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We showed that, under conditions of experimental chronic hepatitis, excessive increases in the levels of a Ca-binding protein, S-100b, and a neuronal cell adhesion molecule, NCAM, occur in all parts of the brain of Wistar rats. This is accompanied by suppression of locomotor and orientational/research activity of the animals and increase in their stress sensitivity. Treatment by a ketoglutarate an
This dissertation deals with conversational practices through which interactants manage issues of intersubjectivity, i.e. mutual understanding for all practical purposes. Intersubjectivity is understood in a procedural sense, and as built into the infrastructure of interaction, where each next action embodies aspects of how the previous action was understood. This understanding can be inspected by
Reproductive success usually declines in the course of the season, which may be a direct effect of breeding time, an effect of quality (individuals with high phenotypic or environmental quality breeding early), or a combination of the two. Being able to distinguish between these possibilities is crucial when trying to understand individual variation in annual routines, for instance when to breed,
A Course in Miracles (ACIM) is a spiritual teaching that was said to be channelled by Helen Shucman during 1965-1972. Shucman received what she described as an inner dictation, which she wrote down in shorthand. Her collegue and friend; William Thetford was then copy-typing the text. It came to comprise of around 1,200 pages of text, and is presented as a program of self-tuition, aimed to change a
Biological applications of ion beams have recently become a new important research field using single ion hit facilities to study individual living cells and their response to the hit of a counted number of ions. One motivation is the search for a better understanding of the fundamental processes taking place in cells and organs as a result of irradiation. Another comes from the increasing interes
Popular Abstract in Swedish Avhandlingen Fire, Poison, and Black Tears – Metaphors of Emotion in Rebétiko är som titeln anger en studie av metaforer för känslouttryck i rebétikomusikens texter. Den populärmusikaliska genren rebétiko är en utbredd musikstil i det moderna Grekland. Dess rötter kan spåras till det grekiska fastlandet, Mindre Asien, och de grekiska öarna, men den musikaliska formen haThis dissertation is a study of metaphors of emotion in rebétiko song texts. Rebétiko is a major popular-music style of modern Greece, consisting mostly of melancholic songs full of sorrow, disappointment, and misfortune, as well as passion and romance, but also of cheerful songs of revelry and a carefree attitude to life. Rebétiko as a music style developed in the Greek-speaking world and its dia
Imaging plays a crucial role in studying and understanding cerebral small vessel disease. Several important findings have emerged from recent applications of advanced brain imaging methods. In patients with acute lacunar syndromes, diffusionweighted MRI studies have shown that the diagnostic precision of using clinical features alone or combined with CT scan findings to diagnose small vessel disea
We study inhomogeneous random graphs in the subcritical case. Among other results, we derive an exact formula for the size of the largest connected component scaled by logn, with n being the size of the graph. This generalizes a result for the "rank-1 case". We also investigate branching processes associated with these graphs. In particular, we discover that the same well-known equation for the su
Popular Abstract in Swedish Genom att använda marina sedimentkärnor från havbotten kan vi dyka ner i forna tiders hav och förstå hur klimat och havsmiljö har utvecklats över tid. Sedimenten och dess innehåll av olika mikrofossil utgör ett fantastiskt miljöarkiv och ju längre ner i sedimenten vi kommer desto äldre är de vanligtvis. I mitt doktorandprojekt har jag studerat marina sediment från kusteThere is a limited understanding of how the benthic environment within upwelling regions responded to past rapid climatic changes. Within this thesis, a multiproxy approach is applied to two marine sediment cores from two coastal upwelling sites in the low latitude subtropical Atlantic. With a focus on benthic foraminiferal faunal analyses, the response of the benthic environment to rapid climatic
The material quality at high-k interfaces are a major concern for FET devices. We study the effect on two types of InAs nanowire (NW) transistors and compare their characteristics. It is found that by introducing an inner layer of Al2O3 at the high-kappa interface, the low frequency noise (LFN) performance regarding gate voltage noise spectral density, S-Vg, is improved by one order of magnitude p
Elevated cystatin C in blood reflects impaired glomerular filtration rate (GFR), but current cystatin C assays, based on polyclonal antibodies and immunoturbidimetric or nephelometric detection, have several limitations. We evaluated a new immunoassay based on monoclonal antibodies in samples from patients with and without chronic kidney disease (CKD). The study enrolled 170 men without known CKD
Popular Abstract in Swedish Neuroblastom är en allvarlig cancerform som nästan enbart drabbar barn. Denna typ av tumörer hittas i vävnader av det sympatiska nervsystemet (vilket är en del av det icke viljestyrda nervsystemet i kroppen). Allra vanligast är det att tumörerna bildas i binjuren, ett organ placerat strax ovanför njuren. Cancer är en komplex sjukdom och varje tumör är speciell på sitt sCells adapt to oxygen shortage, hypoxia, by inducing a transcriptional shift governed mainly by Hypoxia Inducible Factor (HIF)-1 and HIF-2. In various cancer forms, including neuroblastoma, high expression of HIF-2α correlates with disseminated disease and poor outcome. It has become evident that HIF-1 and HIF-2 are differentially regulated over time and by oxygen levels. HIF-2α is expressed in a
Objective: The 4.2-day half-life I-124 favors its use for positron emission tomography (PET) of monoclonal antibodies (mAbs). However, high positron energy and beta(+)-associated cascade gamma rays pose image resolution and background noise problems for I-124. This study evaluated quantitative PET of an I-124 mAb in tumor-bearing mice. Methods: An R4 microPET (TM) (Siemens/CTIMI, Knoxville, TN) wa
Electron beam optics (particle betatron motion) and trajectory (centroid secular motion) in the FERMI@Elettra free electron laser (FEL) are modeled and experimentally controlled by means of the ELEGANT particle tracking code. This powerful tool, well known to the accelerator community, is here for the first time fully integrated into the Tango-server based high level software of an FEL facility, t
A discussion of the concept and form of the state in early modern Europe, with Danish exemples, in a theme issue on conceptual history.
BACKGROUND: To determine if the common Pro12Ala polymorphism (rs1801282) of the peroxisome proliferator-activated receptor (PPARG) gene is associated with the metabolic syndrome (MetS) or with its individual components in middle-aged Swedish individuals. METHODS: MetS was defined according to the National Cholesterol Education Program/Adult Panel III (NCEP/ATP III), the International Diabetes Fede
