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We showed earlier that over-expression of protein kinase C (PKC) epsilon induces neurite outgrowth. The effect is mediated by a region (PKC epsilon PSC1V3) encompassing the pseudosubstrate, the two C1 domains and part of the V3 region, and is independent of the catalytic activity of the enzyme. In this region, residues immediately N-terminal of the C1b domain are crucial for neurite outgrowth. How
Aim: Carbon monoxide (CO) in blood as assessed by the COHb% is a marker of the cardiovascular ( CV) risk in smokers. Non-smokers exposed to tobacco smoke similarly inhale and absorb CO. The objective in this population-based cohort study has been to describe inter-individual differences in COHb% in never smokers and to estimate the associated cardiovascular risk. Methods: Of the 8,333 men, aged 34
Study of Dennis Potter's TV-series Lipstick on Your Collar.
We show that the undular stray light, diffusely scattered by the optical system of a synchrotron beamline, can play an important role in the formation of high-resolution resonant photoelectron (RPE) spectra. The influence of the stray light is mediated through the Stokes doubling effect, with the Lorentzian tail of the spectral function being replaced by a more complicated form. This effect is sho
Review over new research within media pedagogy and a discussion concerning the future of the field
Two types of glassy carbon (GC) powder (i.e., Sigradur K and Sigradur G) have been mixed with mineral oil to obtain glassy carbon paste electrodes (GCPE's). The electrochemical behavior of such electrodes at different percentages of glassy carbon has been evaluated with respect to the electrochemistry of ferricyanide as revealed with cyclic voltammetry and the best paste composition was chosen. GC
This article describes the first Swedish experience with fertility preserving surgery according to the technique of Dargent. Minimally invasive methods gain acceptance in the treatment of other tumours and this method seems to treat adequately and preserve function. The literature is reviewed and discussed. In Sweden about 25-40 women under 30 years of age are each year diagnosed with cancer of th
The relationship between time of HIV-1 detection, appearance of symptoms and disease progression was studied in all 24 HIV-1-infected infants from a cohort of 117 children who were born to HIV-1-infected mothers and monitored from birth. HIV isolation from plasma and mononuclear cells, HIV-1 DNA PCR (polymerase chain reaction) and, retrospectively, a quantitative assay for HIV-1 RNA were used for
Popular Abstract in Swedish I denna avhandling behandlas brosk proteiners roll såsom antigen och tillgänglighet av immunsystemet i artrit. Sex artiklar omfattas, där fyra presenterar nya djur modeller för reumatoid artrit (RA), en visar hur en genetisk störning av ett broskprotein kan förvärra artrit och den sista hur posttransnationell modifiering av kollagen typ II (CII) påverkar T-cells toleranIn this thesis the role of cartilage proteins and their potential as antigen and availability to the immune system in arthritis were investigated. Six papers are included; where four present new animal models for Rheumatoid arthritis (RA), one shows how genetic disorders in cartilage may affect arthritis and the last how posttranslational modification of collagen type II (CII) affects tolerance. P
To investigate the Ca2+-dependent plasticity of sarcoplasmic reticulum (SR) function in vascular smooth muscle, transient responses to agents releasing intracellular Ca2+ by either ryanodine (caffeine) or D-myo-inositol 1,4,5-trisphosphate [IP3; produced in response to norepinephrine (NE), 5-hydroxytryptamine (5-HT), arginine vasopressin (AVP)] receptors in rat tail arterial rings were evaluated a
The present article seeks to advance the theoretical knowledge of entrepreneurial learning by reviewing and synthesizing available research into a conceptual framework that explains the process of entrepreneurial learning as an experiential process. The framework identifies three main components in the process of entrepreneurial learning: entrepreneurs' career experience, the transformation proces
We recently established that two midgestation-derived stromal clones--UG26-1B6, urogenital ridge-derived, and EL08-1D2, embryonic liver-derived--support the maintenance of murine adult bone marrow and human cord blood hematopoietic repopulating stem cells (HSCs). In this study, we investigate whether direct HSC-stroma contact is required for this stem cell maintenance. Adult bone marrow ckit+ Ly-6
The notion of "global warming" has become a major public-domain concept as an environmental threat to our future on earth. Independently of the accuracy of existing prediction of combustion emissions on the climate on earth, the concept of reducing combustion emissions has been an important political driving force in imposing more and more severe restrictions on harmful emissions from combustion.
The breeding biology of a southern population of the little-known Savi’s Warbler Locustella luscinioides is described and compared with other parts of its distribution and other species. Males arrived at the Salreu marshlands, Portugal, in the second week of March whereas females arrived 6–10 days later. Early-arriving males bred earlier and had greater mating and breeding success. Female breeding
Heterogeneous clusters created by doping Ar host clusters with Kr or Xe are shown to have radically different structures from the mixed clusters of the same type created by co-expansion of Ar-Kr or Ar-Xe gas mixtures. In contrast to the co-expansion case, the doped mixed clusters can be produced with Kr or Xe on the surface and Ar in the bulk. With the doping technique it is thus possible to contr
The aim of this study is to demonstrate how the cultural functions of a sacred motif have changed over the years by means of intermedial transformation. The object of study is an ekphrastic poem, "Theotokos", by the Swedish poet Ingemar Leckius. A couple of medieval Orthodox icon paintings - The Vladimir Madonna and The Virgin of the Sign - have served as sources of inspiration for the poet. A myt
