Kan simuleringsmodeller förbättra diagnostik av förändringar i höftens anatomi hos barn? Anatomiska förändringar i höftleden kan drabba barn i olika åldrar. En följd av detta kan vara att belastningen i höften ändras, vilket kan öka risken för artros. Att undersöka och behandla förändringar i höftens anatomi hos barn är viktigt för att förhindra komplikationer senare i livet. Höftleden är en viOsteoarthritis is a degenerative disease that will cause pain and stiffness in the joint if not treated. One cause of early osteoarthritis in the hip joint is pediatric hip deformities. Hip deformities can occur in different stages of childhood and cause the bones to be misshapen or the hip joint to be dislocated. This thesis aimed to build subject-specific computer models of the hip joint to fi

Att analysera livets biokemi, kemin bakom biologiska processer, är viktigt för att få en förståelse av livets mekanismer, speciellt för små längdskalor. Biokemin hos olika typer av celler skiljer sig åt, vilket kan användas för att t.ex skilja mellan elakartade och icke-elakartade tumörer. Vilka ämnen som finns i en cell kan bli identifierade via deras respektive absorptionspektrum. Ett absorptionA hyperspectral image may be decomposed into component spectra and their distri- bution in the image to simplify analysis by revealing underlying patterns and reducing the dimensionality of the image; this may be achieved by the algorithm MCR-ALS. However, the algorithm is time consuming, but could be accelerated by a data re- duction. Data reduction can be done by using a clustering method. In th

The Venezuelan equine encephalitis virus (VEEV) is a highly infectious alphavirus responsible for severe outbreaks and epidemics in the Americas. The nonstructural protein 2 (nsP2) cysteine protease plays a fundamental role in the VEEV replication process, and is therefore, an attractive drug target for structure-based drug design using x-ray crystallography. Generating protein crystals of suffi

Duplikationen av långvåglängdkänsliga opsiner i fjärilar Människor och många andra djur upplever världen omkring de i färg, och för att kunna ha ett färgseende krävs det att man kan detektera ljus av olika våglängder. Människor, och många andra djur, kan uppfatta ljus inom det synliga spektrumet, vilket sträcker sig från blått ljus som är av kortare våglängder till rött ljus som är av längre våglBackground: Color vision is enabled by visual opsins, a class of G-protein coupled receptors expressed in the eye. How well an organism discriminates color depends notably on the number of opsins, and their spectral sensitivity when bound to a light-sensitive chromophore (retinal). Spectral phenotypes have evolved convergently multiple times owing to opsin gene losses and duplications, both in ver

Araceae is one of the most abundant species families in South America with over 2200 species across the continent, yet it has not been given much attention in ecological investigations. I analysed the species diversity and abundance of araceans along an altitudinal transect between 400 and 2350 m altitude. The transect, made up of 7 different sites, was located in the Cloud forests of the Ecuadori

The impact of climate change is increasingly being investigated over elevational gradients as they provide natural laboratories to study how species of plants and animals respond to changes in temperature, precipitation and other factors. Ferns are especially sensitive to air humidity and temperature and can therefore serve as potentially useful bioindicators. To better understand how species comm

Förhindra antibiotikaresistens – börja övervaka den! För snart hundra år sedan upptäcktes penicillin – ett antibiotikum som sedan dess har räddat miljontals människor från bakterieinfektioner. Idag ser vi hur antibiotika blir helt verkningslösa då bakterierna i ökande takt utvecklar resistens mot dem. Inom en snar framtid kan vi befinna oss i en era där vi återigen dör av infektioner som tidigar

Due to their aberrant growth behavior, cancer cells maintain and depend on aerobic glycolysis even in the presence of physiological oxygen levels to provide building blocks for cell proliferation. This and other dependencies in the metabolism of cancer cells have emerged as promising targets for therapy development. However, metabolic interventions also target highly proliferating cells of the imm

Having access to dense reconstruction of ongoing building constructions provides insight into the building process and could serve as both a tool for error detection and documentation of the actual outcome. In this thesis, Spot, the quadruped robot designed by Boston Dynamics is evaluated as a platform for site inspection. The result of the thesis was a prototype system built on top of the ROS fra

The NEO model, developed by Lindström (2019) for paperboard, is a non-linear material model that utilizes empirically based constitutive relations with switches to mimic elastic-plastic responses. Due to the explicit definition of the constitutive relations, the NEO model does not require a constitutive equilibrium loop. This, in addition to modeling flexibility from the switches, poses the NEO mo

The circulating fluidised bed boiler (CFB) consists of developing the combustion of a mass of fuel, in this case biomass, within a bed of particles in suspension, which have been fluidised by an ascending air current. Combustion occurs in a controlled manner throughout the entire furnace at temperatures around 850 ºC, which is lower than in conventional boilers, reducing NOx emissions. However, NO

This thesis examines the challenges that women human rights defenders (WHRDs) in Bangladesh are experiencing in a period of shrinking civic space. It further focuses on how perceptions guide their chosen strategies. Applying political opportunity theory, drawing from social movements research, it explores the structural changes in the political system and how it impacts civil society action. Thus,

Hamilton tells the story of the life and career of Alexander Hamilton, an immigrant who came to America at a young age and grew up to be a founding father as well as the first Treasury Secretary of the United States of America and the face of the US ten-dollar bill. Since premiering in 2015, the hip-hop-musical grew into a popular culture phenomenon, resonating with people all over the world while

The combustion of lignite coal for energy production significantly contributes to Germany’s greenhouse gas emissions, leading climate justice activists to advocate for an immediate coal exit. Workers of the lignite industry strongly oppose this as they worry about the structural decline of mining regions and their financial security. The concept of Just Transition is increasingly employed to bridg

Gullvivor älskar motionsspåret i Skrylle, Skåne En av vårens första tecken är de växter vars blommor klär marken med vackra färger. En av dessa växter är gullviva (Primula veris) som känns igen genom sina starkt gula blommor och ljusgröna rosettblad. I Sverige är gullvivan en skyddad art och den lokala populationen har minskat under en lång tid. Förminskingenen beror antagligen på markförsurning,In 2000, a 5-kilometer-long exercise path called Elljusspåret was constructed in Skrylle, Sweden. Excavations of the soil on the right side of the path were made to install lampposts. A large number of Primula veris emerged from the excavated soil. This re-evaluation investigates if the P. veris population still favours the excavated side and if it could be due to change in the soil horizon chemis

The internet brings a multitude of opportunities for information access, communication, and mobilization. Many studies point to the democratizing effect of the internet in that it increases political participation among citizens. However, much of this evidence is produced on a Western context where the penetration of the internet is well-established. This thesis examines the effect of internet use

Small scale renewable energy systems (SSRES) serve as a potential solution to decrease energy poverty, increase water and food security, and a potential climate change adaptation (CCA) strategy. This thesis investigates the diffusion of such systems amongst indigenous Wayuu communities in La Guajira, Colombia, through Roger's Diffusion Theory. Subsequently, a Water-Energy-Food Security Nexus a

Since the 1980s, community seed banks (CSBs) have been established around the world to conserve and improve access to indigenous seed for smallholder communities and contribute to food and seed sovereignty. However, after the withdrawal of external support, these CSB initiatives often collapse. Using a qualitative, comparative case study design, this study provides an in-depth analysis of CSBs est

Can Crows and Ravens Tell Selfish and Generous Humans Apart? Imagine that you observe two people at the store reaching for the two last packages of their favourite cookies. The person that arrived last at the spot asks the first one for a package. In the first scenario, the human that arrived first acts generously and gives one package, while in the alternative scenario, the human acts selfishly