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Objective: To compare the three year safety and efficacy of cyclosporin and parenteral gold in the treatment of early, active, severe rheumatoid arthritis (RA), and to study the reversibility of cyclosporin associated renal dysfunction in patients who discontinued cyclosporin treatment. Methods: The patients continued to receive cyclosporin or parenteral gold in an 18 month open extension to an 18
An association between severe infant bronchiolitis due to respiratory syncytial virus (RSV) and subsequent wheezing is well documented. High levels of urinary eosinophil protein X (U-EPX) have been related to active disease in asthmatic children. The aim of this study was to analyse whether RSV bronchiolitis leads to an increase in U-EPX levels and whether wheezing is more common in children with
The available evidence suggests that both genes and environment play a crucial role in the development of juvenile-onset myopia. When the human visual system is examined from an evolutionary perspective, it becomes apparent that humans, living in the original environmental niche for which our species is genetically adapted (as hunter-gatherers), are either slightly hypermetropic or emmetropic and
Rapporten behandlar styr- och reglertekniska funktioners inverkan på energiförbrukningen i byggnader. Den omfattar presentation av undersökta objekt med beskrivning av de olika installationssystemen, redogörelse för redan gjorda driftserfarenheter samt beskrivning av energibesparande modifieringar av driftsätt.
eta(c)(2980) production in gammagamma interactions has been detected via its decays into K(s)(0)K(-/+)pi(-/+), K+K-K+K- and K(+)K(-)pi(+)pi(-) in the data taken with the DELPHI detector at LEP1 and LEP2 energies. The two-photon radiative width averaged over all observed decay channels is Gammagammagamma=13.9+/-2.0(stat.)+/-1.4(syst.)+/-2.7 (BR) keV. No direct decay channel eta(c)-->pi(+)pi(-)pi(+)
The analysis of general charge sampling technique is presented in this thesis. Charge sampling integrates input current instead of tracking input voltage to realize high speed and low voltage sampling. The analysis focuses on the performance of general charge sampling circuits for signal capture. The theoretical analysis here can be applied not only for the weak signal capture, but also for the no
(CHICSi) Celsius Heavy Ion Collaboration Si detector system is a high granularity, modular detector telescope array for operation around the cluster-jet target/circulating beam intersection of the CELSIUS storage ring at the The. Svedberg Laboratory in Uppsala, Sweden. It is able to provide identity and momentum vector of up to 100 charged particles and fragments from proton-nucleus and nucleus-nu
We present direct measurements of the ultrafast carrier dynamics around buried nano-scale Schottky contacts with high spatial and time resolution, performed with a novel fermosecond near-field scanning optical microscope, It is shown that high optically excited carrier densities screen the built-in field around a Schottky contact and allow for efficient transport of electrons towards the contact,
We have analyzed the M-bcr breakpoint position in 133 Philadelphia-positive chronic myeloid leukemia patients and correlated the findings with clinical, hematologic, and cytogenetic data. We also investigated the splicing pattern of the BCR-ABL mRNA in 30 patients, using reverse transcriptase PCR. No statistically significant differences were found between breakpoint position within M-bcr and clin
alpha-Cells were identified in preparations of dispersed mouse islets by immunofluorescence microscopy. A high fraction of alpha-cells correlated with a small cell size measured as the average cell diameter (10 microm) and whole-cell capacitance (<4 pF). The alpha-cells generated action potentials at a low frequency (1 Hz) in the absence of glucose. These action potentials were reversibly inhibite
Theoretical oscillator strengths for transitions between the even 4s(2) 4p(2) and the three odd {4s4p(3), 4s(2)4p4d, 4s(2)4p5s} configurations of As+ are reported. Both ab initio, multiconfiguration Hartree-Fock and semiempirical configuration interaction techniques are used. The uncertainty of the results are estimated, by considering the reproduced energy structure, the agreement of results from
Popular Abstract in Swedish Parkinsons sjukdom beror på att de dopamin-producerande cellerna i hjärnan dör. Detta leder till minskad rörlighet, svårigheter i att påbörja och avsluta en rörelse, balanssvårigheter och darrningar (tremor) hos de drabbade patienterna. Varför dopamincellerna dör är oklart och i nulägat kan man inte bota Parkinsons sjukdom, men man kan lindra symptomen med mediciner. PaParkinson's disease (PD) is a neurodegenerative disorder where the midbrain dopaminergic neurons are lost. Presently there is no cure for PD, and the most common treatment is to replace the lost dopamine pharmacologically by administration of the dopamine precursor L-DOPA. This works very well during the initial treatment period, but unfortunately a majority of the patients develop abnormal involu
AIM: The purpose of the study was to explore the effects of using a structured nursing intervention programme in hypertension care. BACKGROUND: Counselling on lifestyle changes to address hypertension helps patients reduce risk factors such as smoking, high alcohol consumption, overweight, dyslipidemia, negative stress and physical inactivity. DESIGN: The study was performed as a pre-test-post-tes
An evolutionary game of individuals cooperating to obtain a collective benefit is here modelled as an n-player Prisoner's Dilemma game. With reference to biological situations, such as group foraging, we introduce a threshold condition in the number of cooperators required to obtain the collective benefit. In the simplest version, a three-player game, complex behaviour appears as the replicator dy
Popular Abstract in Swedish Det mystika arvet: om konsten att erhålla och förklara det (och förstå litegrann): Ett turkiskt exempel.Mystics and amateur politicians in the margin of Turkish society. The specific case of marginalisation in the specific context of my choice provides a wealth of details to be accounted for. All details taken together are real life itself and can thus not be accounted for in a book. Enough can be said, however, about marginalisation in general in order for a meaningful discussion to take place. Bu
We present approximations of varying degree of sophistication to the integral equations for the (gluon) structure functions of a hadron ("the partonic flux factor") in a model valid in the leading log approximation with a running coupling constant. The results are all of the BFKL type, i.e., a power in the Bjorken variable x(B)(-lambda) with the parameter lambda determined from the size alpha(0) o
Background: Two heterologous pathways have been used to construct recombinant xylose-fermenting Saccharomyces cerevisiae strains: i) the xylose reductase ( XR) and xylitol dehydrogenase (XDH) pathway and ii) the xylose isomerase (XI) pathway. In the present study, the Pichia stipitis XR-XDH pathway and the Piromyces XI pathway were compared in an isogenic strain background, using a laboratory host
