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Synthesis of dicyanopyridines

Synthesis of the title compounds in four steps using inexpensive collidine and lutidine as starting materials is described.

Conference summary

In this summary I briefly discuss some of the many interesting talks presented at this symposium.

Utilisation of antibiotics in young children: opposite relationships to adult educational levels in Danish and Swedish counties.

Background. Antibiotic utilisation varies profoundly among and within countries, and the extent of antibiotic utilisation correlates with the frequency of bacterial resistance, particularly among children. Hence, it is important to assess which factors may influence prescribing. In addition to variations in morbidity, health-care organisation, drug regulatory and supply systems, prescriber's attit

A flow immunoassay for alkylphenol ethoxylate surfactants and their metabolites - questions associated with cross-reactivity, matrix effects, and validation by chromatographic techniques

This paper describes the application and evaluation of a competitive enzyme flow injection immunoassay (EFIIA) for screening of alkylphenol ethoxylate (APEO) surfactants in different water samples based on a generic immunoassay system previously developed ( see E. Burestedt, C Nistor, U. Schagerlof and J. Emneus, Anal. Chem., 2000, 72, 4171 - 4177). The detection limits for octylphenol ethoxylates

Management of pregnancies with suspected intrauterine growth retardation in Sweden. Results of a questionnaire

BACKGROUND: Diagnosis and management of intrauterine growth retardation during pregnancy remain a major challenge in obstetric care. The objective of this survey was to evaluate the routine clinical management of pregnancies with suspected intrauterine growth retardation at obstetric departments in Sweden. METHODS: In 1997, a questionnaire was sent to all 59 obstetric departments in Sweden. Forty-

Hadronic matrix elements for kaons

We review some work done by us calculating matrix elements for Kaons. Emphasis is put on the matrix elements which are relevant to predict non-leptonic Kaon CP violating observables. In particular, we recall our results for the (B) over cap (K) parameter which governs the (K-0) over bar - K-0 mixing and update our results for epsilon(K)' including estimated all-higher-order CHPT corrections and th

Exogenous protein kinases A and C, but not endogenous prostasome-associated protein kinase, phosphorylate semenogelins I and II from human semen

Semenogelins I and II are the quantitatively dominating proteins in human semen. They comprise the major part of the sperm-entrapping gel formed at ejaculation, which subsequently liquefies due to proteolysis of the gel-forming proteins by prostate-specific antigen (PSA). The mechanism behind gel formation and its physiological significance is not known. We have studied phosphorylation and dephosp

On perfusion estimation using ultrasound

Popular Abstract in Swedish Denna avhandling behandlar analys och förbättringar av en metod att mäta blödgenomströmning i vävnad med kontinuerlig ultraljudsdoppler. Tidigare har stora variationer i detekterat perfusionsvärde observerats som en effekt av speckle, eller våginterferens. Här presenteras en teoretisk modell som förklarar specklefenomenet i en sådan mätsituation. Modellen förutsäger deThis thesis has the main focus on ways to improve the blood perfusion estimate, as obtained from a continuous wave Doppler system. Earlier studies have shown large temporal variations in the detected perfusion estimate, due to speckle. Here, a theoretical model to predict frequency dependent characteristics of speckle in continuous wave ultrasound is presented. The model predicts the frequency shi

Ecology or mythology? Are Whittaker's "gradient analysis" curves reliable evidence of continuity in vegetation?

Whittaker was one of the leading ecologists of his generation, introducing several ideas to plant community ecology. One approach involved deriving environmental-correlation curves in attempts to determine how the abundance of individual species changed along environmental gradients. These curves have been used extensively in the ecological literature of the last 50 years. However, there has been

Influence of temperature on process efficiency and microbial community response during the biological removal of chlorophenols in a packed-bed bioreactor

Two reactors, initially operated at 14 and 23 +/- 1 degrees C (RA and RB, respectively), were inoculated with a bacterial consortium enriched and acclimatized to the respective temperatures over 4 months. The biofilms, formed in the reactors, were studied using scanning electron microscopy, cultivation of the biofilm microflora, and physiological analysis of the isolates. Two bacteria able to mine

Characteristics of Vilnius street prostitutes

Women prostituting in Vilnius City, Lithuania, were studied with regard to their socioeconomic background, drug and alcohol abuse, conditions for prostituting and for the carrier rate of sexually transmitted infectious agents. The 73 women studied represented a group of low-socioeconomic prostitutes with a great age span, i.e. 14-52 years. Forty-five per cent had one or more children. Roughly one-

Radiative lifetimes in Ce I and Ce II

New radiative lifetime measurements based on time-resolved laser-induced fluorescence techniques are reported for 18 even-parity levels belonging to the 4f5d(2)6p and 4f(2)5d(2) configurations of Ce I and 6 even-parity levels belonging to the 5d(2)6s, 4f5d6p, and 4f6s6p configurations of Ce II. Free neutral and singly ionized cerium atoms were produced by laser ablation. The Ce I and Ce II levels

Klinisk forskning måste baseras på team av både kliniker och forskare

Framgångsrik klinisk forskning måste baseras på translationell forskning, där både kliniker och forskare ingår. Sådana team måste utgå från universiteten för att tillgodose kraven på kvalitet. Man bör även diskutera nationella fokusområden för den kliniska forskningen, så att den kompetens som finns i landet tillvaratas.