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Simplified citrate anticoagulation for CRRT without calcium replacement.
Since 2012 citrate anticoagulation is the recommended anticoagulation strategy for CRRT. The main drawback using citrate compared with heparin as anticoagulant is the need for calcium replacement and the rigorous control of calcium levels. This study investigated the possibility to achieve anticoagulation while eliminating the need for calcium replacement. This was successfully achieved by includi
Clinically essential requirement for brain CT with iterative reconstruction: author reply.
Four new Caloplaca species (Teloschistaceae, Ascomycotina)
Four new species of the genus Caloplaca, C. kiewkaensis L.S. Yakovczenko, I.A. Galanina & S.Y. Kondr., C. letrouitioides S.Y. Kondr., Elix & Kärnefelt, C. trassii I.A. Galanina & S.Y. Kondr., and C. ussuriensis Oxner, S.Y. Kondr. & Elix from Asia and Australia are described as new to science and compared with closely related species.
Increasing energy coupling into plasma waves by tailoring the laser radial focal spot distribution in a laser wakefield accelerator
By controlling the focal spot quality with a deformable mirror, we are able to show that increasing the fraction of pulse energy contained within the central part of the focal spot, while keeping the total energy and central spot size constant, significantly increases the amount of energy transferred to the wakefield: Our measurements show that the laser loses significantly more laser energy and u
Acute Ultraviolet Radiation Perturbs Epithelialization but not the Biomechanical Strength of Full-thickness Cutaneous Wounds.
We hypothesized that priming of the skin with ultraviolet radiation (UVR) before being injured would enhance wound healing. Four groups, each comprising 20 immunocompetent hairless mice, were exposed to simulated solar irradiation in escalating UVR doses; 0 SED (standard erythema dose) = control, 1 SED, 3 SED and 5 SED. Twenty-four h after UV irradiation, inflammation was quantified by skin reflec
CORTICAL FOLDING PATTERNS AND OBSTETRIC COMPLICATIONS IN SCHIZOPHRENIA
Penile cancer in Scandinavia: Current practice and future perspectives
Absorbed Doses and Risk Estimates of (211)At-MX35 F(ab')2 in Intraperitoneal Therapy of Ovarian Cancer Patients.
Purpose: Ovarian cancer is often diagnosed at an advanced stage with dissemination in the peritoneal cavity. Most patients achieve clinical remission after surgery and chemotherapy, but approximately 70% eventually experience recurrence, usually in the peritoneal cavity. To prevent recurrence, intraperitoneal (i.p.) targeted a therapy has been proposed as an adjuvant treatment for minimal residual
Risk of acute myeloid leukemia and myelodysplastic syndromes after multiple myeloma and its precursor disease (MGUS)
Using population-based data from Sweden, we identified all multiple myeloma (MM) patients (n = 8740) and 5652 monoclonal gammopathy of undetermined significance (MGUS) patients diagnosed between 1986 and 2005. We calculated standardized incidence rates (SIRs) for all subsequent hematologic and nonhematologic malignancies for MM patients diagnosed before/after 1995 (introduction of high-dose melpha
Increased Ethanol Productivity in Xylose-Utilizing Saccharomyces cerevisiae via a Randomly Mutagenized Xylose Reductase
Baker's yeast (Saccharomyces cerevisiae) has been genetically engineered to ferment the pentose sugar xylose present in lignocellulose biomass. One of the reactions controlling the rate of xylose utilization is catalyzed by xylose reductase (XR). In particular, the cofactor specificity of XR is not optimized with respect to the downstream pathway, and the reaction rate is insufficient for high xyl
Many-body interactions between particles in a polydisperse polymer fluid
We use a continuum chain model and develop an analytical theory for the interaction between many spheres immersed in a fluid of ideal polydisperse polymers. Assuming local spherical symmetry of the polymer field about each particle, combined with a local approximation, compact expressions are derived for the many-body interaction between the spheres. We use a mean-field approximation to investigat
Search for a Standard Model Higgs Boson in the H -> ZZ -> l(+)l(-)v(v)over-bar Decay Channel with the ATLAS Detector
A search for a heavy standard model Higgs boson decaying via H -> ZZ -> l(+)l(-)v (v) over bar, where l = e, mu, is presented. It is based on proton-proton collision data at root s = 7 TeV, collected by the ATLAS experiment at the LHC in the first half of 2011 and corresponding to an integrated luminosity of 1.04 fb(-1). The data are compared to the expected standard model backgrounds. The data an
Precise U-Pb baddeleyite age dating of the Usushwana Complex, southern Africa - Implications for the Mesoarchaean magmatic and sedimentological evolution of the Pongola Supergroup, Kaapvaal Craton
The Usushwana Complex of the south-eastern Kaapvaal Craton (South Africa and Swaziland), intrudes the ca. 3.6-3.1 Ga basement of the craton, as well as the Mesoarchaean volcanic and sedimentary cover succession of the Pongola Supergroup. New high-precision U-Pb dating of gabbros belonging to the Piet Retief Suite of the Usushwana Complex yield ages of 2989 +/- 1 Ma, 2990 +/- 2 Ma and 2978 +/- 2 Ma
Relationships between tissue composition and viscoelastic properties in human trabecular bone.
Trabecular bone is a metabolically active tissue with a high surface to volume ratio. It exhibits viscoelastic properties that may change during aging. Changes in bone properties due to altered metabolism are sensitively revealed in trabecular bone. However, the relationships between material composition and viscoelastic properties of bone, and their changes during aging have not yet been elucidat
A Digitally Assisted Non-Linearity Mitigation System for Tunable Channel Select Filters
This brief presents a low-complexity system for digitally assisting a channel select filter (CSF) to mitigate both even- and odd-order nonlinearities. The proposed solution is scalable and can be utilized for nonlinearity mitigation in different analog transceiver blocks. The system consists of an auxiliary path with a low-resolution analog to digital converter (ADC) enabling digital recreation an
Health care costs attributable to overweight calculated in a standardized way for three European countries.
This article presents a tool to calculate health care costs attributable to overweight in a comparable and standardized way. The purpose is to describe the methodological principles of the tool and to put it into use by calculating and comparing the costs attributable to overweight for The Netherlands, Germany and Czech Republic. The tool uses a top-down and prevalence-based approach, consisting o
Familial Association of Inflammatory Bowel Diseases With Other Autoimmune and Related Diseases
OBJECTIVES: Familial risk estimates are useful for genetic counseling, etiological understanding, and design of gene identification studies. We wanted to estimate the associations of ulcerative colitis (UC) and Crohn's disease (CD) with 32 autoimmune and related diseases among parents and offspring, singleton siblings, twins, and spouses. METHODS: The Multigeneration Register in Sweden provides re
Retinal functional alterations in mice lacking intermediate filament proteins glial fibrillary acidic protein and vimentin.
Vimentin (Vim) and glial fibrillary acidic protein (GFAP) are important components of the intermediate filament (IF) (or nanofilament) system of astroglial cells. We conducted full-field electroretinogram (ERG) recordings and found that whereas photoreceptor responses (a-wave) were normal in uninjured GFAP(-/-)Vim(-/-) mice, b-wave amplitudes were increased. Moreover, we found that Kir (inward rec