapy

Cold intolerance and neuropathic pain after peripheral nerve injury in upper extremity

Cold intolerance and pain can be a substantial problem in patients with peripheral nerve injury. We aimed at investigating the relationships among sensory recovery, cold intolerance, and neuropathic pain in patients affected by upper limb peripheral nerve injury (Sunderland type V) treated with microsurgical repair, followed by early sensory re-education. In a cross-sectional clinical study, 100 p

Numerical Study of the Influence of Turbulence-Chemistry Interaction on URANS Simulations of Diesel Spray Flame Structures under Marine Engine-like Conditions

The present work performs unsteady Reynolds-averaged Navier-Stokes simulations to study the effect of turbulence-chemistry interaction (TCI) on diesel spray flames. Three nozzle diameters (d0) of 100, 180, and 363 μm are considered in the present study. The Eulerian stochastic fields (ESF) method (with the TCI effect) and well-stirred reactor (WSR) model (without the TCI effect) are considered in

Amr who report

2014 ANTIMICROBIAL RESISTANCE Global Report on Surveillance 2014 ANTIMICROBIAL RESISTANCE Global Report on Surveillance IV WHO Library Cataloguing-in-Publication Data Antimicrobial resistance: global report on surveillance. 1.Anti-infective agents - classification. 2.Anti-infective agents - adverse effects. 3.Drug resistance, microbial - drug effects. 4.Risk management. 5.Humans. I.World Health Or

https://www.sepsis.lu.se/sites/sepsis.lu.se/files/amr_who_report.pdf - 2026-05-24