Investigating recombinant transaminase stability with cofactor variations and enzyme immobilization
Amine transaminases are valuable biocatalysts in the pharmaceutical industry for the production of chiral amines. Their high regioselectivity and inherent regeneration of cofactor pose them as a greener alternative to the chemical synthesis. However, their application is hampered by their limited stability and narrow substrate scope and product inhibition. Recently, a stable tetrameric amine trans
