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Humans Use both Form and Motion Information for Heading Perception
It has long been known that humans use the focus of expansion (FOE) in a radial optic flow pattern to perceive their instantaneous direction of self-motion (heading). Here we report that motion-streak-like form information is also used for heading perception. We presented observers with an integrated form and motion display in which the dot pairs of a radial Glass patterns were oriented toward one
Finance, Comparative Advantage, and Resource Allocation
Can financial institutions and markets enhance the discipline imposed by competitive product markets and thus improve resource allocation in the real economy? We address this question in the context of international trade, using disaggregated product-level data from 71 countries exporting to the USA. We show that exported products exit the US market sooner if they stand far away from the exporting
The Effect of Paid Vacation on Health: Evidence from Sweden
This study estimates the causal effect of receiving additional paid vacation days on health. Using register data on the universe of central government employees in Sweden, I exploit an age-based rule stipulated in the collective agreement covering these employees. Identification is achieved by combining a regression discontinuity with a difference-in-differences design to control for time-invarian
Olfactory language and abstraction across cultures
Olfaction presents a particularly interesting arena to explore abstraction in language. Like other abstract domains, such as time, odours can be difficult to conceptualize. An odour cannot be seen or held, it can be difficult to locate in space, and for most people odours are difficult to verbalize. On the other hand, odours give rise to primary sensory experiences. Every time we inhale we are usi
Trump’s Short-Sighted Iran Strategy
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En åldrande värld
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Since its first appearance in the novel La Place de l’étoile (1968), the motif of the police van (panier à salade) has never stopped showing up in Modiano’s works. This article focusses on the scene with the police van in seven novels, in order to show its obsessional character. The analysis shows that the police van appears in a scenario which the reader recognizes from one novel to another, desp
Reform på reform - utan förbättringar
Det digitala arbetslivet : Digitalisering av sjuksköterskeyrket
Att arbeta som sjuksköterska innebär traditionellt ett yrke där man möter och vårdar människor. Oftast patienter, men mötena under en arbetsdag kan också vara anhöriga eller andra vårdprofessioner. Under senare år har yrket förändrats och idag finns allt fler digitala teknologier inblandade i det dagliga arbetet. En del av det arbete som tidigare utfördes i vårdmöten med patienten och ibland denne
Osteoprotegerin autoantibodies do not predict low bone mineral density in middle-aged women
Purpose Autoantibodies against osteoprotegerin (OPG) have been associated with osteoporosis. The aim was to develop an immunoassay for OPG autoantibodies and test their diagnostic usefulness of identifying women general population with low bone mineral density. Methods Included were 698 women at mean age 55.1 years (range 50.4–60.6) randomly selected from the general population. Measurement of wri
Impact of body constitution on complications following pancreaticoduodenectomy : A retrospective cohort study
Background Overweight, defined by body mass index (BMI), is correlated to complications following pancreaticoduodenectomy (PD). The aim of this study was to evaluate the impact of body constitution, measured with different anthropometric measures, and diabetes on complications following PD. Materials and methods Patients who underwent PD between 2000 and 2015 at Skåne University Hospital were retr
Spectrum of HPV types before and after treatment of cervical intraepithelial neoplasia grade 2 and 3
Background To monitor residual disease after treatment of high grade cervical intraepithelial neoplasia (CIN), cytology together with human papillomavirus (HPV) testing are commonly performed. Objectives To analyse the spectrum of HPV types before and after treatment. Study design This register-based study included 446 women treated for CIN2 or 3, where cytology samples had been HPV-tested before
Epilepsy in tuberous sclerosis patients in Sweden – Healthcare utilization, treatment, morbidity, and mortality using national register data
Purpose This study is designed to estimate the prevalence of epilepsy associated with TSC in Sweden and to describe treatment, morbidity, and mortality of TSC patients with epilepsy. Methods Register data for 2004–2014 was obtained from the National Board of Health and Welfare in Sweden. Patients with TSC were identified using ICD-10 codes. Epilepsy was identified using ICD-10 codes, interventions
Heparin-binding protein (HBP) improves prediction of sepsis-related acute kidney injury
Background: Sepsis-related acute kidney injury (AKI) accounts for major morbidity and mortality among the critically ill. Heparin-binding protein (HBP) is a promising biomarker in predicting development and prognosis of severe sepsis and septic shock that has recently been proposed to be involved in the pathophysiology of AKI. The objective of this study was to investigate the added predictive val
Papillary renal cell carcinoma-derived chemerin, IL-8, and CXCL16 promote monocyte recruitment and differentiation into foam-cell macrophages
Papillary renal cell carcinoma (pRCC) is the second most common type of renal cell carcinoma. The only curative treatment available for pRCC is radical surgery. If the disease becomes widespread, neither chemo- nor radiotherapy will have therapeutic effect, hence further research on pRCC is of utmost importance. Histologically, pRCC is characterized by a papillary growth pattern with focal aggrega
Is the incidence of recurrent pregnancy loss increasing? A retrospective register-based study in Sweden
Introduction: The aim of this study was to estimate the incidence of recurrent pregnancy loss (RPL). The prevalence of RPL defined as three or more consecutive miscarriages before gestation week 22, is often stated to be 1%. To our knowledge no study has estimated the incidence of RPL, which might be more informative and clinically relevant than the prevalence. Material and methods: This retrospec
Development and In Vitro Characterization of a Gemcitabine-loaded MUC4-targeted Immunoliposome Against Pancreatic Ductal Adenocarcinoma
CONCLUSION: Successful development and characterization of a MUC4-targeted immunoliposome shows promising results for a targeted treatment and improved retention of gemcitabine for treatment of PDAC.RESULTS: Development of a MUC4-targeted immunoliposome was confirmed and characterized by immunoblots and size characterization. The MUC4-targeted immunoliposome showed a significantly higher targeting
Cancer risks and survival in patients with multiple primary melanomas : Association with family history of melanoma and germline CDKN2A mutation status
Background Worse outcomes have been noted in patients with multiple primary melanomas (MPMs) than in patients with single primary melanomas. Objective We investigated how family history of melanoma and germline CDKN2A mutation status of MPM patients affects risks of developing subsequent melanomas and other cancers and survival outcomes. Methods Comprehensive data on cancer diagnoses and deaths of