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The homolytic cleavage of the organometallic Co-C bond in vitamin B-12-dependent enzymes is accelerated by a factor of similar to 10(12) in the protein compared to that of the isolated cofactor in aqueous solution. To understand this much debated effect, we have studied the Co-C bond cleavage in the enzyme glutamate mutase with combined quantum and molecular mechanics methods. We show that the cal
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Backgrounds and aims: To investigate mortality, determinants of mortality, and time until death among elderly subjects receiving public long-term care. Methods: This study comprises 626 respondents (age: 65-98 years). Data were collected for two cohorts (2001 and 2002). Cox regression analysis was used to identify determinants of mortality. Those who died and those who did not die were compared by
Human height is a classic, highly heritable quantitative trait. To begin to identify genetic variants influencing height, we examined genome-wide association data from 4,921 individuals. Common variants in the HMGA2 oncogene, exemplified by rs1042725, were associated with height (P= 4x10(-8)). HMGA2 is also a strong biological candidate for height, as rare, severe mutations in this gene alter body
High-spin states of the neutron deficient nucleus Nb-88 have been studied following the reaction Fe-56 (Cl-35, 2pn) Nb-88 at 120 and 123 MeV bombarding energy. Neutron gated and pure gamma gamma-coincidences were measured with a neutron-gamma gamma-coincidence setup; in addition gamma gamma-coincidences were detected with the OSIRIS-cube at the Cologne tandem accelerator. Via the analysis of gamma
A total of 12 patients previously treated for acute hepatitis of unknown aetiology were retrospectively found to be anti-hepatitis E virus (HEV) IgG-positive. Four patients were anti-HEV IgM- and IgG-positive consistent with an acute HEV infection. All 4 had travelled to or were immigrants from HEV-endemic countries. One anti-HEV IgM-negative patient seroconverted from anti-HEV IgG-negative to pos
The upper limit of flammability of hydrogen in air, oxygen, oxygen-helium, oxygen-neon, oxygen-argon and oxygen-carbon dioxide mixtures was measured at room temperature and pressures between 0.97 and 29 atm in two cylindrical bombs with volumes of 1.5 and 5.2 liters. The limit in ternary mixtures was determined in 20%, 40%, 60% and 80% helium, 20% neon and argon and 10% carbon dioxide concentratio
Background Sensory information from mechanoreceptors in the skin, muscles, tendons, and joint structures plays an important role in joint stability. A joint injury can lead to disruption of the sensory system, which can be measured by proprioceptive acuity. When evaluating proprioception, assessment tools need to be reliable. The aim of this study was to assess the test-retest reliability of a de
Two-hundred ninety five patients with the antiphospholipid syndrome (APS) were studied for the presence of antibodies against six anti-beta2GPI-related peptides Abs. The prevalence of a wide spectrum of clinical and laboratory parameters of APS was evaluated in all patients, and correlated with the presence of each anti-beta2GPI peptide antibody. The rates of the various antipeptides Abs ranged fr
Filmrecension av Robert Altmans Gosford Park
Otryggheten vid kollektivtrafikresor är relativ hög. Drygt hälften av vaneresenärerna har känt sig otrygga i samband med en kollektivtrafikresa. Även om de allra flesta endast har känt otrygghet ibland, kan detta leda till att människor reser mindre kollektivt än de önskar; att de hellre kör bil eller att deras rörlighet minskar. För att minska otryggheten vid kollektivtrafikresor kan det vara nöd
UPPLEVELSER AV SVENSK FILM offers a broad understanding of Swedish cinema during the years between 1985 and 2000. The dissertation focuses on those Swedish films that have been given a wide distribution, i.e. films that in many cases can be considered popular films. (Films that have only obtained a marginal position in the cinemas have not been included.) The films studied attract an average of 2,
