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Introduction of the xylose pathway from Pichia stipitis into Saccharomyces cerevisiae enables xylose utilization in recombinant S. cerevisiae. However, xylitol is a major by-product. An endogenous aldo-keto reductase, encoded by the GRE3 gene, was expressed at different levels in recombinant S. cerevisiae strains to investigate its effect on xylose utilization. In a recombinant S. cerevisiae strai
Popular Abstract in Swedish Patienter med kroniskt obstruktiv lungsjukdom, KOL, har en försämrad lungfunktion och lider av bronkit och andnöd. Dessa symptom beror troligtvis på en ständigt pågående inflammation i lungan som dels leder till ökad slemproduktion och förträngning av luftrören, dels till emfysem dvs. nedbrytning av lungvävnaden vilket försämrar gasutbytet i lungan. Cigarrettrökning är Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the future. The chronic inflammation in the lungs of these patients is thought to drive the pathogenesis fo
I föreliggande rapport redovisas en fördjupad studie av hur en vattenavvisande impregnering fungerar när det finns sprickor i fasaden.
The relation between the isoform distribution of the myosin 17 kDa essential light chain (LC17) and the mechanical properties of smooth muscle was investigated. The relative content of the basic (LC17b) and acidic (LC17a) isoelectric variants of the 17 kDa myosin light chain was determined in different mammalian smooth muscle tissues. The relative content of LC17b varied between muscles: rabbit re
New neurons are only generated in two places of the postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. We have genetically manipulated the postnatal SVZ progenitor cells with the aim to direct them to a neuronal fate in the striatum. Our result showed that ectopic expression of t
This study aimed to investigate the presence of pain, pain duration, localization(s), intensity, type and pharmacological treatment among older adults living in sheltered accommodation or receiving rehabilitation, as well as the agreement between pain assessments performed by staff and the older adults. Twenty-nine randomly selected older adults (65+ years) and the staff who looked after them part
BACKGROUND: Previous studies have shown that short-term treatment with adrenocorticotrophic hormone (ACTH) has a strong and rapid lipid-lowering effect. In this long-term study of nephrotic patients with idiopathic membranous nephropathy, the influence of ACTH on the serum lipoprotein profile and glomerular function as well as the dose-effect relationship was investigated. METHODS: Fourteen patien
Popular Abstract in Swedish Med föreliggande avhandling vill jag belysa att Chrétien de Troyes Graalsaga, till skilnad från vad de åtskilliga kritiker har påstått, inte bygger på traditionella ridderliga värden, men väl avslöjar en problematisk ideologi. Denna ideologi prövas med hjälp av V. Jouves metod, som beskrivs i hans Poétique des valeurs. Graalsagans värden analyseras ur ett dubbelt perspThis dissertation aims at showing that Chrétien de Troyes' Conte du Graal does not, as often affirmed, uphold traditional chivalrous values, but discloses a problematic ideology, mostly as a result of multiple interactions at the textual level. In order to examine ideology, Le Conte du Graal is analysed in the light of the poetics elaborated by Vincent Jouve in his Poétique des valeurs (2001). Fol
A method for determination of the accessible volume fraction in gels as function of the molecular weight of the solutes is presented. The pore-size distribution is determined by measuring the rate of diffusion of a mixture of solutes into a gel using gel filtration for separation. The solutes, of various sizes, are detected by refractive index measurements. Two marker molecules (blue dextran and g
The photoreceptor cells of the nocturnal spider Cupiennius salei were investigated by intracellular electrophysiology. (1) The responses of photoreceptor cells of posterior median (PM) and anterior median (AM) eyes to short (2 ms) light pulses showed long integration times in the dark-adapted and shorter integration times in the light-adapted state. (2) At very low light intensities, the photorece
This study is based mainly on observations and interviews accomplished on two occasions with nursing assistants employed at two group living units for older people suffering from dementia in Sweden. The interviews and observations were carried out one year apart, before and after a project that also included supervision of managers and nursing assistants. I interviewed 12 nursing assistants, 8 of
During a validation process of the Swedish Knee Arthroplasty Register (SKAR), living registered patients were sent a questionnaire to ask if they had been reoperated on. This gave an opportunity to pose a simple four-point question with respect to patient satisfaction which 95% of patients answered. We analyzed the answers of patients operated on between 1981 and 1995 and found that only 8% of the
Vortices can form when finite quantal systems are set rotating. In the limit of small particle numbers, the vortex formation in a harmonically trapped fermion system, with repulsively interacting particles, shows similarities to the corresponding boson system, with vortices entering the rotating cloud for increasing rotation. For a larger number of fermions, N greater than or similar to 15, the fe
John Ternstedt (1844-1938) var en av de relativt få svenska präster som påverkades av Tübingerteologen J. T. Beck. Dessa kortfattade anteckningar innehåller inga teologiska analyser, men ger tydliga intryck av spiritualiteten i dessa kretsar med dragning åt mystik och distans till nyevangelismen. Vi får inblickar i såväl skolelevens som lantprästens tillvaro i en tid då präst och församlingsbor va
