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Hexameric arginine repressor, ArgR, bound to L-arginine serves both as the master transcriptional repressor/activator at diverse regulons in a wide range of bacteria and as a required cofactor for resolution of ColE1 plasmid multimers. Multifunctional ArgR is thus unusual in possessing features of specific gene regulators, global regulators, and non-specific gene organizers; its closest functional
As digital photography is being increasingly used in clinical medicine, we devised a software program for 'on screen' image analysis, which allows distance, angle, and area to be measured. In this study, 30 photos were evaluated by 10 observers, so 3000 observations were used to test the reproducibility of the measurements. The results showed excellent reproducibility within observer, between obse
In this study an analysis of G.W. Allport's psychology of religion was carried out from the perspective of personal equation with the aim of establishing an interchange between a scholarly and personal sphere in Allport's views of psychology of religion. A content analysis of Allport's collected scholarly writings on psychology of religion, and largely unpublished personal sources previously not u
Popular Abstract in Swedish ”Stat och kommun i makt(o)balans. En studie av flyktingmottagandet.” Denna avhandling handlar om relationen mellan stat och kommun, närmare bestämt i Sverige idag. Dock ses den inte, såsom brukligt, som en hierarkisk relation utan som ett ömsesidigt beroende där staten och kommunerna är beroende av varandra. Detta ömsesidiga beroende kan vara symmetriskt, att båda aktörAlready from the title of this dissertation can two important points be made. The first is that the dissertation is about the relationship between central and local government, more specifically in Sweden today. The second point is that this relationship is seen from a balance of power perspective, where the relative power of the actors is an empirical question rather than derived from a given hie
New basis sets of the atomic natural orbital (ANO) type have been developed for the first, second, and third row transition metal atoms. The ANOs have been obtained from the average density matrix of the ground and lowest excited states of the atom, the positive and negative ions, and the atom in an electric field. Scalar relativistic effects are included through the use of a Douglas-Kroll-Hess Ha
PURPOSE: To determine whether intense laser-produced x rays have an increased radiation hazard. MATERIALS AND METHODS: Mammalian cells were exposed to x rays from a laser-produced plasma that produced ultrahigh peak absorbed dose rates, up to a factor of 10(10) higher than those produced by conventional x rays used in imaging. The cell survival was studied as a function of the absorbed dose. The s
Whether migrating birds compensate for wind drift or not is a fundamental question in bird migration research. The procedures to demonstrate and quantitatively estimate wind drift or compensation are fraught with difficulties and pitfalls. In this paper, we evaluate four methods that have been used in several studies over the past decades. We evaluate the methods by analysing a model migratory mov
Popular Abstract in Swedish Torgny Segerstedt, den kände chefredaktören för Göteborgs Handels- och Sjöfartstidning, hade utkämpat strider före nazismens tid. Som ung kallades han till docent till Lund på en underkänd avhandling. Disputationen hade ägt rum i maj 1903 vid den teologiska fakulteten i Uppsala. Efter underkännandet beslöt alltså den teologiska fakulteten i Lund att kalla Segerstedt tilOn 1st September 1903, the Faculty of Theology at the University of Lund took the decision to appoint Torgny Segerstedt as a senior lecturer in spite of his failed doctoral dissertation. The public defence of his thesis had taken place on 28th May in the same year before the Faculty of Theology at Uppsala. It was thus after his failure that the Faculty at Lund nevertheless decided to invite him to
We consider the origin of the so-called S stars orbiting the supermassive black hole at the very center of the Galaxy. These are usually assumed to be massive main-sequence stars. We argue instead that they are the remnants of low-to-intermediate mass red giants that have been scattered into near-radial orbits and tidally stripped as they approach the central black hole. Such stars retain only low
Here, the ligand binding, activation, and tissue distribution of the orphan G protein-coupled receptor (GPCR) GPR92 were studied. GPR92 binds and is activated by compounds based on the lysophosphatidic acid (LPA) backbone. The binding of LPA to GPR92 was of high affinity (K(D) = 6.4 +/- 0.9 nM) and led to an increase in both phosphoinositide hydrolysis and cAMP production. GPR92 is atypical in tha
The topography of the antigen-binding site as well as the number and the positioning of the antigen contact residues are strongly correlated with the size of the antigen with which the antibody interacts. On the basis of these considerations, we have designed a focused scFv repertoire biased for haptens, designated the cavity library. The hapten-specific scFv, FITC8, was used as a scaffold for lib
The analysis of general charge sampling technique is presented in this thesis. Charge sampling integrates input current instead of tracking input voltage to realize high speed and low voltage sampling. The analysis focuses on the performance of general charge sampling circuits for signal capture. The theoretical analysis here can be applied not only for the weak signal capture, but also for the no
