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Cancer testis antigens (CTAs) are of clinical interest as biomarkers and present valuable targets for immunotherapy. To comprehensively characterize the CTA landscape of non-small-cell lung cancer (NSCLC), we compared RNAseq data from 199 NSCLC tissues to the normal transcriptome of 142 samples from 32 different normal organs. Of 232 CTAs currently annotated in the Caner Testis Database (CTdatabas
A 76-year-old man presented with cognitive symptoms, followed by headache and weakness of the lower limbs and left arm. The clinical course was progressive but fluctuating. On magnetic resonance imaging (MRI), a contrast-enhancing lesion 1 cm in diameter was seen in the left temporal lobe. This lesion became attenuated and a new contrast-enhancing lesion 1 x 2 cm was seen in the left frontal lobe
Following spinal cord injury (SCI) a series of anatomical and functional plastic changes occur in the spinal cord, including reorganization of the spinal neuronal network, alteration of properties of interneurons and motoneurons as well as up- or down-regulation of different neurotransmitter receptors. In mammalian spinal cord, one of the important neurotransmitters, serotonin (5-HT), plays an ess
In this paper we call into question the relationship between development, inequality and territory in the current context of globalization and within the framework of public policies designed, supposedly, to benefit those social actors with fewer resources. In order to do this, we focus on a case study in the northeast of the province of Misiones, Argentina. Here tobacco production, forestry and a
In diverse countries of the continent, environmental transformations -and the injustices connected- have traditionally been studied in the case of extractive industries, such as mining, oil or agriculture. However, in the present study we want to discuss these concerns in the context of mega-projects that are commonly considered part of a “sustainable development”. Renewable, clean or green techno
Ca2+-sensor proteins are generally implicated in insulin release through SNARE interactions. Here, secretagogin, whose expression in human pancreatic islets correlates with their insulin content and the incidence of type 2 diabetes, is shown to orchestrate an unexpectedly distinct mechanism. Single-cell RNA-seq reveals retained expression of the TRP family members in β-cells from diabetic donors.
In my presentation I will seek to describe, analyse and reflect on the challenges and opportunities of agroecology in the province of province of Misiones, Northeaster Argentina, and the territorial dynamics generated from the promotion of a particular way to produce and trade food. My focus will be on the discourses and practices around food production for family consumption and for local markets
In Russland leben Millionen von zentralasiatischen Arbeitsmigranten. Aus Sprach-, Informations- oder Geldmangel verfügen sie oft über keine Papiere und sind in der Schattenwirtschaft tätig, wo sie Missbräuchen ausgesetzt sind. Deshalb haben sie informelle Integrationsstrukturen entwickelt, bei denen häufig Schutzgelderpresser die Interessen der Migranten vertreten.
Year-to-year variations in crop yields can have major impacts on the livelihoods of subsistence farmers and may trigger significant global price fluctuations, with severe consequences for people in developing countries. Fluctuations can be induced by weather conditions, management decisions, weeds, diseases, and pests. Although an explicit quantification and deeper understanding of weather-induced
Knowledge of the material in the ATLAS inner tracking detector is crucial in understanding the reconstruction of charged-particle tracks, the performance of algorithms that identify jets containing b-hadrons and is also essential to reduce background in searches for exotic particles that can decay within the inner detector volume. Interactions of primary hadrons produced in pp collisions with the
Measurements of distributions of charged particles produced in proton–proton collisions with a centre-of-mass energy of 13 TeV are presented. The data were recorded by the ATLAS detector at the LHC and correspond to an integrated luminosity of 151 μ b - 1. The particles are required to have a transverse momentum greater than 100 MeV and an absolute pseudorapidity less than 2.5. The charged-particl
The elliptic flow of electrons from heavy-flavour hadron decays at mid-rapidity (|y| < 0.7) is measured in Pb-Pb collisions at sNN=2.76 TeV with ALICE at the LHC. The particle azimuthal distribution with respect to the reaction plane can be parametrized with a Fourier expansion, where the second coefficient (v2) represents the elliptic flow. The v2 coefficient of inclusive electrons is measured in
The elliptic, triangular, quadrangular and pentagonal anisotropic flow coefficients for π±, K± and p + p ¯ in Pb-Pb collisions at sNN=2.76 TeV were measured with the ALICE detector at the Large Hadron Collider. The results were obtained with the Scalar Product method, correlating the identified hadrons with reference particles from a different pseudorapidity region. Effects not related to the comm
Measurements of the top-antitop quark pair production charge asymmetry in the dilepton channel, characterized by two high-pT leptons (electrons or muons), are presented using data corresponding to an integrated luminosity of 20.3 fb-1 from pp collisions at a center-of-mass energy s=8 TeV collected with the ATLAS detector at the Large Hadron Collider at CERN. Inclusive and differential measurements
Effects of surfactants on protein adsorption are reviewed. Differences between removal of preadsorbed proteins (elutability) and competitive adsorption are discussed and simple models are suggested. It can be concluded that surfactants may interact through solubilization or replacement mechanisms depending on surfactant- surface interactions and surfactant- protein binding. Solubilization requires
Keynote presentation about recent developments within the street art world which could lead to a situation where the otherwise constant flux of visual expressions in the street may come to a halt.
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses proton-proton collision data corresponding to an integrated luminosity of 3.2 fb-1 at s=13 TeV collected in 2015 with the ATLAS detector at the Large Hadron Collider. Events are required to have at least one jet with a transverse momentum above 250 GeV and
