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A stacking ensemble deep learning approach to cancer type classification based on TCGA data

Cancer tumor classification based on morphological characteristics alone has been shown to have serious limitations. Breast, lung, colorectal, thyroid, and ovarian are the most commonly diagnosed cancers among women. Precise classification of cancers into their types is considered a vital problem for cancer diagnosis and therapy. In this paper, we proposed a stacking ensemble deep learning model b

Risk factors for overweight and obesity among women of reproductive age in Dar es Salaam, Tanzania

Background: Overweight and obesity have increased considerably in low- and middle-income countries over the past few decades, particularly among women of reproductive age. This study assessed the role of physical activity, nutrient intake and risk factors for overweight and obesity among women in Dar es Salaam, Tanzania. Methods: We conducted a cross-sectional survey among 1004 women aged 15–49 ye

Do women enrolled in PMTCT understand the recommendations : A case study from Kilimanjaro

Introduction: Prevention of mother-to-child transmission (PMTCT) remains a cornerstone of HIV prevention and control efforts. It is vital that the beneficiaries of PMTCT programs understand PMTCT recommendations, especially since their adherence to recommendations is key to successful PMTCT. There have been several major changes in PMTCT recommendations, and many women have encountered different r

Predictors of singleton preterm birth using multinomial regression models accounting for missing data : A birth registry-based cohort study in northern Tanzania

Background Preterm birth is a significant contributor of under-five and newborn deaths globally. Recent estimates indicated that, Tanzania ranks the tenth country with the highest preterm birth rates in the world, and shares 2.2% of the global proportion of all preterm births. Previous studies applied binary regression models to determine predictors of preterm birth by collapsing gestational age a

Knowledge, attitude, and practice of cervical cancer screening among women living with HIV in the Kilimanjaro region, northern Tanzania

Background: Cervical cancer is the fourth most common cancer globally among women in incidence and mortality. Women living with HIV (WLHIV) are disproportionately at a higher risk of developing the disease. Aim: To determine the knowledge, attitude, and practice of cervical cancer screening among WLHIV in the Kilimanjaro region, northern Tanzania, following the integration of these services in rou

Feasibility and acceptability of human papillomavirus self-sampling in a semi-urban area in northern Tanzania

Objective: To assess the feasibility and acceptability of HPV self-sampling in Arusha region, northern Tanzania, because the ability for women to self-collect HPV samples can help reduce the number of health facility visits and improve cervical cancer screening coverage rates. Methods: We conducted a facility- and community-based cross-sectional study among 350 women aged 25–55 years in Arumeru di

Depression and associated factors among geriatric population in Moshi district council, Northern Tanzania

Background: Depression in the elderly population has been identified as a significant public health problem associated with adverse outcomes such as decreased quality of life, cognitive decline, and increased rates of suicide. We aimed to determine the prevalence and factors associated with depressive symptoms among geriatric population in Moshi district council, northern Tanzania. Methods: This c

Community engagement in COVID-19 prevention: Experiences from Kilimanjaro region, northern Tanzania

Prevention of exposure to the COVID-19 virus in the general population is an essential strategy to slow community transmission. This paper shares the experiences and challenges of community engagement in COVID-19 prevention in the Kilimanjaro region, Northern Tanzania implemented by our team from the Institute of Public Health (IPH), Kilimanjaro Christian Medical University College (KCMUCo) in col

Prediction of perinatal death using machine learning models : A birth registry-based cohort study in northern Tanzania

Objective We aimed to determine the key predictors of perinatal deaths using machine learning models compared with the logistic regression model. Design A secondary data analysis using the Kilimanjaro Christian Medical Centre (KCMC) Medical Birth Registry cohort from 2000 to 2015. We assessed the discriminative ability of models using the area under the receiver operating characteristics curve (AU

Prevalence of and factors associated with early initiation of breastfeeding among women with children aged < 24 months in Kilimanjaro region, northern Tanzania : A community-based cross-sectional study

Background: Early initiation of breastfeeding offers nutritional and immunological benefits to the newborn, which is critical for health and survival. Understanding factors associated with timely initiation of breastfeeding is crucial for healthcare providers and policy-makers. This study aimed to assess the prevalence and factors associated with early initiation of breastfeeding among mothers wit

