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Obituary, Professor Barbro Klein 1938-2018.

Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we performed genome-wide analyses of circulating HDL cholesterol, LDL cholesterol, and triglyceride levels in up to 120,979 individuals of European, African, Asian, Hispanic, and Braz

We present a Monte Carlo algorithm that detects the presence of a Hamiltonian cycle in an n-vertex undirected bipartite graph of average degree delta >= 3 almost surely and with no false positives, in (2-2^{1-delta})^{n/2}poly(n) time using only polynomial space. With the exception of cubic graphs, this is faster than the best previously known algorithms. Our method is a combination of a variant o

High or low ambient temperatures pose a risk factor for the worsening or onset of psychiatric disorders. The aim of this study was to investigate the association between ambient temperature and psychiatric emergency visits in an urban region in a temperate climate. The daily number of visits to a psychiatric emergency room (PEVs) at Sahlgrenska University Hospital, Gothenburg, Sweden and the daily

We study the problem of counting the isomorphic occurrences of a k-vertex pattern graph P as a subgraph in an n-vertex host graph G. Our specific interest is on algorithms for subgraph counting that are sensitive to the maximum degree Delta of the host graph. Assuming that the pattern graph P is connected and admits a vertex balancer of size b, we present an algorithm that counts the occurrences o

Given an undirected graph and two disjoint vertex pairs s_1,t_1 and s_2,t_2, the Shortest two disjoint paths problem (S2DP) asks for the minimum total length of two vertex disjoint paths connecting s_1 with t_1, and s_2 with t_2, respectively. We show that for cubic planar graphs there are NC algorithms, uniform circuits of polynomial size and polylogarithmic depth, that compute the S2DP and moreo

We present an overview of the distributions of 11 elemental abundances in the Milky Way's (MW) inner regions, as traced by APOGEE stars released as part of the Sloan Digital Sky Survey Data Release 14/15 (DR14/DR15), including O, Mg, Si, Ca, Cr, Mn, Co, Ni, Na, Al, and K. This sample spans ∼4000 stars with R GC ≤ 4.0 kpc, enabling the most comprehensive study to date of these abundances and their

Purpose: To identify and evaluate possible causes of poor patient-reported visual function after cataract surgery. Methods: We obtained retrospective data from the Swedish National Cataract Register on patient self-assessed visual function before and after cataract surgery based on the Catquest-9SF questionnaire. We identified patients who self-reported similar or more difficulties postoperatively

Objectives: Patients with antineutrophil cytoplasmatic antibodies-associated vasculitides (AAV) exhibit higher mortality than the general population. In the current study, we assessed whether cluster affiliation based on clinical presentation might predict mortality. Methods: With case record review, the outcomes for a population-based cohort of patients diagnosed with AAV in southern Sweden (catc

Human brown fat tumors (hibernomas) display concomitant loss of the tumor suppressor genes MEN1 and AIP. In the present study, we hypothesized that the brown fat phenotype is attributed to these mutations. Accordingly, we demonstrate that silencing of AIP in human brown preadipocytic and white fat cell lines results in the induction of the brown fat marker UCP1. In human adipocytic tumors, loss of

Introduction: Central venous access devices facilitate home treatment in boys with haemophilia. These are usually fully implanted lines, referred to as ports. Caregivers are taught to manage the port using sterile techniques and maintaining patency by flushing with saline or heparin solution. National and international guidelines for the home care of ports are lacking. Aim: To evaluate if infectio

Background: The Autism Diagnostic Interview-Revised (ADI-R) is considered a first choice assessment tool in autism spectrum disorder. Nevertheless, despite its wide use in psychiatric practice and recommendations by various clinical guidelines, its interrater reliability has predominantly been confirmed in research settings by specially trained, research reliability interviewers. The reliability o

Late medieval towns have often been neglected within the urban archaeological paradigm. This article tries to discuss the medieval urbanization from the perspective of small late medieval towns in relation to other types of central places by using a regional perspective. The towns of Vimmerby and Eksjö, and the central places of Värnamo and Vetlanda in Småland are used as examples. In this region,

Denna bok är avsedd att vara en vägledning och fördjupning till utställningen Skatter i Skåneland. Boken innehåller dels en kronologisk översikt över såväl det historiska som det numismatiska skeendet i Skåneland under den tid när man där präglade mynt, och dels spännande historier kring de myntfynd som visas i utställningen. Tanken är att boken skall vara besökaren till nytta i utställningen men

This book is intended as a guide to the exhibition "Treasures in Skåneland”, providing further information. The book contains a chronological survey of general and numismatic history in Skåneland during the time when coins were minted here, as well as descriptions of the coin finds on show in the exhibition. The idea is that the book will be of use to visitors in the exhibition, while also making

Solid tumors in childhood are extremely rare entities, which are usually treated in specialized centers. Diagnosis and therapy are carried out according to a joint European protocol, whereby the pathological evaluation and therapy are carried out according to international guidelines. For the correct diagnosis and/or therapy of most tumors, analysis of specific genetic changes is mandatory; theref