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NCN concentration and interfering absorption by CH2O, NH and OH in low pressure methane/air flames with and without N2O

Absorption spectra in the wavelength region around 329 nm have been recorded with the cavity ring-down technique in various low pressure (200 hPa) CH4/air flames, two of which with N2O (nitrous oxide) addition. NCN (cyanonitrene) absorption appears to be significant only in N2O-enriched flames, which also reveal spectrally nearby absorption by NH. In a phi = 1.14, N2O oxidizer volume fraction = 57

Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells

Generation of mesencephalic dopamine (mesDA) neurons from human embryonic stem cells (hESCs) requires several stages of signaling from various extrinsic and intrinsic factors. To date, most methods incorporate exogenous treatment of Sonic hedgehog (SHH) to derive mesDA neurons. However, we and others have shown that this approach is inefficient for generating FOXA2+ cells, the precursors of mesDA

Endogenous modulators of hyperexcitability in epilepsy: electrophysiological and optogenetic delineation of neuropeptide Y mechanisms in interneurons

Epilepsy is one of the most common neurological disorders worldwide, affecting 1% of the general population, and is characterized by a predisposition for the generation of epileptic seizures. Despite having several different aetiologies, a common underlying cause of epilepsy seems to be an acquired imbalance between excitatory and inhibitory circuits in the brain, which leads to hyperexcitability

Efficacy and safety of atomoxetine as add-on to psychoeducation in the treatment of attention deficit/hyperactivity disorder A randomized, double-blind, placebo-controlled study in stimulant-naive Swedish children and adolescents

Objective The primary objective of this study was to assess the impact of atomoxetine in combination with psychoeducation, compared with placebo and psychoeducation, on health-related quality of life (HRQL) in Swedish stimulant-naive pediatric patients with attention deficit/hyperactivity disorder (ADHD). HRQL results will be presented elsewhere. Here, psychoeducation as well as efficacy and safet

Human papillomaviruses in skin cancer and cervical cancer

Popular Abstract in Swedish Papillomvirus (PV) är små virus som förmodligen infekterar alla däggdjur samt fåglar. De papillomvirus som infekterar människa kallas humant papillomvirus (HPV) och kan infektera antingen huden eller slemhinnor. Att livmoderhalscancer orsakas av bestående infektion med HPV har varit känt länge. Man har länge också misstänkt att HPV-infektioner i huden kan orsaka icke-meThe causal relationship between persistent genital infections with human papillomavirus (HPV) and development of cervical cancer is well established. In contrast, the significance of infections with cutaneous HPV for development of non-melanoma skin cancer (NMSC) is not well understood. We have evaluated whether seropositivity to cutaneous HPV is a marker for cutaneous HPV infection and used high

Genetic Variant on Chromosome 12p13 Does Not Show Association to Ischemic Stroke in 3 Swedish Case-Control Studies

Background and Purpose-In a genome-wide association study and subsequent case-control studies, the single-nucleotide polymorphism rs12425791 on chromosome 12p13 was reported to be associated with ischemic stroke, but this could not be validated in a recent well-powered study. We therefore investigated whether an association between ischemic stroke and rs12425791 could be detected in 3 different ca

Rhinovirus and dsRNA Induce RIG-I-Like Receptors and Expression of Interferon β and λ1 in Human Bronchial Smooth Muscle Cells.

Rhinovirus (RV) infections cause exacerbations and development of severe asthma highlighting the importance of antiviral interferon (IFN) defence by airway cells. Little is known about bronchial smooth muscle cell (BSMC) production of IFNs and whether BSMCs have dsRNA-sensing receptors besides TLR3. dsRNA is a rhinoviral replication intermediate and necrotic cell effect mimic that mediates innate

TO901317 regulating apolipoprotein M expression mediates via the farnesoid X receptor pathway in Caco-2 cells

Background: Apolipoprotein M (apoM) may have potential antiatherosclerotic properties. It has been reported that apoM expression could be regulated by many intracellar and extracellar factors. In the present study we further investigated regulation of apoM expression in Caco-2 cells stimulated by a liver X receptor (LXR) agonist, TO901317. Materials and methods: Caco-2 cells were cultured in the p

Partisanship, Ministers, and Biotechnology Policy

Research in public policy and political economy has provided many insights in the evolution of public resistance against genetically modified organisms (GMOs) in the last two decades. But how does the partisan composition of a government, its programmatic orientation and the allocation of cabinet offices affect policy making in this specific area? We argue that the regulation of GMOs is determined

Geographic and Habitat Origin Influence Biomass Production and Storage Translocation in the Clonal Plant Aegopodium podagraria.

Through physiological integration, clonal plants can support ramets in unfavourable patches, exploit heterogeneously distributed resources and distribute resources that are taken up over large areas. Physiological integration generally increases in adverse conditions, but it is not well known which factors determine the evolution of physiological integration. The aim of this study was to investiga

Intermittent PTH((1-34)) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures.

Intermittent Parathyroid Hormone (PTH)((1-34)) has an established place in osteoporosis treatment, but also shows promising results in models of bone repair. Previous studies have been dominated by closed fracture models, where union is certain. One of the major clinical needs for anabolic therapies is the treatment of open and high energy fractures at risk of non-union. In the present study we th

Essential multiple functions of farms in rural communities and landscapes

As farms are consolidated into larger operations and small farms close down for economic reasons, rural areas lose ecological, social and economic functions related to farming. Biodiversity and scenic, open-vista landscapes are lost as fields are left unmanaged. Social and economic benefits such as local job opportunities and meeting places disappear. Four Swedish rural communities were examined t

Att fokusera på "varandet" i en värld av görande. Stöd till personalen i ett palliativt förhållningssätt vid vård- och omsorgsboende för äldre

Popular Abstract in English Background Palliative care is an approach characterized by a holistic view of the person, which supports the individual for living with dignity and with the best possible level of wellbeing until the end of life. Earlier studies have shown that older people do not have the same access to palliative care as younger people do. One reason for this could be that it is diffiThe aim of this thesis was to study nurse assistants’ experience of palliative care and to investigate how an intervention with a focus on a palliative care approach in residential care facilities influenced the nurse assistants and their work situation. The thesis is based on two qualitative and two quantitative studies, focusing on nurse assistants working at residential care facilities for olde