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Large deviations in rare events simulation: examples, counterexamples and alternatives

When simulating small probabilities, say of order 10-6 or less, by importance sampling, an established principle is to choose the importance sampling distribution as close to the conditional distribution given the rare event as possible. Implementing this often leads into large deviations calculations and exponential change of measure. We survey some of the standard examples where this

DYNAMISK PSYKOTERAPI - teori och praktik

Lärobok i dynamisk psykoterapi bestående av III delar. Del I Teoretiska utgångspunkter Del II Fallbeskrivningar; barn och vuxenpsykoterapi Del III Lärandeguide med seminarieförslag utifrån PBL och casemetodik

Synthetic analogs of sialyl Lewis x

The sialyl Lewis x (SLex) tetrasaccharide is the smallest recognizable ligand for selectins. The selectins constitute a vital part of the inflammatory cascade for recruitment of leukocytes to a site of tissue damage or microbial infection. If too many leukocytes are recruited, normal, not injured, cells can be damaged; a process known from chronic inflammatory diseases such as reumatoid arthritis,

Choir Singing and Socio-Musical Attitudes. Continuity and Change in a Swedish-German Long-Term Perspective

The unfolding of choral history and the development of pedagogical ideas largely depend on a combination of social and musical factors. This is what makes choral research both interesting and challenging. Choral representation of societal change does emerge at different historical periods in the European countries – for example in connection with the French Revolution, in Sweden after World War II

Traceability in food supply chains - Beyond food safety

The former close relation between producer and consumer has gradually disappeared in the industrialisation and globalisation of the food industry. As a result a need for traceability has emerged. It is difficult today for consumers to know if the products they purchase live up to their specifications due to poor communication between the food industry and consumers. This gap between can be address