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Low antibiotic resistance rates in Staphylococcus aureus, Escherichia coli and Klebsiella spp but not in Enterobacter spp and Pseudomonas aeruginosa : A prospective observational study in 14 Swedish ICUs over a 5-year period

Background: Intensive care units (ICUs) are hot zones for emergence and spread of antibiotic resistance because of frequent invasive procedures, antibiotic usage and transmission of bacteria. We report prospective data on antibiotic use and bacterial resistance from 14 academic and non-academic ICUs, participating in the ICU-STRAMA programme 1999-2003. Methods: The quantity of antibiotics delivere

Detection of Needle Dislodgement Using Extracorporeal Pressure Signals : A Feasibility Study

Venous needle dislodgement (VND) during dialysis is a rarely occurring adverse event, which becomes life-threatening if not handled promptly. Because the standard venous pressure alarm, implemented in most dialysis machines, has low sensitivity, a novel approach using extracted cardiac information to detect needle dislodgement is proposed. Four features are extracted from the arterial and venous p

Short-range remote sensing of water quality by a handheld fluorosensor system

Laser-induced fluorescence is a powerful measurement method for determining the concentration of organic pollutants as well as the amount of algae in water. It can be applied in remote sensing of natural waters and has the advantages of high speed and sensitivity. In this paper, we present a compact handheld fluorosensor system for water quality assessment. The power of the technique is demonstrat

Identification and validation of VEGFR2 kinase as a target of voacangine by a systematic combination of DARTS and MSI

Although natural products are an important source of drugs and drug leads, identification and validation of their target proteins have proven difficult. Here, we report the development of a systematic strategy for target identification and validation employing drug affinity responsive target stability (DARTS) and mass spectrometry imaging (MSI) without modifying or labeling natural compounds. Thro

X-Ray Dark-Field Imaging of Lung Cancer in Mice

Lung cancer accounts for 1.6 million deaths per year worldwide. The majority of patients are diagnosed at advanced stages of the disease and often present with metastasis. Thus, the 5-year survival rate of lung cancer remains around 15%. Early diagnosis of lung cancer allows for better control of the disease with 5-year survival rates up to around 70%. Chest radiography is the most common techniqu

Investigation of Reverse Filament Formation in ITO/HfO2-based RRAM

To overcome the large discrepancy in speed between computational devices and that of contemporary large capacity non-volatile memory (NVM) technologies, resistive random access memory (RRAM) technologies are seen as promising candidates, offering speed/energy improvements in several orders of magnitude while being 3D integration compatible [1]. Indium-Tin-Oxide (ITO) has several unique properties

Assessment of Metal Cutting Tools using Cost Performance Ratio and Tool Life Analyses

Critical raw materials (CRM) are extensively used in tools for metal cutting, such as in cemented carbide tools (cobalt and tungsten), because they provide desired characteristics of high fracture toughness and wear resistance. Both academia and industry are examining CRM-free material alternatives, such as tools based on polycrystalline diamond (PCD) or ceramic materials. These materials are gene

Yttrande över remissen: En ny Riksbankslag (SOU 2019:46)

Lunds universitet har uppmanats att ge synpunkter på rubricerad remiss. Universitetet lämnar här följande kommentarer vilka har utarbetats vid Ekonomihögskolan vid Lunds universitet av docent Fredrik N G Andersson och professor emeritus Lars Jonung. Inflationsmålet infördes för över 25 år sedan. Villkoren för att bedriva penningpolitik har förändrats på ett omvälvande sätt under detta kvartssekel.

Crack-tip field at steady crack growth and vanishing linear strain-hardening.

A solution to the quasistatically propagating mode III crack in an elastic perfectly plastic solid is obtained as the limit solution for vanishingly small linear strain hardening. A point above or below the crack plane will experience, first, a centered fan slip line field followed at the angle ±32.8° ahead of the crack tip by elastic unloading and, finally, from the angle ±179.7° to the crack sur

A Naturalistic Perspective on Knowledge How : Grasping Truths in a Practical Way

For quite some time, cognitive science has offered philosophy an opportunity to address central problems with an arsenal of relevant theories and empirical data. However, even among those naturalistically inclined, it has been hard to find a universally accepted way to do so. In this article, we offer a case study of how cognitive-science input can elucidate an epistemological issue that has causeFor quite some time, cognitive science has offered philosophy an opportunity to address central problems with an arsenal of relevant theories and empirical data. However, even among those naturalistically inclined, it has been hard to find a universally accepted way to do so. In this article, we offer a case study of how cognitive-science input can elucidate an epistemological issue that has cause

Learning Based Model Predictive Control of Combustion Timing in Multi-Cylinder Partially Premixed Combustion Engine

Partially Premixed Combustion (PPC) has shown to be a promising advanced combustion mode for future engines in terms of efficiency and emission levels. The combustion timing should be suitably phased to realize high efficiency. However, a simple constant model based predictive controller is not sufficient for controlling the combustion during transient operation. This article proposed one learning