The perforated patch whole-cell configuration of the patch-clamp technique was applied to superficial cells in intact mouse pancreatic islets. Three types of electrical activity were observed corresponding to alpha-, beta- and delta-cells. The delta-cells were electrically active in the presence of glucose but lacked the oscillatory pattern seen in the beta-cells. By contrast, the alpha-cells were

Fetal antigen 1 (FA1) is a circulating glycoprotein containing six epidermal growth factor (EGF)-like repeats. FA1's larger membrane-bound precursor is defined by the cDNAs referred to as either human delta-like (dlk) or human adrenal specific cDNA, pG2. In rodents FA1 has also been studied under the names of preadipocyte factor 1 (Pref-1), and zona glomerulosa-specific factor (ZOG). FA1 is abunda

Bülow B, Ahrén B (Lund University, Lund, Sweden) on behalf of the Swedish Research Council Study Group of Endocrine Abdominal Tumours. Adrenal incidentaloma - experience of a standardized diagnostic programme in the Swedish prospective study. J Intern Med 2002; 252: 239-246. OBJECTIVE: To report the 5-year experience of a diagnostic programme for adrenal incidentaloma with special emphasis to diag

The hepatic extraction ratio or propionate and the net hepatic flux of methylmalonate (MMA) were investigated in six Suffolk lambs (32.7 +/- 1.7 kg BW) implanted with catheters in a mesenteric artery and in the portal, hepatic, and ruminal veins and a cannula in the rumen. The lambs were fed a pelleted barley-based diet (1.1 kg DM per day) and subjected to three intravenous infusion protocols sepa

Popular Abstract in Swedish För drygt ett decennium sedan beslutade EU:s dåvarande tolv medlemsstater att upprätta ett gemensamt europeiskt medborgarskap för unionens invånare. Alltsedan dess har det europeiska medborgarskapet varit en omdiskuterad och kontroversiell, men för den breda allmänheten tämligen okänd, innovation i den europeiska integrationen. I Medborgarskap efter nationalstaten ? ettThis thesis is an attempt to formulate a constructive proposal for the ongoing establishment of a post-national European citizenship in the European Union. To the extent that the proposal is post-national, the ambition is to re-conceptualise the idea and ideal of citizenship in a new historical setting. To the extent that the proposal is constructive, the ambition is to develop and employ a method

Popular Abstract in Swedish I många utvecklingsländer i tropiska klimat leder den snabba urbaniseringen till många problem, bl a försämrad termisk komfort i utemiljön. Detta har negativa följder för människors hälsa och välbefinnande och påverkar sociala och kommersiella aktiviteter utomhus negativt. Följaktligen är det mycket viktigt att åstadkomma komfortabla mikroklimat i urban miljö. Den huvuIn many developing tropical countries, rapid urban growth leads to several problems, including increased thermal stress. This has negative consequences for people's health and well-being, and affects social and commercial outdoor activities negatively. Consequently, the creation of thermally comfortable microclimates in urban environments is highly important. The main aim of this thesis is to dee

Dark-grown tigrina-d(12) mutants of barley (Hordeum vulgare L.) accumulate abnormally high amounts of the chlorophyll intermediate protochlorophyllide. In light dark cycles this leads to necrotic segments of the seedling leaves and lethality due to photodynamic damage by the excessive protochlorophyllide accumulated in the dark period. Upon inhibition of the early chlorophyll biosynthetic enzyme,

The use of bio-fuels is becoming more important because of the environmental benefits associated with these fuels. Deactivation of SCR catalysts applied in bio-fuel plants is a major problem due to the high potassium content of bio-fuels and therefore, great potential lies in finding regeneration processes that can be used commercially. Exposing the catalyst surface to sulphate groups generated by

Background: Polymorphisms in and around the CTLA-4 gene have previously been associated to TiD and AITD in several populations. One such single nucleotide polymorphism ( SNP), CT60, has been reported to affect the expression level ratio of the soluble ( sCTLA- 4) to full length CTLA- 4 ( flCTLA- 4) isoforms. The aims of our study were to replicate the association previously published by Ueda et al

This thesis is about Turbo codes - codes constructed via parallel concatenation of two recursive convolutional encoders linked by an interleaver. The focus of the work is on the understanding and design of Turbo codes. This includes thorough investigation of central components that influence Turbo code performances, such as the constituent encoders and the interleaver, as well as the procedure of

Emergence of human immunodeficiency virus type 1 (HIV-1) populations that switch or broaden coreceptor usage from CCR5 to CXCR4 is intimately coupled to CD4(+) cell depletion and disease progression toward AIDS. To better understand the molecular mechanisms involved in the coreceptor switch, we determined the nucleotide sequences of 253 V1 to V3 env clones from 27 sequential HIV-1 subtype B isolat