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Since 1986, 68% of the Listeria monocytogenes isolates from human cases of invasive listeriosis in Sweden are available for retrospective Studies. The aim of the present Study was to characterize 601 human invasive isolates of L. monocytogenes in Sweden from 1986 to 2007 by using serotyping and pulsed-field gel electrophoresis. Since 1996, serovar 4b was permanently reduced to the second or third

Background: This is the first longitudinal study with a 22-year follow-up, based on a national and complete sample, to determine whether the prevalence of hip fracture and the age when it occurs are influenced by migration and by being foreign-born. Cultural background and environmental factors such as UV-radiation and lifestyle during childhood and adolescence may influence the risk of a hip frac

Pickering emulsions are emulsions that are stabilized by fine particles. They have been the focus of considerable research in the past decade due to their properties such as high stability with respect to coalescence and Ostwald ripening, as well as due to advances in nanotechnology that allows us to create and characterize nano-scale structures in new ways. This work reviews some of the recent wo

Background: High activity of cysteine proteases such as legumain and the cathepsins have been shown to facilitate growth and invasion of a variety of tumor types. In breast cancer, several recent studies have indicated that loss of the cysteine protease inhibitor cystatin E/M leads to increased growth and metastasis. Although cystatin E/M is normally expressed in the skin, its role in cysteine pro

Materials that are stored or used in damp climates may be subject to mould growth. However, all materials are not equally susceptible to mould growth. For each specific material, there is a critical moisture level. If this is exceeded, there is a risk that mould fungi will develop on the material. In a building, different constructions are exposed to different climatic conditions. To minimise the

We present a 2nd-order 4-bit continuous-time (CT) delta-sigma modulator (DSM) employing a 2nd-order loop filter with a single operational amplifier. This choice strongly reduces the power consumption, since operational amplifiers are the most power hungry blocks in the DSM. The DSM has been implemented in a 65 nm CMOS process, where it occupies an area of . It achieves an SNDR of 64 dB over a 500

Pavements are constructed using several layers of materials, and their durability depends mainly on the stiffness modulus and thickness of these strata. Surface wave testing is an effective tool to measure the stiffness and thickness of pavement layers. However, measurements are still based on spot testing with fixed receivers and source. The typical large size of pavements and the cost of closing

Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart failure and death(1). We conducted a genome-wide association study (GWAS) in individuals of European ancestry, including 6,707 with and 52,426 without atrial fibrillation. Six new atrial fibrillation susceptibility loci were identified and replicated in an additional sample of individuals of European anc

Exposure to ultrafine particles (UFP) may have adverse health effects. Central monitoring stations do not represent the personal exposure to UFP accurately. Few studies have previously focused on personal exposure to UFP. Sixty non-smoking residents living in Copenhagen, Denmark were asked to carry a backpack equipped with a portable monitor, continuously recording particle number concentrations (

Popular Abstract in Swedish Fetma har blivit ett växande folkhälsoproblem under de senaste decennierna och den epidemiartade utvecklingen har fått stor uppmärksamhet. Faktum är att världshälsoorganisationen WHO uppger att 1.4 miljarder människor är överviktiga och att 65 % av jordens befolkning lever i länder där fler dör av övervikt och fetma än av undervikt. Fetma är nära kopplat till hjärt- ochIn obesity and several other disease scenarios, the measurement of fat accumulation in various organs and tissues has become a sought-after technique in clinical diagnostics and research. Especially, quantitative and non-invasive techniques which also provide images of accumulated fat throughout the body would be valuable. In the typical hospital, magnetic resonance imaging (MRI) is the only techn

Living organisms need to regulate their gene expression in response to environmental signals and internal cues. This is a computational task where genes act as logic gates that connect to form transcriptional networks, which are shaped at all scales by evolution. Large-scale mutations such as gene duplications and deletions add and remove network components, whereas smaller mutations alter the con

Diabetic retinopathy (DR) is the most feared complication of diabetes with an overall prevalence of 21.9-36.8% and may, if untreated, lead to severe visual disability or blindness. DR is histologically characterized by pericyte and endothelial cell loss, formation of acellular vessel strands, micro-occlusions, progressive ischemia, and finally the appearance of neovascularization and fibrosis. Hyp

Background: The orally active quinoline-3-carboxamide tasquinimod [ABR-215050; CAS number 254964-60-8), which currently is in a phase II-clinical trial in patients against metastatic prostate cancer, exhibits anti-tumor activity via inhibition of tumor angiogenesis in human and rodent tumors. To further explore the mode of action of tasquinimod, in vitro and in vivo experiments with gene microarra

We estimated costs associated with injuries to hands from log splitters and circular saws used to cut up firewood and assessed the value of prevention. The study was carried out as a cost of illness study with an incidence approach based on 57 consecutive patients (median age 51; range 8--81) with injuries to the hand or forearm. Twenty-six of the 57 had an amputation which required microsurgery a

Popular Abstract in Swedish Tuberkulos (tbc) är en av de sjukdomar som sedan tusentals år orsakat mest lidande för mänskligheten. Mycobacterium tuberculosis är den bakterie som orsakar tbc hos människor. Att vi lever tätare inpå varandra på grund av växande befolkning globalt gör att denna luftburna smitta kan fortleva. Fattigdom och undernäring är viktiga bidragande orsaker som förklarar varför dRapid, accurate diagnosis and management of TB in HIV-positive individuals is critical for the success of antiretroviral treatment programmes in primary health care in Sub-Saharan Africa. These studies aim to develop and evaluate methods for TB case finding in adults receiving care at Ethiopian health centres. The prevalence of active TB in a prospective cohort of 812 HIV-positive adults was deter