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Family conflict and the evolution of sociality in reptiles

Mating systems and parental care are predicted to coevolve because the former dictates the cost-benefit ratio of the latter by affecting genetic relatedness between adults and offspring. Reptiles show only rudimentary forms of sociality and parental care and, hence, could provide important insights into the early stages of the evolution and maintenance of social systems. The skink genus Egernia ex

High modal number and triple trisomies are highly correlated favorable factors in childhood B-cell precursor high hyperdiploid acute lymphoblastic leukemia treated according to the NOPHO ALL 1992/2000 protocols

Between 1992 and 2008, 713 high hyperdiploid acute lymphoblastic leukemias in children aged 1-15 years were diagnosed and treated according to the Nordic Society for Pediatric Hematology and Oncology acute lymphoblastic leukemia 1992/2000 protocols. Twenty (2.8%) harbored t(1;19), t(9; 22), der(11q23), or t(12; 21). The median age of patients with "classic" high hyperdiploidy was lower than that o

The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist

Neutrophils interacting with a chemoattractant gradually become nonresponsive to further stimulation by the same agonist, a process known as desensitization. Receptor desensitization is a highly regulated process that involves different mechanisms depending on which receptor-ligand pair that is studied. Galectin-3, a member of a large family of beta-galactoside-binding lectins, has been suggested

Impaired β-Amyloid Secretion in Alzheimer's Disease Pathogenesis.

A central question in Alzheimer's disease (AD) research is what role β-amyloid peptide (Aβ) plays in synaptic dysfunction. Synaptic activity increases Aβ secretion, potentially inhibiting synapses, but also decreases intraneuronal Aβ, protecting synapses. We now show that levels of secreted Aβ fall with time in culture in neurons of AD-transgenic mice, but not wild-type mice. Moreover, the ability

Do strategy and management matter in municipal organisations?

In Sweden, a large share of public services are organised, produced and delivered by municipalities, large and small, rich and poor. Contextual conditions (size and location) and economic conditions (efficiency and wealth) differ considerably among these service-providing organisations. The question raised in this paper is whether a municipality's economic situation is a direct consequence of the

Does regular exercise during pregnancy influence lumbopelvic pain? A randomized controlled trial

Objective. To study lumbopelvic pain in women randomized to a regular exercise program during pregnancy in comparison to women receiving standard antenatal care. Design. A two-armed, two-center, randomized controlled trial. Setting. St Olavs Hospital, Trondheim University Hospital and Stavanger University Hospital. Population. A total of 855 pregnant women were randomized to intervention or contro

Introducing the Occupational Balance Questionnaire (OBQ)

Objective: The concept of occupational balance is frequently used in occupational therapy but the fact that it has been defined and measured differently is a limitation. This article introduces the Occupational Balance Questionnaire (OBQ), which focuses on satisfaction with the amount and variation of occupations. It consists of 13 items measured on six-step ordinal scales. It has shown good conte

Tiger en svensk? Tystnader om tysk nationalsocialism i svensk press och i Svenska kyrkan 1933–1939

This inaugural lecture in the Royal Swedish Academy of Letters, History and Antiquities discusses the silence in Swedish press and in the Church of Sweden on National socialism, 1933-1939. This silence was neither common nor general, it was often concentrated to certain levels or matters. Silence could be compact, while the silent persons could speak on other levels, in other words, often in a the

Resonant inelastic x-ray scattering and UV-VUV luminescence at the Be 1s edge in BeO

We carried out a combined study of UV-VUV luminescence and resonant x-ray emission from BeO single crystals with incident photon energies in the vicinity of the Be 1s absorption edge. The x-ray emission spectra show that at the Be 1s photoabsorption edge the lattice relaxation processes in the excitation site take place already on the timescale of the radiative decay of the core excitation. Compar

Regulating Audit in Europe: The Case of the Implementation of the EU Eighth Directive in Denmark 1984-2006

This paper analyses the consequences, in Denmark between 1984 and 2006, of the implementation of the European EU Eighth Directive on the qualification of statutory auditors. Although the Eighth Directive envisaged one group of statutory auditors in each Member State, there were two groups of auditors in Denmark, and the implementation of the Directive triggered a long conflict between the two grou

How do the foreign-born perform in inventive activity? Evidence from Sweden

Using a new database that matches patent applications by Swedish residents with demographic information from 1985 to 2007, we examine differences in inventive performance by individuals of foreign and domestic origins, in terms of quantity (probability of patenting, total number of patents per inventor) and quality (forward citations, probability of grant) of patents. We further compare adult and

New insights into the development of retinopathy of prematurity - importance of early weight gain

Evidence is accumulating that one of the strongest predictors of retinopathy of prematurity (ROP), in addition to low gestational age, is poor weight gain during the first weeks of life. In infants born preterm, the retina is not fully vascularised. The more premature the child, the larger is the avascular area. In response to hypoxia, vascular endothelial growth factor (VEGF) is secreted. For app

New constraints on the chemical evolution of the solar neighbourhood and Galactic disc(s) Improved astrophysical parameters for the Geneva-Copenhagen Survey

We present a re-analysis of the Geneva-Copenhagen survey, which benefits from the infrared flux method to improve the accuracy of the derived stellar effective temperatures and uses the latter to build a consistent and improved metallicity scale. Metallicities are calibrated on high-resolution spectroscopy and checked against four open clusters and a moving group, showing excellent consistency. Th

Post harvest improvement of zeaxanthin content of vegetables

Zeaxanthin is a carotenoid produced by plants and has been associated with protection of the photosynthetic machinery under light stress and, together with lutein, in protection of the central retina of the eye. Zeaxanthin levels in blood plasma have been negatively correlated to the development of AMD (age-related macular degeneration) (Gale et al, 2003). Under normal conditions, plants have a lo

Increased plasma apoM levels in the patients suffered from hepatocellular carcinoma and other chronic liver diseases

Objective: To determine plasma apolipoprotein M ( apoM) levels and other lipid profiles in hepatocellular carcinoma ( HCC) patients compared to other chronic liver diseases and normal subjects. Materials and methods: 36 HCC, 68 chronic hepatitis, 29 liver cirrhosis patients and 64 normal controls were subjected in the present study. Serum lipids, lipoproteins, apolipoprotein AI ( apoAI) and apoB w

Applying Mechanistic Models in Bioprocess Development

The available knowledge on the mechanisms of a bioprocess system is central to process analytical technology. In this respect, mechanistic modeling has gained renewed attention, since a mechanistic model can provide an excellent summary of available process knowledge. Such a model therefore incorporates process-relevant input (critical process variables)-output (product concentration and product q

Computationally Efficient Sparsity-Inducing Coherence Spectrum Estimation of Complete and Non-Complete Data Sets

The magnitude squared coherence (MSC) spectrum is an often used frequency-dependent measure for the linear dependency between two stationary processes, and the recent literature contain several contributions on how to form high-resolution data-dependent and adaptive MSC estimators, and on the efficient implementation of such estimators. In this work, we further this development with the presentati

Search for the X-b and other hidden-beauty states in the pi(+)pi(-)gamma(1S) channel at ATLAS

This Letter presents a search for a hidden-beauty counterpart of the X(3872) in the mass ranges of 10.05-10.31 GeV and 10.40-11.00 GeV, in the channel X-b -> pi(+)pi(-)gamma(1S)(-> mu(+)mu(-)), using 16.2 fb(-1) of root s = 8 TeV pp collision data collected by the ATLAS detector at the LHC. No evidence for new narrow states is found, and upper limits are set on the product of the Xb cross section