The normal role of Alzheimer's disease (AD)-linked amyloid precursor protein (APP) in the brain remains incompletely understood. Previous studies have reported that lack of APP has detrimental effects on spines and electrophysiological parameters. APP has been described to be important in synaptic pruning during development. The effect of APP knockout on mature synapses is complicated by this role

This article argues that the type of individualized social media activism that has been conceptualized as ‘connective action’ has affinities to populism, and may have detrimental consequences for democratic procedures and the bureaucratic structures that enable them. We trace the normative allure of individualized digital engagement to the libertarian roots of techno-utopianism and argue that this

Community energy (CE) and grassroots innovations have been widely studied in recent years, especially in the UK, Germany, and the Netherlands, but very little focus has been placed on Sweden. This paper describes and analyses the development and present state of several types of community energy initiatives in Sweden. The methodology uses interviews, document studies, analysis of previous studies,

Tau neuronal and glial pathologies drive the clinical presentation of Alzheimer's disease and related human tauopathies. There is a growing body of evidence indicating that pathological tau species can travel from cell to cell and spread the pathology through the brain. Throughout the last decade, physiological and pathological tau have become attractive targets for AD therapies. Several therapeut

Recension av Hästbacka, Europeiska företagsråd.

Ofta används uttrycket 'får jag låna...' utan att riktigt att ha en tanke på att lämna tillbaks saltkornen, toaletten eller tändstickan. Bidraget diskuterar vad som upplevs som oproblematiskt att låna, och vilka förfrågningar som kan orsaka starka känslor.

Planekonomi kommer aldrig att kunna lösa klimatproblemen. Statens roll i att bidra till en klimatomställning handlar enbart om att skapa incitament för marknaden att lösa problemen. ”Lösningar” som beskattning av utsläpp är inte relevanta förrän marknaden kan erbjuda verkliga alternativ till fossila bränslen.

AIMS: There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after 'recalibration', a method that adapts risk algorithms to take account of differences in the risk characteristics of the populations being studied. METHODS AND RESULTS: Using indivi

Antologin består av bidrag från tio forskare relaterade till forskarseminariet i missionsvetenskap med ekumenik i Lund. Alla har de gemensamt att de intresserat sig för religioners gränsöverskridanden och mötet med andra religioner och /eller kulturer, att de studerat interaktiviteten i de gränsöverskridande processerna och, likt etnografen, tecknat ner sina observationer och sina tolkningar.

Hur ser den demokratiska fasaden ut och vilket politisk makt de politiska partierna har?