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Aberrant IgG2 antibody response to Neisseria Meningitidis polysaccharide A after vaccination in frequently infected compared to healthy IgA-deficient individuals

In search for a possible explanation of the phenotypic heterogeneity in selective immunoglobulin (Ig)A deficiency, we studied the IgG2 antibody response to meningococcal polysaccharide A (PSA) in IgA-deficient (IgAd) individuals after vaccination with meningococcal A + C polysaccharide vaccine. Two groups of IgAd individuals, one frequently infected and one clinically apparently healthy, as well a

Efficient corrector iteration for DAE time integration in multibody dynamics

Efficient time integration is a key issue in computational multibody dynamics. Implicit time integration methods for stiff systems and constrained systems require the solution of a system of nonlinear equations in each time step. The nonlinear equations are solved iteratively by Newton type methods that are tailored to the structure of the equations of motion in multibody dynamics. In the present

Response criteria for rheumatoid arthritis in clinical practice - how useful are they?

Objective: To compare the performance of the American College of Rheumatology (ACR), European League Against Rheumatism (EULAR), and simple disease activity index (SDAI) response criteria for rheumatoid arthritis at the individual level in an observational cohort. Methods: 184 outpatients were followed using a structured protocol. For each patient, the responses according to ACR 20% and 50%, EULAR

Parental participation in the care of hospitalized children

The purpose of this study was to investigate those parts of the care of hospitalized children that their parents perform, the nursing tasks the parents themselves felt they could manage and whether parents' and staff members' opinions coincided. A questionnaire was given to parents of children between one week and five years of age who were hospitalized at a pediatric surgical department during a

Acupuncture mechanisms for clinical long-term effects, a hypothesis

In our clinical research, we have drawn the conclusion that meaningful long-term (> 6 months) pain relieving effects can be seen in a proportion of patients suffering from nociceptive pain. What are the mechanisms behind this? From the existing experimental data, some important conclusions can be drawn: A significant proportion of the animal research only represents short-term hypoalgesia probably

Sensory nerve inactivation by resiniferatoxin improves insulin sensitivity in male obese Zucker rats

Recent studies have suggested that sensory nerves may influence insulin secretion and action. The present study investigated the effects of resiniferatoxin (RTX) inactivation of sensory nerves ( desensitization) on oral glucose tolerance, insulin secretion and whole body insulin sensitivity in the glucose intolerant, hyperinsulinemic, and insulin-resistant obese Zucker rat. After RTX treatment (0.

Från Koranen till Ben Hur - Gunnar Jarrings samling av östturkiska handskrifter

In 1982, the Swedish diplomat and Turkologist Gunnar Jarring (1907–2002) donated his unique collection of Eastern Turkestan manuscripts to the Lund University Library. The Jarring Collection at Lund is the third biggest collection of Eastern Turkic manuscripts in the world and consists of 560 pieces, many of which are miscellanies. It is a broad collection and represents the history and culture of

Magnetotransport properties of short period GaMnAs/InGaAs superlattices

Magnetotransport properties of GaMnAs/InGaAs superlattice structure and GaMnAs/GaAs single layers have been investigated from 4 to 300 K and magnetic fields up to 22.5 T. All these magnetic semiconductors show the so-called "paramagnetic-to-ferromagnetic phase transition''. However, in GaMnAs/InGaAs superlattice beside the Curie Wiess temperature (T-c similar to 40 K), a new phase transition is ob

Coalescence times and the Meselson effect in asexual eukaryotes

In asexual eukaryotes, the two allelic gene copies at a locus are expected to become highly divergent as a result of the independent accumulation of mutations in the absence of segregation. If sexual reproduction was abandoned millions of generations ago, intra-individual allelic divergences can be significantly larger than in species that reproduce sexually. Owing to the disputed existence of tru

District Heating Substations. Performance, Operation and Design.

This thesis work is concerned with the efficient layout and operation of substations, i.e. those district heating (DH) system units which connect the network and internal building heating systems, such as radiator heating systems and domestic hot water distribution networks. The ambition was to make realistic investigations closely related to practical technologies within the field. The themes of

Exploiting Spin Echo Decay in the Detection of Nuclear Quadrupole Resonance Signals

Nuclear quadrupole resonance (NQR) is a radiofrequency technique that can be used to detect the presence of quadrupolar nuclei, such as the N-14 nucleus prevalent in many explosives and narcotics. In a typical application, one observes trains of decaying NQR echoes, in which the decay is governed by the spin echo decay time(s) of the resonant line(s). In most detection algorithms, these echoes are