Prevalence and factors associated with timely initiation of breastfeeding in Kilimanjaro region, northern Tanzania : A cross-sectional study

Background: The World Health Organization (WHO) recommends early initiation of breastfeeding within 1 h as it confers many benefits to the child and prevents neonatal mortality. This study aimed to determine the prevalence and factors associated with timely initiation of breastfeeding in the Kilimanjaro region, northern Tanzania. Methods: We analyzed secondary data for 866 participants from a popu

Internet addiction and associated factors among medical and allied health sciences students in northern Tanzania : A cross-sectional study

Background: Internet addiction is one of the fast-growing addictive behaviors and is a significant public health problem affecting a large number of people worldwide. Excessive use of the internet among university students increases their risk of internet addiction and related negative consequences. This study aimed to determine the prevalence and factors associated with internet addiction among m

Trends and predictors of changes in modern contraceptive use among women aged 15-49 years in Tanzania from 2004-2016 : Evidence from Tanzania Demographic and Health Surveys

Modern contraceptive use provides opportunities for women and couples to achieve optimal child spacing, achieve desired family size and reduce unsafe abortions. Despite these facts, modern contraceptive prevalence rate (mCPR) in Tanzania remains as low as 32%. This study aimed to determine trends and factors associated with changes in modern contraceptive use among women of reproductive age in Tan

Predictors of perinatal death in the presence of missing data : A birth registry-based study in northern Tanzania

Background More than five million perinatal deaths occur each year globally. Despite efforts put forward during the millennium development goals era, perinatal deaths continue to increase relative to under-five deaths, especially in low- A nd middle-income countries. This study aimed to determine predictors of perinatal death in the presence of missing data using birth registry data from Kilimanja

Factors associated with mental distress among undergraduate students in northern Tanzania

Background: Mental distress is a major public health problem which includes anxiety, depression and somatic symptoms such as sleeping problems, fatigue and headache. University students are consistently reported to have higher levels of mental distress compared to the general population. Although university students with mental distress have significantly impaired cognitive functioning, learning d

Incidence and recurrence risk of low birth weight in Northern Tanzania : A registry based study

Background Low birth weight (LBW) is an important indicator of newborn survival. It is associated with higher risk of morbidity, mortality and long-term health consequences. Little has been done on incidence and recurrence risk of LBW in developing countries including Tanzania. This study aimed to determine the incidence and recurrence risk of LBW among women who delivered at Kilimanjaro Christian

Risk factors for inappropriate blood requisition among hospitals in Tanzania

Background Blood is a critical aspect of treatment in life saving situations, increasing demand. Blood requisition practices greatly effect sufficient supply in blood banks. This study aimed to determine the risk factors for inappropriate blood requisition in Tanzania. Methods This was a cross sectional study using secondary data of 14,460 patients’ blood requests from 42 transfusion hospitals. Pr

Prevalence, awareness and factors associated with hypertension in North West Tanzania

Background: Hypertension is a public health problem, and yet few people are aware of it and even fewer access effective treatment. With the ongoing demographic transition in many parts of Sub-Saharan Africa, people are changing from rural, manual work to urban lifestyles, hence the risk of hypertension increases. Objective: This study aimed at determining the prevalence, awareness and risk factors

Physical activity and associated factors from a cross-sectional survey among adults in northern Tanzania

Background: Insufficient physical activity (PA) is a major contributing factor in the growing problem of non-communicable diseases (NCDs) in urban and rural Sub-Saharan Africa. This study aimed to determine PA and associated factors among adults in Northern Tanzania. Methods: We analyzed secondary data from a cross-sectional serological survey nested within the Magu health and demographic sentinel

Individual and contextual factors associated with appropriate healthcare seeking behavior among febrile children in Tanzania

Introduction: Fever in malaria endemic areas, has been shown to strongly predict malaria infection and is a key symptom influencing malaria treatment. WHO recommended confirmation testing for Plasmodium spp. before initiation of antimalarials due to increased evidence of the decrease of morbidity and mortality from malaria, decreased malaria associated fever, and increased evidence of high prevale