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Decomposition pathways in nano-lamellar CVD Ti0.2Al0.8N

Recent progress in chemical vapour deposition (CVD) technology has enabled synthesis of metastable cubic Ti1−xAlxN coatings with x as high as 0.8–0.9. These coatings have unique micro- and nano-structures consisting of grains with epitaxially grown nanolamellae with different Al/Ti ratios, and exhibit exceptional hardness and resistance to wear and oxidation. Here, the thermal stability and decomp

Exposure to long-term source-specific transportation noise and incident breast cancer : A pooled study of eight Nordic cohorts

Background: Environmental noise is an important environmental exposure that can affect health. An association between transportation noise and breast cancer incidence has been suggested, although current evidence is limited. We investigated the pooled association between long-term exposure to transportation noise and breast cancer incidence. Methods: Pooled data from eight Nordic cohorts provided

Pivmecillinam with Amoxicillin/Clavulanic acid as step down oral therapy in febrile Urinary Tract Infections caused by ESBL-producing Enterobacterales (PACUTI)

BackgroundOral treatment alternatives for febrile urinary tract infections are limited in the era of increasing antimicrobial resistance. We aim to evaluate if the combination of pivmecillinam and amoxicillin/clavulanic acid is non-inferior to current alternatives for step-down therapy in adult patients with febrile urinary tract infection.MethodsWe plan to perform an investigator-initiated non-in

Association Between Prenatal and Early Postnatal Exposure to Perfluoroalkyl Substances and IQ Score in 7-Year-Old Children From the Odense Child Cohort

Perfluoroalkyl substances (PFAS) are persistent chemicals capable of crossing the placenta and passing into breast milk. Evidence suggests that PFAS exposure may affect brain development. We investigated whether prenatal or early postnatal PFAS exposure was associated with intelligence quotient (IQ) scores in schoolchildren from the Odense Child Cohort (Denmark, 2010–2020). We assessed concentrati

Design of an AI Support for Diagnosis of Dyspneic Adults at Time of Triage in the Emergency Department

We created an AI support for diagnosis in dyspneic adults at time of triage in the emergency department.Complete data from an entire regional health care system was analyzed, to find AI-derived, unknown, important diagnostic predictors. Most important were prior diagnoses of heart failure or COPD, daily smoking, atrial fibrillation/flutter, life difficulties and maternal care.Sensitivity for AHF,

Neuropsychological outcome after cardiac arrest : results from a sub-study of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial

Background: Cognitive impairment is common following out-of-hospital cardiac arrest (OHCA), but the nature of the impairment is poorly understood. Our objective was to describe cognitive impairment in OHCA survivors, with the hypothesis that OHCA survivors would perform significantly worse on neuropsychological tests of cognition than controls with acute myocardial infarction (MI). Another aim was

Measurements of the laminar burning velocities of small alkyl esters using the heat flux method : A comparative study

Consistent datasets of the laminar burning velocity, LBV, for homologous fuels are indispensable for the elucidation of the structure-reactivity trends and the development and validation of pertinent detailed kinetic models. In the present study, all available LBV measurements for small alkyl esters obtained using the heat flux method have been reviewed. New results of the LBV for methyl propionat

Degradation of 75 organic micropollutants in fresh human urine and water by UV advanced oxidation process

In household wastewater, a large proportion of organic micropollutants (OMPs) load is attributed to human urine. OMPs could pose a risk to human and environmental health when urine collected in source-separating sanitation systems is recycled as crop fertiliser. This study evaluated degradation of 75 OMPs in human urine treated by a UV-based advanced oxidation process. Fresh urine and water sample

Activation of 2D cobalt hydroxide with 0D cobalt oxide decoration for microplastics degradation and hydrogen evolution

The 2D semiconductors are important players in environmental and energy fields due to their unique catalytic and physical properties defined by their dimensionality. Versatile functionalities on one 2D matrix will enlarge its application scopes but require dedicated engineering paths. In this work, we present a cross-dimensional strategy by decorating 0D Co3O4 onto 2D Co(OH)2 to form a multifuncti

Effect of Desmosterol, Lathosterol and Coprostanol on the phase behaviour of phospholipid membranes

Sterols have played an important role in membrane evolution. The effect of these molecules, particularly the naturally occurring ones, such as cholesterol, ergosterol, lanosterol, phytosterols and oxysterols on the properties of lipid model membranes have been extensively investigated. Unfortunately, other naturally occurring sterols such as desmosterol and lathosterol have received very little at

Comorbidities in people with hand OA and their associations with pain severity and sensitization : Data from the longitudinal Nor-Hand study

Objective: To determine whether the comorbidity burden and co-existing comorbidities are cross-sectionally and/or longitudinally associated with pain and pain sensitization in a cohort study of people with hand OA. Design: We examined whether comorbidity burden and individual comorbidities based on the self-administered Comorbidity Index (range: 0–42) at baseline were associated with pain outcomes

Comparison of dyskinesia profiles after L-DOPA dose challenges with or without dopamine agonist coadministration

Many patients with Parkinson's disease (PD) experiencing L-DOPA-induced dyskinesia (LID) receive adjunct treatment with dopamine agonists, whose functional impact on LID is unknown. We set out to compare temporal and topographic profiles of abnormal involuntary movements (AIMs) after L-DOPA dose challenges including or not the dopamine agonist ropinirole. Twenty-five patients with PD and a history

Cost-optimal analysis of energy efficient hvac solution-sets for low-energy apartment buildings

Numerous cost-optimal studies have been undertaken by EU member states to define minimum energy performance requirements for buildings within that member state in accordance with the Energy Performance of Buildings Directive. As few of these studies have examined the effect of heating and ventilation system parameters on life cycle cost (LCC) and energy use in detail, this paper analysed 84 HVAC s

Progressive marine oxygenation and climatic cooling at the height of the Great Ordovician Biodiversification Event

The oxygen content of ancient seawater has been hypothesized to be a major controlling factor for biodiversity throughout Earth's history. The Great Ordovician Biodiversification Event (GOBE) represents one of the largest increases in biodiversity during the Phanerozoic, with peak rates of diversity occurring in the Middle–Late Ordovician. Multiple causal factors have resulted in this long-term ad