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OBJECTIVE: We synthesized the main findings from an international epidemiologic study on the impact of biopersistent organic pollutants (POPs) on human reproductive function. DATA SOURCES AND EXTRACTION: We used a database with interview and biological data from 2,269 women and their spouses, and 18 published core papers. DATA SYNTHESIS: The study did not provide direct evidence of hormone-like ac
Background: Several sexually transmitted infections (STI) have been reported to interact with human papillomavirus (HPV) in the etiology of cervical cancer. A large cohort study is required to obtain a both unbiased and stable estimate of their effects. Methods: Four major biobanks in the Nordic Countries containing samples from about 1,000,000 subjects were linked with nation-wide cancer registri
The visual behaviour of consumers buying (or searching for) products in a supermarket was measured and used to analyse the stages of their decision process. Traditionally metrics used to trace decision-making processes are difficult to use in natural environments that often contain many options and unstructured information. Unlike previous attempts in this direction (i.e. Russo & Leclerc, 1994
Abstract in UndeterminedNTRODUCTION: Evidence suggests that negative self imagery plays an important role in social anxiety disorder (SAD) as a maintaining factor, and that early memories of traumatic experiences are linked to recurrent catastrophic images. Previous research has showed that cognitive restructuring combined with imagery rescripting of these memories may affect recurrent images resu
National guidelines are being produced at an increasing rate, and politicians and managers are expected to promote these guidelines and their implementation in clinical work. However, research seldom deals with how decision-makers can perceive these guidelines or their challenges in a cultural context. Therefore, the aim of this study was twofold: to investigate how well Promoting Action on Resear
To investigate the feasibility of transplanting human neural progenitor cells (hNPCs) to the retina of nonimmunosuppressed pigs, cultured hNPCs were injected into the subretinal space of 5 adult pigs after laser burns were applied to promote donor cell integration. Postoperatively, the retinal vessels appeared normal without signs of exudation, bleeding, or subretinal elevation. Eyes were harveste
OBJECTIVE:: To investigate the effects of physical exercise during work hours (PE) and reduced work hours (RWH) on direct and indirect costs associated with sickness absence (SA). METHODS:: Sickness absence and related costs at six workplaces, matched and randomized to three conditions (PE, RWH, and referents), were retrieved from company records and/or estimated using salary conversion methods or
In the present study, coping was viewed as both an individualistic and a collective phenomenon, and the investigation assessed how use of collective and individualistic coping strategies was related to sex of respondent and organizational level. These strategies were measured by responses to Swedish versions of the Strategic Approach to Coping Scale and the COPE Inventory. Data were collected by m
The generation of the impact sound by the act of the human walk involves two factors, the characters of the footfall and the shape of the induced floor deflection. The footfall noise is created by the impact excitation and the characters of the footfall depend on the foot-ware: the heels and the frequencies of the footfall. The shape of the floor deflection depends rather on the geometrical walkin
OBJECTIVE: To evaluate the hepatic venous Doppler technique in the diagnosis of premature heart beats in prenatals. Furthermore, to estimate the prevalence and persistency of atrial and ventricular extra beats throughout pregnancy and delivery, and explore the coexistence of congenital heart disease. METHODS: Retrospective study of 256 singleton pregnancies on out-patient attendance due to fetal e
This paper is the fourth in a series discussing experiences in applying the Strategic Systemic Thinking (SST) framework. The framework was originally proposed for the purpose of supporting contextual analysis into complex problem spaces as part of information systems analysis. Previous papers have dealt with an application supporting strategic development of work in an academic university departme
Toll-like receptors (TLRs) are germline-encoded pathogen-recognition receptors that detect different microbial structures and activate the immune system. The human TLR family presently comprises ten members (TLR1-TLR10), each with distinct properties. Although the TLRs protect the host from infection, they have become increasingly implicated in the pathogenesis of various inflammatory diseases, in
Background: Previous studies on domestic violence in Indonesia have focused primarily on women's experiences and little research has been undertaken to understand men's views on domestic violence or their involvement in the prevention of domestic violence. This study aimed to explore men's views on masculinity and the use of violence within marriage, in order to gain knowledge on how to involve me
Fibroblast growth factors (FGFs) regulate the growth and progression of breast cancer. FGF signaling is transduced through FGF receptors 1-4, which have oncogenic or anti-oncogenic roles depending on the ligand and the cellular context. Our aim was to clarify the roles of FGFR1-3 in breast cancer cell growth in vitro and in vivo. Pools of S115 mouse breast cancer cells expressing shRNA against FGF
Besides medical needs, psychotropic medication use in adolescence might be conditioned by the cultural context of the family. This knowledge is relevant for both detecting inequities in healthcare, and identifying information bias in epidemiological studies using psychotropic medication as a proxy for impaired psychological health. Therefore, we investigated whether, independent of needs, the soci
Objective To examine whether erosive hand osteoarthritis (OA) is associated with knee subchondral bone attrition (SBA) and systemic bone mineral density (BMD). Methods Associations of MRI-defined knee SBA with radiographic erosive hand OA were evaluated in 1253 Framingham participants using logistic regression with generalised estimating equations. We also examined the association between the numb
Monitoring of permafrost has been ongoing since 1978 in the Abisko area, northernmost Sweden, when measurements of active layer thickness started. In 1980, boreholes were drilled in three mires in the area to record permafrost temperatures. Recordings were made twice per year, and the last data were obtained in 2002. During the International Polar Year (2007-2008), new boreholes were drilled withi
