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Popular Abstract in Swedish Vi utsätts varje dag för en stor mängd bakterier som skulle kunna göra oss sjuka, men för det mesta håller vi oss ändå friska. Epitelcellerna på hudens yta och på lungornas slemhinna bildar det första försvaret mot sjukdomsframkallande bakterier, dels genom att de utgör en fysisk barriär men också genom att de kan producera små bakteriedödande substanser, så kallade antEvery day we encounter many potentially harmful microbes in our environment. The epithelial linings constitute an anatomical barrier protecting us and they also produce antimicrobial polypeptides (AMPs) that act as a chemical barrier. These AMPs are small and positively charged, killing a broad range of microbes rapidly. They can either be constitutively produced or rapidly induced when epithelial

Viruses are considered the simplest form of live. A virus is basically composed of genomic material surrounded by a protecting capsid. Today, full molecular details of many viruses are known, and several subclasses can be discerned. In this review, we present recent advances made over the past few years obtained from theoretical considerations and model simulations to improve our understanding on

In this paper we demonstrate how surface site specific experimental information can be obtained from free low nanometer scale clusters using photoelectron spectroscopy utilising synchrotron radiation. In addition, we show how it can be used to gain insight into the geometry and surface structure of the clusters. The present experiments were conducted on alkali metal halides, RbCl and CsCl, which w

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Objectives To study clinical predictors for radiographic progression after 1 year in an early rheumatoid arthritis (RA) trial. Methods In the SWEFOT trial population, disease modifying antirheumatic drug (DMARD) naive RA patients started methotrexate; 3-month responders (DAS28 <3.2) continued (n=147), while non-responders were randomised to addition of sulfasalazine +hydroxychloroquine (n=130) or

Objectives: Rhinomanometry before and after decongestion distinguishes a nasal airway organic stenosis from congestion of nasal mucosa in patients with nasal stuffiness. Together with rhinoscopy and patient history, it is used to decide if nasal surgery would benefit the patient. Rhinomanometry measurements should thus be reliable and reproducible. Materials and methods: We performed repetitive ac

Aim. To establish the prevalence of restrictive eating problems, the overlap and association with attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorders (ASD) and to estimate the heritability of eating problems in a general population sample of twins aged 9 and 12. Methods. Parents of all Swedish 9- and 12-year-old twin pairs born between 1993 and 1998 (n = 12,366) were int

A search is presented for the direct pair production of a chargino and a neutralino [Formula: see text], where the chargino decays to the lightest neutralino and the [Formula: see text] boson, [Formula: see text], while the neutralino decays to the lightest neutralino and the 125 GeV Higgs boson, [Formula: see text]. The final states considered for the search have large missing transverse momentum

Currently there is no coherent or sustainable water cooperation among the five states—Israel, Jordan, Lebanon, Palestinian territories and Syria—that share the Jordan River. Why do people not cooperate on sustainable river basin management, even if it seems the most rational course from the perspective of economic benefits? I hypothesize that the political uses of citizenship, identity and securit

While the risk of TB is elevated in HIV-positive subjects with low CD4 cell counts, TB may in itself be associated with CD4 lymphocytopenia. We investigated markers of immune activation (neopterin) and inflammation (CRP) in TB patients with and without HIV coinfection and their association with CD4 cell levels, and determined their predictive capacity as alternative markers of advanced immunosuppr

Aims. The nature of the thick disc and its relation to the thin disc is presently an important subject of debate. In fact, the structural and chemo-dynamical transition between disc populations can be used as a test of the proposed models of Galactic disc formation and evolution. Methods. We used the atmospheric parameters, [alpha/Fe] abundances, and radial velocities, which were determined from t

The title compound, (C21H22P)(2)[Cu2I4], prepared from reaction between copper powder, iodine and isopropyl triphenylphosphonium iodide in hydroxyacetone (acetol), shows an already known Cu2I42- anion with a planar conformation [Cu-I range = 2.5108 (3)-2.5844 (3) angstrom and I-Cu-I range = 110.821 (10)-125.401 (10)degrees].

Program parallelization and distribution becomes increasingly important when new multi-core architectures and cheaper cluster technology provide ways to improve performance. Using declarative languages, such as constraint programming, can make the transition to parallelism easier for the programmer. In this paper, we address parallel and distributed search in constraint programming (CP) by proposi

Perfluoroalkyl substances (PFASs) can interfere with male reproductive function, but evidence in humans is limited. Six hundred four fertile men (199 from Greenland, 197 from Poland and 208 from Ukraine) were enrolled in the study. We measured four PFASs in serum (PFOS, PFOA, PFNA and PFHxS) and concurrent DNA damage in spermatozoa by sperm chromatin structure assay (SCSA) and in situ terminal deo