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In this paper we present the first investigation of the C–N coupling reaction between N-tosylhydrazones including O-peracylated 2,6-anhydro-aldose tosylhydrazones and 1H-1,2,3-triazoles under catalyst-free conditions. This transformation is characterized by relatively mild thermal conditions, high regioselectivity in favor of 2,4-disubstituted 2H-1,2,3-triazoles and broad functional group tolera

Research suggests that individuals often overlook beneficial subtractive strategies when solving problems. Subtractive strategies, which include reducing demand for goods and services (e.g., reducing car use), have a high climate mitigation potential. Yet, these may be systematically overlooked in favor of additive strategies like adopting new technologies (e.g., buying an electric car). This Regi

Offering supports for young adults with mental health problems in their educational and vocational pursuits promotes well-being, social inclusion, and self-sufficiency. It is therefore important that welfare actors offer services to this group. However, in Sweden, with a tradition of local self-governance and municipal autonomy, decisions regarding which services to offer may depend on perceptions

Haploblocks are regions of the genome that coalesce to an ancestor as a single unit. Differentiated haplotypes in these regions can result from the accumulation of mutational differences in low-recombination chromosomal regions, especially when selective sweeps occur within geographically structured populations. We introduce a method to identify large well-differentiated haploblock regions (LHBRs)

Introduction: Residual cognitive deficits are commonly reported by individuals in remission from depression, often affecting daily life functioning and mental health. To provide tailored and personalized cognitive enhancement interventions for this population, there is a need for a better understanding of the characteristics of those who benefit from such interventions. Therefore, this study aimed

Objective: To evaluate the causal effect of genetically predicted serum urate (SU) levels on the risk of overall and major site-specific cancers in individuals of European ancestry, using Mendelian randomization (MR) analysis. Method: Data from two population-based cohorts from southern Sweden, the Malmö Diet and Cancer Study (MDCS) and Malmö Preventive Project (MPP), and summary-statistics data f

Objectives Early detection of neurosensory injury among workers exposed to hand-arm vibration is crucial. The aim of our study was to evaluate the diagnostic test performance of clinical point-of-care testing using a tuning fork and temperature rollers in relation to vibrotactile and thermal quantitative sensory testing. Methods We recruited 225 vibration-exposed workers who underwent clinical poi

Understanding the structure of metal-ligand complexes is essential for catalyst design, materials development, and biochemical modeling. Metal carbonyls are especially relevant due to their diverse structures and electronic features. Here, we benchmarked seventeen density functionals (B3LYP, BP86, CAM–B3LYP, M06, M06L, PBE, PBE0, r2SCAN, r2SCAN–3c, revPBE, revTPSS, RPBE, TPSS, TPSS0, TPSSh, (Formu

OBJECTIVES: This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of acupuncture for the treatment of infantile colic.

The Paris Agreement necessitates global net-zero emissions by mid-century, including steel industry emissions that currently amount to about 7% of global energy system emissions. In this article we review the literature on steel decarbonization. Steel industry emission mitigation measures include reduced demand through materials efficiency, increased high-quality recycling, and decarbonization of

This paper presents an integrated conodont biostratigraphy and carbon isotope chemostratigraphy for the Cambrian-Ordovician transition in western Zhejiang, southeast China. Eight conodont zones can be recognized, in ascending order the Westergaardodina cf. calix-Prooneotodus rotundatus, Proconodontus, Eoconodontus, Cordylodus proavus, Cordylodus intermedius, Cordylodus lindstromi, Cordylodus angul

Background: Employment rates are lower in adults with cerebral palsy (CP). Even though reduced manual ability is associated with limitations in daily activities, it is unclear whether employment rates are associated with manual ability in adults with CP. Objective: To analyze regular employment and employment rates (hours/week) in adults with CP and estimate their associations with manual ability

This chapter focuses on how to apply salutogenesis in practice in the context of health care, especially when designing interventions. The foundation for implementation is to understand and apply the core principles of salutogenesis and health promotion, hereby building capacity and strength in all involved, i.e.: the patients, participants, health professionals and relatives. The key salutogenic

Bakgrund: Hemlöshet utgör en komplex global samhällsutmaning. Individuella, politiska och sociokulturella faktorer begränsar hemlösa personers möjligheter att utöva sin rätt till aktivitet och hälsa i vardagen. Internationella studier indikerar att aktivitetsbaserade åtgärder kan vara gynnsamma för målgruppen, men mer samlad kunskap behövs för att stödja framtida studier som undersöker hur svenskaBackground: Homelessness constitutes a complex global societal challenge. Individual, political and socio-cultural factors limit homeless persons from exercising their right to activity and health in everyday life. International studies show that the use of occupation-based interventions may benefit the target group. Further evidence is needed to inform future studies investigating how Swedish occ

I denna uppsats undersöks hur upphovsrättsliga avtal bör tolkas enligt den avkunnade dom som presenterades i referatet NJA 2025 s. 162, ”Deckarserien”. De centrala frågorna som behandlas i uppsatsen är hur specifikationsprincipen har tillämpats tidigare och om Deckarserien innebär något nytt för hur upphovsrättsliga avtal bör tolkas eller om rättsfallet endast innebär ett förtydligande av gällandeThis thesis examines how copyright agreements should be interpreted in light of the Swedish Supreme Court’s judgment in NJA 2025 p. 162, Deckarserien. The central questions that the thesis explores are how the specification principle previously has been applied in Swedish courts and whether Deckarserien introduced anything new regarding the interpretation of copyright agreements, or whether the ca

Feel overwhelmed but realise the need to understand what's going on? Academic analytical frameworks can help.European countries, and Denmark in particular, are scrambling to respond to threats from US officials over the future of Greenland.Having successfully taken out the leadership of Venezuela in a raid on January 3, an emboldened US government is talking about simply taking Greenland for itsel

Inclusive urbanisation is being promoted in development discourse, and a scholarly debate is emerging, but the conceptualisation and empirical understanding of this process should be placed in relation to urbanisation trends. In sub-Saharan Africa more than a quarter of the urban population lives in small towns. These are predicted to experience the most rapid population growth in the coming decad