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Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient
This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo
INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w
Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe
Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i
Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that
Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi
How can increased demands for food and fibre be combined with conservation of biodiversity which often is threatened by agricultural intensification and expansion? This project focus on the relative benefits of segregating or integrating conservation and agricutlural production (land sparing versus land sharing). On one hand it has been suggested that agriculture should be intensive on existing ar
https://www.becc.lu.se/trade-offs-and-synergies-between-biodiversity-conservation-and-ecosystem-services - 2026-05-23
SPSC_A_929739.indd Individual Placement and Support in Sweden — A randomized controlled trial ULRIKA BEJERHOLM , CECILIA AREBERG , CAISA HOFGREN , MIKAEL SANDLUND , MILES RINALDI Bejerholm U, Areberg C, Hofgren C, Sandlund M, Rinaldi M. Author A, Author A. Individual Placement and Support in Sweden — A randomized controlled trial. Nord J Psychiatry 2015;69:57 – 66. Background: Currently there is n
https://www.cepi.lu.se/sites/cepi.lu.se/files/bejerholm_et_al_2015_ips.pdf - 2026-05-24
Programme Syllabus 1. IDENTIFICATION • Name of programme: Master’s Programme in Music, Composition Diploma • Scope of programme in higher education credits: 120 • Cycle: Second • Programme code: KAMKD. 2. DETAILS OF APPROVAL Syllabus approved by the Board of the Faculty of Fine and Performing Arts 18 October 2017. This syllabus is valid from the autumn semester 2017. 3. PROGRAMME DESCRIPTION The M
https://www.mhm.lu.se/en/sites/mhm.lu.se.en/files/newkamkd_komp_diploma_eng.pdf - 2026-05-24
Popular Abstract in Swedish Människan lever inte bara själv, utan tillsammans med en mängd bakterier som lever i kroppen. Större delen av dessa lever i tjocktarmen. Dessa organismer är viktiga för vår hälsa. De stimulerar immunförsvaret, sänker pH i tarmen och gör det ogynnsamt för sjukdomsframkallande bakterier att växa till. Bakterierna lever i symbios med oss och med varandra. Förändringar i taThe human gut flora is important for our well-being. The gut bacteria are able to degrade and metabolize complex carbohydrates. Examples of such carbohydrates are β-mannans. β-Mannans consist of a backbone of β-1,4-linked mannose units and are present in e.g. the endosperm of legumes such as guar or carob. The composition of the β-mannan varies with the plant source. Carob and guar β-mannans are s
