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Background: Embolic strokes of undetermined source comprise up to 20% of ischemic strokes. The stroke recurrence rate is substantial with aspirin, widely used for secondary prevention. The New Approach riVaroxaban Inhibition of Factor Xa in a Global trial versus ASA to prevenT Embolism in Embolic Stroke of Undetermined Source international trial will compare the efficacy and safety of rivaroxaban,

White matter hyperintensity (WMH) burden is a critically important cerebrovascular phenotype linked to prediction of diagnosis and prognosis of diseases, such as acute ischemic stroke (AIS). However, current approaches to its quantification on clinical MRI often rely on time intensive manual delineation of the disease on T2 fluid attenuated inverse recovery (FLAIR), which hinders high-throughput a

Some possible errors in determining the gravity anomalies are discussed. Such errors may be caused by an inaccurate calibration of the gravimeter used in an airborne survey system. An approach based on the wavelet decomposition is proposed for its additional calibration with the use of flight data obtained during repeated flights.

State redress for abuse and neglect in children’s homes has been debated in all Scandinavian countries since early 2000s. In Sweden, an official apology was issued in 2011, and a temporary law enabled Swedish care leavers to apply for compensation of SEK 250,000 during 2013 and 2014. In Denmark, proposals for an official apology have repeatedly been turned down in Parliament. In this article, I co

New software vulnerabilities are published daily.Prioritizing vulnerabilities according to their relevance to the collection of software an organization uses is a costly and slow process.While recommender systems were earlier proposed to address this issue, they ignore the security of the vulnerability prioritization data.As a result, a malicious operator or a third party adversary can collect vul

Objective. The aim of this study was to examine the occurrence of repair in a cohort of conventionally treated patients with early rheumatoid arthritis over 8 years.Methods. There were 395 patients included in the BARFOT study having radiographs of hands and feet at inclusion, and at 1, 2, 5, and 8 years, which were chronologically scored for erosions by the Sharp/van der Heijde method. An erosion

OBJECTIVES:The aim of this study was to apply a previously published method for evaluating radiographic progression, namely, predicted vs. observed radiographic progression in early rheumatoid arthritis (POPeRA), to the Swedish pharmacotherapy (SWEFOT) trial.METHOD:In SWEFOT, 487 patients with eRA were given methotrexate (MTX), and non-responders were randomized to group A [triple therapy: MTX+sul

In this paper, we present a fast algorithm of time synchronization between User Equipment (UE) and Base Station (BS) which is suitable for Long Term Evolution (LTE) Random Access Channel (RACH). The algorithm reduces the complexity more than 1.5 times. Further, if the SNR is above a threshold, the algorithm allows to extremely reduce the complexity of synchronization more than 3 times. The present

Patients with alkaptonuria lack homogentisate 1,2-dioxygenase leading to retention of homogentistic acid (HGA) in body fluids and eventually to tissue deposition of oxidation products, giving rise to the clinical picture of ochronosis. Ascorbic acid is a known inhibitor of the enzyme which catalyses the oxidation of homogentisic acid (HGA) to the polymer with affinity for collagen and was used in

Twenty-one of 25 consecutive primary fibromyalgia or fibrositis patients, identified during a 5-year period in a tertiary care day-ward for pain syndromes, were re-examined. Fifteen fulfilled criteria for fibromyalgia but unexpectedly, all cases had either psychiatric disturbance or thyroid dysfunction. Of the four patients not seen at follow-up, two had developed neurological diseases, another rh

For high-resolution massive MIMO and very large antenna arrays, wireless channel models have to scrutinize the detailed space features of the surrounding environment. Existing models such as WINNER and 3GPP are not appropriate for validating and evaluating new concepts for 4G/5G as they do not consider the spatial characteristics of the real environment. The simplified 3D shapes of simulated objec