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Lévy imaging of elastic scattering and proton hollowness at 13 TeV

The shape of elastic differential cross section within and beyond the diffractive cone at 13 TeV pp collision energy has been shown to be precisely described by the Lévy series expansion in whole available range of momentum transfers. This way, the crucial information about the real and imaginary parts of the elastic amplitude has been obtained resulting in precision reconstruction of the proton i

Multi-peaked signatures of primordial gravitational waves from multi-step electroweak phase transition

The first-order electroweak phase transition in the early universe could occur in multiple steps leading to specific multi-peaked signatures in the primordial gravitational wave (GW) spectrum. We argue that these signatures are generic phenomena in multi-scalar extensions of the Standard Model. In a simple example of such an extension, we have studied the emergence of reoccuring and nested vacuum

A complete update of ε0/ε in the standard model

The recent release of improved lattice data has revived again the interest on precise theoretical calculations of the direct CP-violation ratio ε0/ε. We present a complete update of the Standard Model prediction [1,2], including a new re-analysis of isospin-breaking corrections which are of vital importance in the theoretical determination of this observable. The Standard Model prediction, Re(ε0/ε

The onset of spin rotation effects in electroproduction of heavy quarkonia

We discuss the Melosh spin rotation effects in diffractive photo- and electroproduction of heavy quarkonia off a nucleon target in the dipole picture. The quarkonium light-front wave functions are obtained in the Schroedinger equation based formalism using the realistic interquark interaction potentials. A strong onset of spin rotation effects predicted in the case of J/ψ(1S) photoproduction enabl

Heat production rate in polymorphonuclear granulocytes from patients with acute myelogenous leukaemia and healthy individuals

Heat production rate in polymorphonuclear granulocytes (PMN) from 18 AML patients and 21 healthy individuals was measured using microcalorimetry. An increased PMN heat production rate was found in most AML patients at diagnosis and during the first 6 months of remission. In 7/7 patients showing values above the normal mean level the heat production rate decreased during sequential analysis. The in

Complete remission in a patient with acute myelogenous leukemia treated with leukocyte α-interferon and cimetidine

A 76-year-old woman with acute myelogenous leukemia with approximately 65% myeloblasts on bone marrow examination was treated daily with a combination of 4 megaU of leukocyte interferon IM and 1,000 mg cimetidine PO. During therapy there was a gradual decrease of bone marrow myeloblasts down to 9% and a normalization of peripheral white blood cells. The treatment was discontinued after 6 weeks bec

Entrepreneurial Ecosystems in Life Science Industry : A study of start-ups, scale ups and resilience of Entrepreneurial Ecosystems

The Entrepreneurial Ecosystem (EE) literature has presented itself as promising in recent years, as it adopts a systemic network approach on entrepreneurship. Despite its popularity, scholars have also raised some serious concerns, showing it is yet a rather underdeveloped concept. This dissertation addresses some of critiques on the EE literature by proposing four research papers that consist of

On the origin of geometrid moths: the phylogenetic relationships and taxonomy

Geometrid moths represent one of the largest radiations of Lepidoptera. Phylogenetic analyses based on morphological and molecular data supports the monophyly of this group of moths. However, the subfamilial and tribal compositions of major groups are still unresolved, leading to unstable classifications. In this thesis, I investigate the phylogenetic relationships of higher geometrid taxa with th

Development of a real-time quantitative PCR method for detection and quantification of Prevotella copri

Background: Since its discovery in 2007, the importance of the human gut bacterium Prevotella copri (P. copri) has been widely recognized with its links to diet and health status and potential as next generation probiotic. Therefore, precise, convenient and cost-effective diagnostic tools for the detection and quantification of P. copri from clinical and environmental samples are needed. Results:

Evaluation of a training program for life skills education and financial literacy to community health workers in India : a quasi-experimental study

Background: Accredited Social Health Activists (ASHA) are community health workers responsible for improving the health status of people by facilitating their access to healthcare services. The life skills of ASHA are known to be effective in negotiating behaviour change in the community; however, there has been a meagre focus towards improving them. Considering this gap, we adopted a comprehensiv

Probing tissue microstructure by diffusion skewness tensor imaging

Probing the cellular structure of in vivo biological tissue is a fundamental problem in biomedical imaging and medical science. This work introduces an approach for analyzing diffusion magnetic resonance imaging data acquired by the novel tensor-valued encoding technique for characterizing tissue microstructure. Our approach first uses a signal model to estimate the variance and skewness of the di

The spatial RNA integrity number assay for in situ evaluation of transcriptome quality

The RNA integrity number (RIN) is a frequently used quality metric to assess the completeness of rRNA, as a proxy for the corresponding mRNA in a tissue. Current methods operate at bulk resolution and provide a single average estimate for the whole sample. Spatial transcriptomics technologies have emerged and shown their value by placing gene expression into a tissue context, resulting in transcri

Comparison of short-pulse subthreshold (532 nm) and infrared micropulse (810 nm) macular laser for diabetic macular edema

The purpose of the study was to assess both anatomic and functional outcomes between short-pulse continuous wavelength and infrared micropulse lasers in the treatment of DME. This was a prospective interventional study from tertiary care eye hospital—King Khaled Eye Specialist Hospital (Riyadh, Saudi Arabia). Patients with center-involving diabetic macular edema were treated with subthreshold lase

Socio-economic disparities in the dispensation of antibiotics in Sweden 2016–2017: An intersectional analysis of individual heterogeneity and discriminatory accuracy

Aims: Antimicrobial resistance presents an increasingly serious threat to global public health, which is directly related to how antibiotic medication is used in society. Actions aimed towards the optimised use of antibiotics should be implemented on equal terms and according to the needs of the population. Previous research results on differences in antibiotic use between socio-economic and demog

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in women, however, the genetic component underlying this phenomenon is not established. We assess sex-dimorphic (73,089/50,404 women and 67,506/47,806 men) and sex-combined (151,188/

Subacute phase of subarachnoid haemorrhage in female rats : Increased intracranial pressure, vascular changes and impaired sensorimotor function

Objective: Early brain injury (EBI) and delayed cerebral ischemia (DCI) after subarachnoid haemorrhage (SAH) has devastating consequences but therapeutic options and the underlying pathogenesis remain poorly understood despite extensive preclinical and clinical research. One of the drawbacks of most preclinical studies to date is that the mechanisms behind DCI after SAH are studied only in male an

Modeling of exhaust gas cleaning by acid pollutant conversion to aerosol particles

Sulfur and nitrogen oxides (SOx and NOx) are harmful pollutants emitted into the atmosphere by industry and transport sectors. In addition to being hazardous gases, SOx and NOx form sulfuric and nitric acids which contribute to the formation of airborne particulate matter through nucleation and condensation, hence magnifying the environmental impact of these species. In this work, we build a model