The outer membrane protein A (OmpA) family contains an evolutionary conserved domain that links the outer membrane in Gram-negative bacteria to the semi-rigid peptidoglycan (PG) layer. The clinically significant pathogen Pseudomonas aeruginosa carries several OmpA family proteins (OprF, OprL, PA0833, and PA1048) that share the PG-binding domain. These proteins are important for cell morphology, me

INTRODUCTION: Radiographers' engagement in research is important for the development of evidence-based practice in radiography; however, radiographers' interest in research has rarely been reported. This study sought to ascertain radiographers' opinions about radiography research and investigate their involvement in research activities in four Nordic countries.METHODS: This study was conducted in

Wing integrity is crucial to the many insect species that spend distinct portions of their life in flight. How insects cope with the consequences of wing damage is therefore a central question when studying how robust flight performance is possible with such fragile chitinous wings. It has been shown in a variety of insect species that the loss in lift-force production resulting from wing damage i

På uppdrag av Naturvårdsverket har avdelningen för Arbets- och miljömedicin vid Lunds Universitet utfört studie kring luftföroreningssituationen på förskolegårdar.Denna studie består av tre delar vara av en är en kunskapsinventering bland landets kommuner kring luftkvalitén på förskolebarns utemiljöer och effekter/strategier för att eventuellt förbättra detta. (sedan tidigare publicerad i denna ra

Anemia is common in critically ill patients. Some patients benefit from erythrocyte transfusion, but transfusions are also associated with complications. Randomized controlled trials in critically ill patients have demonstrated that a restrictive transfusion strategy seems safe. This review is an overview of some of the largest studies of erythrocyte transfusions in intensive care.

BackgroundChildren with ADHD tend to present with poorer cognitive functioning leaving them more vulnerable to a range of negative outcomes. To date, only a handful of longitudinal studies have examined the stability of Wechsler composite scores in children and adolescents with ADHD, and none of them used a more recent version of the Wechsler Intelligence Scales for Children (WISC), than the WISC-

This article focuses on debunking assumptions surrounding the use of balancing and proportionality in international investment arbitration as a way of successfully reconciling competing interests and conflicting protection obligations vested upon host states.

Olika typer av sinnesförändrande substanser har blivit allt fler och vanligare under de senaste 500 åren, och användningen i nutidens konsumtionskulturer fortsätter att öka. Den illegala droganvändningen i Sverige ligger på historiskt höga nivåer. Vissa lagliga preparat, såsom kaffe och alkohol, syns överallt medan läkemedel och illegala droger vanligtvis hålls dolda. Denna etnologiska avhandling

Focal non-convulsive status epilepticus (fNCSE) is a neurological condition characterized by a prolonged seizure that may lead to the development of epilepsy. Emerging experimental evidence implicates neuronal death, microglial activation and alterations in the excitatory and inhibitory synaptic balance as key features in the pathophysiology following fNCSE. We have previously reported alterations

The Homogeneous Charge Compression Ignition (HCCI) combustion progress has been characterized by means of high- speed fuel tracer Planar Laser-Induced Fluorescence (PLIF) combined with simultaneous chemiluminescence imaging. Imaging has been conducted using a high-speed laser and detector system. The system can acquire a sequence of eight images within less than one crank angle. The engine was run

Extensive diversity has been identified in the human heavy chain immunoglobulin locus, including allelic variation, gene duplication, and insertion/deletion events. Several genes have been suggested to be deleted in many haplotypes. Such findings have commonly been based on inference of the germline repertoire from data sets covering antibody heavy chain encoding transcripts. The inference process

Cell-free DNA (cfDNA) is the major structural component of neutrophil extracellular traps (NETs), an innate immune response to infection. Antimicrobial proteins and peptides bound to cfDNA play a critical role in the bactericidal property of NETs. Recent studies have shown that NETs have procoagulant activity, wherein cfDNA triggers thrombin generation through activation of the intrinsic pathway o

Lenalidomide, an antineoplastic and immunomodulatory drug, has therapeutic activity in acute myeloid leukemia (AML), but definitive studies about its therapeutic utility have been lacking. In a phase 3 study, we compared 2 induction regimens in newly diagnosed patients age 18 to 65 years with AML: Idarubicine-cytarabine (cycle 1) and daunorubicin and intermediate-dose cytarabine (cycle 2)without o

An important manifestation of severe COVID-19 is the ARDS-like lung injury that is associated with vascular endothelialitis, thrombosis, and angiogenesis. The intravascular innate immune system (IIIS), including the complement, contact, coagulation, and fibrinolysis systems, which is crucial for recognizing and eliminating microorganisms and debris in the body, is likely to be involved in the path