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Tumor hypoxia is associated with several features of aggressive glioma growth, including migration, invasion, and stemness. Most of the cellular adaptation to hypoxia is mediated by the hypoxia-inducible factors HIF-1α and HIF-2α, but regulation of these factors by both oxygen-dependent and –independent mechanisms in brain tumors is only partially understood. Here, we show that the p75 neurotrophi
Parasites can vary in the number of host species they infect, a trait known as “host specificity”. Here we quantify phylogenetic signal—the tendency for closely related species to resemble each other more than distantly related species—in host specificity of avian haemosporidian parasites (genera Plasmodium, Haemoproteus and Leucocytozoon) using data from MalAvi, the global avian haemosporidian da
Estimating the parameters of non-uniformly sampled multi-dimensional damped modes is computationally cumbersome, especially if the model order of the signal is not assumed to be known a priori. In this work, we examine the possibility of using the recently introduced wideband dictionary framework to formulate a computationally efficient estimator that iteratively refines the estimates of the candi
We demonstrate range-resolved detection of atomic hydrogen in methane/oxygen flames based on 2-photon excited backward lasing using 205-nm femtosecond laser pulses. Range resolution is achieved by temporally resolving the backward emission with a streak camera.
The area of immobilized cells and organelles has expanded very fast. Many new techniques for the preparation of immobilized cells have been developed during the last decade, especially during the last 5 years. Concomitantly with this availability of methods for obtaining suitable preparations, a rather broad spectrum of applications have been investigated. The preparations used have been based on
For the first time, to the best of the authors' knowledge, nonintrusive quantitative measurement of hydrogen cyanide (HCN) released during the devolatilization phase of straw pellets gasification is demonstrated with high spatial and temporal resolution. Mid-infrared degenerate four-wave mixing (IR-DFWM) measurements of HCN were performed by probing the interference-free P(20) line in the v 1 vibr
In experimental studies, eosinophils have been shown to promote the survival, proliferation, and retention of plasma cells in the bone marrow (BM). The clinical significance of eosinophils in plasma cell disorders (PCDs) in humans is largely unknown. This study focuses on the frequency and phenotype of eosinophils in the BM and peripheral blood (PB) in patients with untreated PCD compared with hea
Birds, particularly raptors, are believed to forage primarily using visual cues. However, raptor foraging tactics are highly diverse – from chasing mobile prey to scavenging – which may reflect adaptations of their visual systems. To investigate this, we studied the visual field configuration of 15 species of diurnal Accipitriformes that differ in such tactics, first focusing on the binocular fiel
Background: Non-motor symptoms (NMS) are common in late stage Parkinson's disease (PD), as the frequency and severity of most of these symptoms increase with advancing disease. Objective: To assess effect of dopaminergic therapy on NMS in late stage PD and to investigate relationships between dopaminergic effect on NMS and on motor function. Method: Thirty PD patients in Hoehn and Yahr (HY) stages
Objectives: The aims of this study are (1) to compare dual-energy X-ray absorptiometry (DEXA) and bioimpedance for body composition measurements in nondialysis patients with chronic kidney disease, and (2) to investigate factors associated with any measurement differences. Design and Methods: This is a substudy using some baseline data from a randomized controlled clinical trial. One hundred twent
Medan den götiska romantiken ville lägga det isländska arvet till grund för den svenskspråkiga nationallitteraturen, författade Carl Georg Brunius en stor dikt om de nordiska gudarna på latin (1822). Denna artikel undersöker dikten och dess mottagande utifrån motsättningen mellan latindiktningens kosmopolitiska karaktär och den frambrytande nationallitterära ordningen. Brunius’ senkommenhet, som n
Governments of different levels have been implementing various policies to enhance the closure of material loops, as well as to reduce the risk of hazardous substances. Manufacturers and distributors of products have a crucial role in the selection and/or verification of materials for their new products. This study sought to obtain concrete knowledge on perception, experiences, and future outlook
Animal signals involved in sexual selection are often indicators of individual quality. The assumption that sexual characters such as breeding plumage may indicate immune state has rarely been tested in free-living migratory birds, particularly in relation to innate immunity. If sexual characters indeed reflect immune condition, then these could be used to evaluate individual quality. Melanin is a
This paper summarizes the development and application of degenerate four-wave mixing (DFWM), polarization spectroscopy (PS) and laser-induced thermal grating spectroscopy (LITGS) in the mid-infrared spectral region for combustion diagnostics over the last decade.
Background: Effective digestive enzymes are crucial for successful islet isolation. Supplemental proteases are essential because they synergize with collagenase for effective pancreatic digestion. The activity of these enzymes is critically dependent on the presence of Ca2+ ions at a concentration of 5–10 mM. The present study aimed to determine the Ca2+ concentration during human islet isolation
On the base of reaction of deuteron photo-disintegration it was studied possibility of the simultaneous measuring of cross sections and asymmetry of the (γ,p) reactions at the using of the coherent polarized photon beam. Measurements were performed for the proton emission angle 90°. The cross sections well agree with the literary data, obtained on the bremsstrahlung photon beam in the range of ene
Background and Policy Context: Previous chapters in this book have explored several product-oriented policies, including mandatory laws and product energy labelling, and discussed the importance of an appropriate policy mix. In this chapter, we examine the effects of demand-side policies, with a focus on green public procurement (GPP). GPP has been defined as ‘a process whereby public authorities
I detta temanummer av Förvaltningsrättslig tidskrift har vi samlat bidrag som analyserar 2017 års FL från fyra perspektiv: nyheter i förvaltningslagen, uppdateringar i förvaltningslagen, utanför förvaltningslagen och förvaltningslagen och dess förhållande till andra lagar. Temanumret avslutas med en internationell utblick.
