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Integrating dissolved and particulate matter into a prediction tool for ozonation of organic micropollutants in wastewater

Ozonation is an established technique used to reduce the discharge of organic micropollutants into the aquatic environment, but the possibility of predicting the ozone demand for different wastewater matrices is still limited, especially in the presence of suspended solids (SS). A new tool for the prediction of the removal of organic micropollutants with ozone, based on dissolved and particulate m

Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain : Structure-based design and optimisation

We have obtained the X-ray crystal structure of the galectin-8 N-terminal domain (galectin-8N) with a previously reported quinoline–galactoside ligand at a resolution of 1.6 Å. Based on this X-ray structure, a collection of galactosides derivatised at O3 with triazole, benzimidazole, benzothiazole, and benzoxazole moieties were designed and synthesised. This led to the discovery of a 3-O-(N-methyl

How to advance theory through literature reviews in logistics and supply chain management

Purpose: The discipline's most common uses for literature reviews—identifying gaps, developing research agendas, and categorizing the literature—too often fail to challenge, change or advance theoretical perspectives. The authors offer guidance to theorization through literature reviews. The key to theory advancement is consistency between the state of theory and the chosen review type. Design/met

Re-interpretation of ‘hummocky moraine’ in the Gaick, Scotland, as erosional remnants : Implications for palaeoglacier dynamics

Many glaciated valleys in Scotland contain distinctive, closely spaced ridges and mounds, which have been termed ‘hummocky moraine’. The ridges and mounds are widely interpreted as ice-marginal moraines, constructed during active retreat of mainly temperate glaciers. However, hummocky terrain can form by various processes in glacial environments, and it may relate to a range of contrasting glaciod

Decision theoretic approach for identification of optimal proof load with sparse resistance information

Proof load testing may be performed to confirm the reliability of the bridge for an existing classification or to prove the reliability for a higher classification.In this paper, a probabilistic decision analysisapproach is applied to the scenario for the evaluation of target proof load in the situation where information on the bridge resistance model is lacking. In this case, the resistance model

Experimental indications of gardeners' anecdotes that snails interfere with invasive slugs

The invasive Spanish slug (Arion vulgaris) is an important pest species in agriculture and horticulture in Europe. In the last decades it has spread across the continent where it outcompetes native slug and snail species, thus posing a threat for biodiversity. A popular anecdote suggests to promote Roman snails (Helix pomatia) in gardens because they are able to control A. vulgaris. We examined a

Microvesicle signaling in cardiovascular biology under normal and pathobiological conditions

Cardiovascular disease (CVD) is one of the leading causes of death worldwide. Atherosclerosis, a chronic pathology directly related to the circulatory system, develops due to an interplay between several molecular events. Atherosclerotic plaque build-up can lead to a reduction in arterial blood flow and finally, myocardial infarction (MI). To prevent or slow down of the CVD progression, it is impo

Association Between Mortality and Levels of Autonomous Cortisol Secretion by Adrenal Incidentalomas : A Cohort Study

BACKGROUND: Autonomous cortisol secretion in patients with adrenal incidentalomas is associated with increased mortality, but detailed information about the risk associated with specific levels of autonomous cortisol secretion is not available.OBJECTIVE: To measure the association between mortality and levels of autonomous cortisol secretion in patients with adrenal incidentalomas.DESIGN: Retrospe

Digitalizing shopping routines: Re-organizing household practices to enable sustainable food provisioning

New digitally enabled modes of food provisioning are being developed. The aim of this paper is to examine, empirically illustrate, and conceptualize how and under what conditions these digital food platforms become routinized and what this means for the enabling of sustainable food consumption.Drawing on an ethnographically inspired study of three digital food provision platforms - i.e. meal box s

A cognitive approach to audio description : production and reception processes

Audio description (AD) provides access to audiovisual materials for people with visual impairments and blindness (BVI) and offers a richer and more detailed understanding and experience. The cognitive approach to AD concerns perceptual, cognitive and meaning-making processes underlying production and reception of AD. By meaning-making, we mean multimodal textual and contextual processing, understaAudio description (AD) provides access to audiovisual materials for people with visual impairments and blindness (BVI) and offers a richer and more detailed understanding and experience. The cognitive approach to AD concerns perceptual, cognitive and meaning-making processes underlying production and reception of AD. By meaning-making, we mean multimodal textual and contextual processing, understa

Audio Description of Art : The Role of Mental Imagery and Embodiment

How can we make visual art accessible for audiences with visual impairment and blindness? Can audio description help blind and visually impaired (BVI) audiences to understand and experience art? Which ingredients must AD contain to evoke and stimulate the creation of vivid internal mental images? Can AD engage the target audiences and contribute to their aesthetic experience and enjoyment? What ot

Bacteriophages fEV-1 and fD1 Infect Yersinia pestis

Bacteriophages vB_YpeM_fEV-1 (fEV-1) and vB_YpeM_fD1 (fD1) were isolated from incoming sewage water samples in Turku, Finland, using Yersinia pestis strains EV76 and KIM D27 as enrichment hosts, respectively. Genomic analysis and transmission electron microscopy established that fEV-1 is a novel type of dwarf myovirus, while fD1 is a T4-like myovirus. The genome sizes are 38 and 167 kb, respective

Streptococcal protein SIC activates monocytes and induces inflammation

Streptococcus pyogenes is a major bacterial pathogen in the human population and isolates of the clinically important M1 serotype secrete protein Streptococcal inhibitor of complement (SIC) known to interfere with human innate immunity. Here we find that SIC from M1 bacteria interacts with TLR2 and CD14 on monocytes leading to the activation of the NF-κB and p38 MAPK pathways and the release of se

Credit Risk in a Pandemic

Using different measures of how the Covid-19 pandemic progresses, the article confirms that the level of credit risk among US blue chip companies increases in tandem with the spread of the Covid-19 virus. The credit risk escalates dramatically during the pandemic but is still short of the levels seen during the 2008–09 Global Financial Crisis. In addition, the weekly ups and downs in credit risk a

Natural selection and the distribution of chromosomal inversion lengths

Chromosomal inversions contribute substantially to genome evolution, yet the processes governing their evolutionary dynamics remain poorly understood. Theory suggests that a readily measurable property of inversions—their length—can potentially affect their evolutionary fates. Emerging data on the lengths of polymorphic and fixed inversions may therefore provide clues to the evolutionary processes