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Background & aims: Epidemiological evidence on ultra-processed food (UPF) and cause-specific mortality remains limited and mixed. Molecular mechanisms underlying UPF intake and mortality remain unexplored. This study aimed to evaluate the associations between UPF consumption, metabolic signatures, and all-cause, premature, and cause-specific mortality. Methods: This study included 27670 partic
Recent epidemiological studies have suggested a positive association between ultra-processed food consumption and breast cancer risk, although some studies also reported no association. Furthermore, the evidence regarding the associations between intake of food with lower degrees of processing and breast cancer risk is limited. Thus, we investigated the associations between dietary intake by degre
The R¨onneholm-Ager¨od peatland complex, situated in central Scania, contains numerous archaeological sitesdiscovered since the 19th century. Two sediment sequences were obtained at the Ager¨od peatland to compare thesediment stratigraphy with a previous sequence obtained in 1960 to detect any modern-day changes and toestablish the Holocene environmental development in the area. To clarify the tim
Atmospheric new particle formation (NPF) is a naturally occurring phenomenon, during which high concentrations of sub-10 nm particles are created through gas to particle conversion. The NPF is observed in multiple environments around the world. Although it has observable influence onto annual total and ultrafine particle number concentrations (PNC and UFP, respectively), only limited epidemiologic
IntroductionResearch evidence suggests that radiographers often rely on previous training, traditional practices, work experience and protocols developed within the department rather than up-to-date research-based evidence in their daily practice. The aim of the study was to investigate factors that might impact the development of evidence-based practice amongst radiographers in clinical public se
The current literature on resilience shows a trend toward a dynamic process conceptualization, moving away from the previous trait-approach. However, the term “dynamic” is increasingly treated as a buzzword and is thereby oversimplified in the literature. The aim of this article is to develop a unified language pertaining to resilience as a dynamic process, so as to ensure progress in this field.
Interpretability has become a crucial component in the Machine Learning (ML) domain. This is particularly important in the context of medical and health applications, where the underlying reasons behind how an ML model makes a certain decision are as important as the decision itself for the experts. However, interpreting an ML model based on limited local data may potentially lead to inaccurate co
Background. Aortic stiffness is a marker of vascular ageing. Non-conventional risk markers reflecting vascular ageing are largely unexplored. We aimed to investigate the relationship between self-perceived age (SPA) and self-rated health (SRH) with aortic stiffness in the general population. Methods. Cross-sectional assessment of 3760 participants from two Swedish population-based cohorts (mean ag
Railway incidents undermine both punctuality and capacity. As traffic volumes increase, the frequency of these incidents is also expected to increase, driven by higher asset utilization, reduced time for maintenance, and further worsened by climate change. This highlights the importance of efficient incident management and corrective maintenance. This study uses a combination of exploratory data a
BackgroundIn a previous phase II trial, intraperitoneal local anaesthetics shortened the time interval between surgery and adjuvant chemotherapy, an endpoint associated with improved survival in advanced ovarian cancer. Our objective was to test this in a phase III trial.MethodsA double-blind, phase III parallel superiority trial was conducted at two university hospitals in Sweden, within a public
Dynamic polyimine-amide networks with exceptional properties, including high flexibility, excellent thermal stability and dual closed-loop circularity were designed by combining dynamic covalent imine-functionalities with amide-chemistry. The solvent free up-scalable synthesis started from carboxyl-functionalization of lignin-derivable aldehydes followed by melt polycondensation with a triamine to
There is currently intensive research on the development of biobased polymers as potential alternatives to the environmentally hazardous isocyanate-based polyurethanes. In this context, polythioureas (PTUs) form a particularly attractive target because they can be synthesized by using isothiocyanates, a class of molecules that can be found in nature with expected low toxicity. Herein, a serie
In this paper, we discuss the ethical concerns that may arise from the synthesis of human DNA. To date, only small stretches of DNA have been constructed, but the prospect of generating human genomes is becoming feasible. At the same time, the significance of genes for identity, health and reproduction is coming under increased scrutiny. We examine the implications of DNA synthesis and its impact
Digital contact tracing substantially improves the identification of high-risk contacts during pandemics. Despite several attempts to encourage people to use digital contact-tracing applications by developing and rolling out decentralized privacy-preserving protocols (broadcasting pseudo-random IDs over Bluetooth Low Energy-BLE), the adoption of digital contact tracing mobile applications has been
The spread of global multistakeholder partnerships (MSPs) for the2030 Agenda for sustainable development has generatedsignificant expectations on policy synergies and transformativegovernance. This article contributes to the study of the currentgeneration of MSPs by focusing on the self-legitimation attemptsthat MSPs undertake to justify their authority. We compare theself-legitimation claims of a
