This article provides a diverse range of insights into the question of how sociology can and should contribute to research on climate change. It takes an unconventional and unique approach to doing so, through a stylized conversation between the authors, which is based on an open-ended focus group discussion. The conversation illuminates different perspectives on if and how to research climate cha

The depletion of disruptive variation caused by purifying natural selection (constraint) has been widely used to investigate protein-coding genes underlying human disorders 1–4, but attempts to assess constraint for non-protein-coding regions have proved more difficult. Here we aggregate, process and release a dataset of 76,156 human genomes from the Genome Aggregation Database (gnomAD)—the larges

Context. The third Gaia Data Release (DR3) provided photometric time series of more than 2 million long-period variable (LPV) candidates. Anticipating the publication of full radial-velocity data planned with Data Release 4, this Focused Product Release (FPR) provides radial-velocity time series for a selection of LPV candidates with high-quality observations. Aims. We describe the production and

Industrial symbiosis, a concept derived from industrial ecology, emphasizes the collaborative and synergic production among industries. The particular focus is on cyclical flows of resources (material, energy, water, and/or by-products), in order to minimize impacts on the environment. In this way, an industry could reuse the discarded resources of another industry as an input to production. Essen

Reverse Logistics Networks (RLNs) have grown in importance after return policies became compulsory. Lately, questions have been raised whether they effectively decrease environmental impact: efforts to optimize the eco-efficiency of RLNs through minimizing costs and emissions were deployed, but results are not advancing with the necessary speed. Alternatively, the eco-effectiveness ("doing the rig

Purpose: to propose two enhancements for the European Union’s Circular Material Use rate (CMU): inclusion of Preparation for Reuse (PfR) flows and enhanced reproducibility across lower levels of analysis. Methods: PfR flows are added to the material flow Sankey Diagram. The Local Circularity Rate (LCR) is based in the CMU and is broke down in three waste-related ratios: recovered-to-treated (RCV-t

Municipal Solid Waste Management is yet to be eco-effectively performed, especially in developing countries. In Brazil, a considerable fraction of waste has been improperly landfilled, generating environmental, social and economic problems. In 2018, the government of the state of Paraná released a revised version of its waste management plan, defining improvement strategies to be gradually impleme

The challenge to develop sustainable products increases as resources becomes scarcer. Lifecycle Assessment (LCA) and Ecodesign have emerged to diminish product environmental impact from material gaining to disposal. LCA methods and tools, however, were not conceived to spur product design activities and decisions towards sustainable End-of-life (EoL) product conception, while Ecodesign requires ma

Sustainable supply chain design can be performed using optimisation strategies for minimising environmental impacts while maximising profit. It is not clear how such strategies influence the resilience of a supply chain – its ability to handle disturbances without compromising its function. This research used the ecosystem network analysis (ENA) to evaluate the resilience during the design of a su

Anthropocentrism and disciplinary research have not led to effective solutions to sustainability problems. A shift is required towards biocentric, transdisciplinarity-based solutions, to mitigate rebound effects and unintended, negative effects. In the field of Sustainable Supply Network Design, such shift implies on developing resilient solutions that maximize environmental benefits instead of mi

One of the best opportunities to deliver sustainable principles is during the product development process. To be considered truly sustainable, a product must be designed respecting three dimensions: economic, environmental and societal, in a systemic approach. From this perspective, this paper aims to overview sustainable product design and interfaces with its supporting processes, taking advantag

INTRODUCTION: Reporting of sex and gender analysis in medical research has been shown to improve quality of the science and ensures findings are applicable to women and men. There is conflicting evidence on whether efforts by funding agencies and medical journals to encourage reporting of sex and gender analysis has resulted in tangible improvements. This study mapped the inclusion of sex and gend

Fundamental bounds on the performance of monochromatic scattering-cancellation and field-zeroing cloaks made of prescribed linear passive materials occupying a predefined design region are formulated by projecting field quantities onto a sub-sectional basis and applying quadratically constrained quadratic programming. Formulations are numerically tested revealing key physical trends as well as adv

Considerable time is often spent optimizing antennas to meet specific design metrics. Rarely, however, are the resulting antenna designs compared to rigorous physical bounds on those metrics. Here, we study the performance of optimized planar meander line antennas with respect to such bounds. Results show that these simple structures meet the lower bound on the radiation quality factor (Q-factor)