Two-dimensional electrophoresis and modern image analysis systems have made it possible to study protein expression and regulation of proteins in biological systems. Proteins in the molecular mass region of 20-120 kDa are well investigated and described. However, proteins with masses below 20 kDa are the least investigated as they are rarely seen on 2D-PAGE due to fast migrations in the electric f

The electric field gradient components for the tin nucleus of 34 tin compounds of experimentally known structures and Sn-119 Mossbauer spectroscopy parameters were computed at the scalar relativistic density functional theory level of approximation. The theoretical values of the electric field gradient components were used to determine a quantity, V, which is proportional to the nuclear quadrupole

Aims: To determine quantitative exposure-response relations between work with highly elevated arms and supraspinatus tendinitis, shoulder pain with disability, and shoulder pain without disability. Methods: A cross sectional study was conducted in a historical cohort of 1886 males from three occupational groups. Exposure measurements were performed for four consecutive working days in a random sam

On the basis of the Agent-action-Objective (AaO) paradigm, it will be shown how the transformation of a word model to a geometric space description can be made the founda¬tion for an approach to informational invariants. In particular, the word model of a Causal Loop Diagram (CLD) has been used for simplifying the involved procedures. Since the explanation of a causal loop requires a verbal descri

A hidden Markov regime is a Markov process that governs the time or space dependent distributions of an observed stochastic process. Recursive algorithms can be used to estimate parameters in mixed distributions governed by a Markov regime. Here we derive a recursive algorithm for estimation of parameters in a Markov-modulated Poisson process also called a Cox point process. By this we mean a doub

BACKGROUND: Patients' health beliefs influence their willingness to comply with medical advice. In an earlier study, it was found that men with a previous history of information on risk factors for ischaemic heart disease expressed more feelings of threat to their health than did men without this experience. As anxiety may have adverse effects, such as making patients avoid the desired action, thi

The effects of reduced intercellular coupling in the sinus node were investigated by means of simulations. Coupling was reduced both uniformly, and by introducing localized interaction blocks. In either case, model sinus node element networks typically splitted into frequency domains. These were defined as groups of neighbour elements which all attained the same mean firing frequency. In systems,

Popular Abstract in Swedish Det är lätt att förundras över hur snabbt och lätt barn lär sig behärska språket, med tanke på vilket komplicerat system det är. Barnet ska lära sig betydelser, ordböjningar och principer för hur ord kombineras, det ska behärska ljudsystem, artikulation, betoningsmönster och satsmelodi. Detta ska barnet behärska både för att själv producera språk och för att förstå vad The main purpose of this work was to explore grammar in Swedish children with Specific Language Impairment (SLI), that is children with impaired language development in the presence of normal hearing and otherwise normal development. In four differents studies, spontaneous data from six children with SLI were analysed and compared with data from either younger children with phonological impairmen

The pathophysiology of overactive bladder (OAB) syndrome is complex, and involves both peripheral and CNS factors. Several CNS disorders are associated with OAB, e.g. stroke, spinal cord injury, Parkinson’s disease and multiple sclerosis, and in each disorder the pathophysiology of OAB can be multifactorial. Irrespective of cause or pathophysiology of OAB, antimuscarinic drugs are the first line o

Animal ornamentation was a dominating expression of art in Scandinavia during the period c. 250-1250 AD. In this chapter i am trying to nuance and deepen our understanding of animal ornamentation as a possible cognitive expression. By relating its images to the metaphorical language of early medieval skaldic poetry I suggest that its meanings have been tightly knit to an ideology of honour and war

Popular Abstract in Swedish I denna avhandling beskrivs sambanden mellan funktion i centrala delar av näthinnan, och dess struktur, vid några valda ärftliga och förvärvade sjukdomstillstånd i näthinnan. Denna jämförelse är möjlig genom den relativt nya utvecklingen av multifokalt ERG (mfERG), med vars hjälp centrala näthinnans funktion kan bedömas, samt optisk koherens tomografi (OCT), med vilken In this thesis, retinal function in general, as well as central retinal function and structure are described in selected forms of acquired and hereditary retinal disorders, in order to improve our understanding of underlying pathogenic mechanisms. This comparison has been made possible during the last years, through the relatively recent development of multifocal ERG (mfERG) and optical coherence