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Circadian clocks are biological timekeepers that allow living cells to time their activity in anticipation of predictable environmental changes. Detailed understanding of the circadian network of higher plants, such as Arabidopsis thaliana, is hampered by the high number of partially redundant genes. However, the picoeukaryotic alga Ostreococcus tauri, which was recently shown to possess a small n
Circadian rhythms are ubiquitous in eukaryotes, and coordinate numerous aspects of behaviour, physiology and metabolism, from sleep/wake cycles in mammals to growth and photosynthesis in plants. This daily timekeeping is thought to be driven by transcriptionaltranslational feedback loops, whereby rhythmic expression of clock- gene products regulates the expression of associated genes in approximat
The 24-hour rhythms of the circadian clock [1] allow an organism to anticipate daily environmental cycles, giving it a competitive advantage [2, 3]. Although clock components show little protein sequence homology across phyla, multiple feedback loops and light inputs are universal features of clock networks [4, 5]. Why have circadian systems evolved such a complex structure? All biological clocks
INTRODUCTION: Visually impaired patients may experience visual hallucinations due to the Charles Bonnet syndrome (CBS). While benign in nature, these hallucinations may cause distress in those unfamiliar with the phenomenon. The overall purpose of this study was to determine the degree of awareness of CBS in patients referred to our retina clinic.MATERIAL AND METHODS: Consenting patients attending
This study seeks to advance the understanding of board empowerment in small companies. Predictions based on agency and resource dependency theories were used to examine how contingency factors correlate with board empowerment, in this study conceptualized as a larger number of board members, a higher representation of outside directors, and separate CEO and board chair positions. Statistical analy
A population of cerebrovascular nerve fibers have recently been found to store serotonin (5-hydroxytryptamine; 5-HT). There is reason to assume that these 5-HT-containing fibers have a sympathetic rather than an intracerebral origin. This was further elucidated in the present study in which the uptake mechanisms of 5-HT and noradrenaline (NA) were characterized and compared in rat pial arteries by
Reduction of energy use in buildings is fundamental for sustainable development. A computer program for the prediction of energy use in buildings was assessed by comparisons with the energy performance of existing buildings. The program was then used to evaluate the energy saving characteristics of concrete such as air tightness and heat capacity. The impacts on global environmental aspects and li
Objective: To investigate the potential of acetic acid supplementation as a means of lowering the glycaemic index (GI) of a bread meal, and to evaluate the possible dose - response effect on postprandial glycaemia, insulinaemia and satiety. Subjects and setting: In all, 12 healthy volunteers participated and the tests were performed at Applied Nutrition and Food Chemistry, Lund University, Sweden.
A control diet without supplemental fat and four diets containing 8% of coconut oil, rapeseed oil, fish oil or sunflower oil were fed to lactating sows in order to investigate the lipid absorption capacity of their progeny in terms of pancreatic enzyme activity, hormonal regulation, and bile salt concentration. In addition, the effect of age was studied during the four week suckling period, and du
Hyperplasia of middle-ear mucosa (MEM) during otitis media (OM) is thought to be partially mediated by the actions of growth factors and their receptors. The intracellular pathway leading from the small G-protein Ras to the extracellular regulated kinases (Erks) often links growth factor stimulation to cellular proliferation. This study assessed whether this pathway is involved in MEM hyperplasia
Cytogenetic aberrations have been reported in 45,000 human neoplasms. Structural balanced rearrangements are associated with distinct tumor subtypes with remarkable specificity and have been essential for identifying genes involved in tumorigenesis. All balanced rearrangements that have been characterized molecularly act by deregulating a gene in one of the breakpoints or by creating a fusion gene
Rome in Sweden? The Catholic Offensive in Ecumenical-National Context Since World War II, ecumenical principles have been used as historical measures. This has led to re-interpretations of historical events and to alterations of sources, for example the letters and diaries by Elisabeth Hesselblad, the renewer of St. Birgitta’s order. In the literature on the Swedish Archbishop Nathan Söderblom, th
The hydrophilic/hydrophobic properties of the membrane material have an important influence on the membrane flux reduction when treating solutions containing hydrophobic solutes. Different methods of measuring the hydrophobic properties of membranes have been evaluated; measurement of the contact angle being the most commonly used method. In this investigation the flux reduction of eight membranes
