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Essential oils are volatile and can have good antimicrobial activity. We compared the effects of oil of basil ( Ocimum basilicum) and essential oil components ( thymol, carvacrol, and salicylaldehyde) to those of a placebo when placed in the ear canal of rats with experimental acute otitis media caused by pneumococci or Haemophilus influenzae. Progress was monitored by otomicroscopic examination a
