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Sweden has a long history of maintaining population-based registries and biobanks. This has resulted in large sample collections with long follow-up and large numbers of prospectively occurring disease endpoints providing an extensive resource for genetic research. However, the largest biobanks contain sample materials that have previously been considered suboptimal for genetic research. We have
A production-system simulation model for manufacturing cost of a permanent-magnet based rotor, analyzing the influence of uncertain parameters by utilizing the Monte Carlo method. The uncertain parameters studied include investment and bill of materials costs as well as cycle time. The resulting influence of these uncertainties are presented for each case individually, as well as all possible comb
Popular Abstract in Swedish Vid total höftledsartroplastik är cementering av den konstgjorda ledpannan (cupen) ett allmänt sett välfungerande koncept, men frekvensen av lossning och åtföljande omoperation är fortfarande för hög. En av de viktigaste faktorerna för långtidsöverlevnad av protesimplantat är den initialt uppnådda fixationen och stabiliteten. Den föreliggande avhandlingen omfattar såvälIn total hip arthroplasty cemented fixation of the acetabular component is a generally successful concept, but the rate of aseptic loosening and consequent revision surgery is still too high. One of the crucial factors for longterm implant survival is the initial fixation and stability. This thesis comprises experimental and clinical studies, including radiostereometry (RSA) with up to 5 years fol
ISO 9920 defines three insulation calculation methods: global, parallel and serial. It considers global method a general one that works in any situation, and parallel and serial could be used in specific cases. EN ISO 15831 is the basic manikin testing standard. It gives only two possibilities: parallel and serial. The specific requirements for equations’ use are not set as in ISO 9920, e.g. unifo
Popular Abstract in Swedish Aktivitet och förmågan att kunna utföra olika dagliga sysslor är central för människan och har stor betydelse för upplevelse av hälsa. I samband med sjukdom eller skada kan förmågan till aktivitet förändras, och komplexiteten i de dagliga sysslorna blir tydlig. Systemisk skleros (sklerodermi) är en ovanlig bindvävsjukdom, som karakteriseras av förändring av immunförsvarSystemic sclerosis (scleroderma) is a connective tissue disease which, in various ways, influences an individual’s ability to participate in everyday occupations. The general objective of this work was to elucidate the consequences of scleroderma with respect to hand function, everyday occupations and wellbeing, in order to provide a knowledge base suitable for occupational therapy interventions.
The short-chain fatty acids (SCFA) formed from colonic fermentation of indigestible carbohydrates have been suggested to exert different physiological effects. In this thesis the fermentability and SCFA produced from various indigestible carbohydrates in the hind-gut were investigated using balance experiments in rats. In the case of propionate, experiments were also performed to evaluate possibl
The automotive industry is using more and more of Advanced High Strength Steel in order to reduce the weight of the car. Since this will generate more springback, it is of vital importance to be able to predict the amount of springback in the parts. Otherwise, many late changes have to be made in order to fit the parts in their position. In order to increase the ability to understand and test the
Popular Abstract in Swedish I vår omgivning finns det många bakterier, virus och parasiter som kan skada och göra människor sjuka. För att skydda oss mot angrepp av dessa sjukdomsalstrande organismer och andra skadliga ämnen har flera nivåer av skyddsmekanismer utvecklats. Huden, slemhinnorna och det låga pH-värdet i magsäcken är några av de yttre barriärer som hindrar många skadliga organismer atThe aim of this thesis was to characterise the biological functions of the superantigen staphylococcal enterotoxin H (SEH). Superantigens are highly immunostimulatory proteins, which crosslink T cells and antigen presenting cells (APCs). SEH is included in a family of staphylococcal enterotoxins (SEs) produced by certain strains of Staphylococcus aureus. The three-dimensional fold of SEH was dete
An anthology of sermons from the third to the sixteenth century, translated from the original languages (Greek, Latin, Coptic, Old English, Old Norse, Early Modern German and Swedish) into modern Swedish. With introduction on sermons and preaching by the editor.
This paper introduces a new method for combining high resolution parameter estimates with ray-launching based wave propagation prediction. The idea behind the proposed measurement-based ray tracing tool is to use measured data as the input for a ray-launching algorithm. With the developed tool, it is possible to identify dominant propagation phenomena and relate them with the objects in the physic
Tillitsfulla relationer mellan vårdpersonal, administratörer och politiker har en avgörande betydelse för vårdens omställning och det förnyelsearbete som bedrivs. Dessa relationer behöver systematiseras, stödjas för att fyllas med utvecklingskraft. Organisationer som medvetet satsar på att bygga dessa relationer för att bedriva verksamhet skapar innovationer i små steg”. Dessa tankar blev vägledan
