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Computational Stability and Adaptive Strategies - An Experimental Study of ODE Software

The algorithmic content of adaptive ODE/DAE software is dominated by a considerable amount of control structures, support algorithms and logic. The control logic has been largely heuristic and lacking support by analysis. In this thesis we study adaptive time-stepping based on control theory, combined with other carefully selected control strategies. Thus we argue that ODE/DAE software can be cons

Mechanisms behind the faceting of catanionic vesicles by polycations: Chain crystallization and segregation

Vesicles composed of an anionic and a cationic surfactant, with a net negative charge, associate strongly with a hydrophobically modified polycation (LM200) and with an unmodified polycation with higher charge density (JR400), forming viscoelastic gel-like structures. Calorimetric results show that in these gels, LM200 induces a rise of the chain melting temperature (T-m) of the vesicles, whereas

Two-dimensional gel electrophoresis of proteins and peptides in bovine milk

Proteins and peptides in bovine milk and colostrum were separated by two-dimensional gel electrophoresis (2-DE). The proteins were separated in the first dimension by isoelectric focusing in the pH ranges 4-7 and 6-11, and in the second dimension by sodium dodecyl sulphate polyacrylamide gel electrophoresis on 12.5% T homogeneous gels. The peptides were separated in the pH range 3-10 in the first

Biological monitoring of methylhexahydrophthalic anhydride by determination of methylhexahydrophthalic acid in urine and plasma from exposed workers

OBJECTIVE: To investigate whether methylhexahydrophthalic acid (MHHP acid) in urine and plasma can be used as a biomarker for exposure to methylhexahydrophthalic anhydride (MHHPA). METHODS: MHHPA in air was sampled by Amberlite XAD-2 and analysed by gas chromatography (GC) with flame ionisation detection. MHHP acid in urine and plasma was analysed by GC with mass spectrometric detection. Workers o

Nt-proANP in plasma, a marker of salt sensitivity, is reduced in type 2 diabetes patients.

Objective. We recently showed that plasma concentration of N-terminal atrial natriuretic peptide (Nt-proANP) is strongly directly related to salt sensitivity. The aims of the present study were to test (i) whether plasma concentration of N-terminal brain natriuretic peptide (Nt-proBNP) is related to salt sensitivity and (ii) whether Nt-proANP, as a marker of salt sensitivity, differs between type

Hepatitis C superinfection in hepatitis C virus (HCV)-infected patients transplanted with an HCV-infected kidney

Hepatitis C virus (HCV) genotypes, determined by polymerase chain reaction with type-specific primers, were studied in 5 already HCV-infected patients receiving kidneys from HCV-infected cadaver donors. Three patients were investigated retrospectively using stored pre- and posttransplantation sera and followed 18-28 months after transplantation. Two recipients with HCV genotype 2b infection had re

Changes of a non-specific defence mechanism in blood serum of piglets induced by prenatal and postnatal administration of alpha-ketoglutarate

The aim of this study was to establish the influence of alpha-ketoglutarate (AKG), administered to pregnant sows from the 91(SI) d of pregnancy to farrowing, and then to piglets from birth to the 30(th) d of life, on lysozyme and ceruloplasmin activity, serum total protein content, and the WBC counts in blood of piglets, at the age of the 14(th) and 30(th) d of their postnatal life. The sows were

The internal rotenone-insensitive NADPH dehydrogenase contributes to malate oxidation by potato tuber and pea leaf mitochondria

Inside-out submitochondrial particles from both potato (Solanum tuberosum L. cv. Bintje) tubers and pea (Pisum sativum L. cv. Oregon) leaves possess three distinct dehydrogenase activities: Complex I catalyzes the rotenone-sensitive oxidation of deamino-NADH, NDin(NADPH) catalyzes the rotenone-insensitive and Ca2+-dependent oxidation of NADPH and NDin(NADH) catalyzes the rotenone-insensitive and C

Comparison of a broad spectrum anti-aging nutritional supplement with and without the addition of a DNA repair enhancing cat's claw extract

Dietary supplements, designed to fortify the antioxidant status of human metabolism, are intended to provide nutritional support against the aging process. The strategy is based on the observation that environmental and metabolic sources of oxidatively generated free radicals damage key macromolecules, such as DNA, that in turn alter physiologic processes, and in turn may contribute to aging and a

Mechanics of the external fixation test in the lumbar spine. A roentgen stereophotogrammetric analysis

STUDY DESIGN: By implanting tantalum indicators percutaneously during application of pedicular screws, lumbosacral mobility could be studied with roentgen stereophotogrammetric analysis in seven patients having a diagnostic external fixation test. OBJECTIVES: To determine the mechanical effects on the segmental mobility during an external fixation test of the lumbar spine. SUMMARY OF BACKGROUND DA

Activated protein C resistance in patients with peripheral vascular disease

PURPOSE: The frequency of activated protein C (APC) resistance, caused by factor V R506Q gene mutation and abnormal APC ratio, in patients with peripheral vascular diseases was analyzed. METHODS: All patients electively admitted to the vascular ward unit of our tertiary care academic medical center from January 1995 through October 1996 (n = 679) were prospectively analyzed using an APC-resistance

New world, but not Old World, monkeys carry several genes encoding beta-microseminoprotein

It was shown by Southern hybridization that cotton-top tamarin and common marmoset, New World monkeys, carry three or more genes encoding beta-microseminoprotein, also known as PSP94. In contrast, the genomes of Old World monkeys, as represented by rhesus macaque and sacred baboon, contain a single gene. Clones containing three different genes encoding beta-microseminoprotein were isolated from a