On June 13, 2013, the U.S. Supreme Court decided the Myriad gene patent case. In a unanimous judgment the Court held that patent claims directed to isolated genomic DNA are identical to the naturally occurring sequence and thus unpatentable “products of nature”. This decision affects all isolated"products of nature", including genes, gene fragments, and other naturally occurring nucleotide sequenc

This article explores relevant laws and doctrines of patent infringement in Europe with a special emphasis on 3D printing (3DP) technologies. Considering the difficulties that patent owners might face in pursuing direct patent infringement actions in the rapidly evolving era of 3DP, we suggest that patent owners will most likely direct their efforts towards indirect patent infringement strategies.

It is fair to assume that the process of standardization may have a significant impact on the development and adoption of SB. Within SB different standardization efforts have been made, but none has assumed a dominance or authority in the area. Standardization efforts within SB may differ within various technical areas, and also the basic processes of standard creation can be divided into various

The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and expert consultants in the field, this update is based on a systematic review of the literature centred on the following: the Population (P), Intervention (I), Co

Urban water systems and, in particular, wastewater treatment facilities are among the major energy consumers at municipal level worldwide. Estimates indicate that on average these facilities alone may require about 1% to 3% of the total electric energy output of a country, representing a significant fraction of municipal energy bills. Specific power consumption of state-of-the-art facilities shoul

Background: Umbilical and epigastric hernia repairs are frequently performed surgical procedures with an expected low complication rate. Nevertheless, the optimal method of repair with best short- and long-term outcomes remains debatable. The aim was to develop guidelines for the treatment of umbilical and epigastric hernias. Methods: The guideline group consisted of surgeons from Europe and North

Current large-scale deforestation poses a threat to ecosystems globally, and imposes substantial and prolonged changes on the hydrological and carbon cycles. The tropical forests of the Amazon and Indonesia are currently undergoing deforestation with catastrophic ecological consequences but widespread deforestation events have occurred several times in Earth's history and these provide lessons for

Artikel om den amerikanska historiens betydelse som politisk kraft.

This book discusses in detail how Orthodox Christianity was involved in and influenced political transition in Ukraine, Serbia, and Georgia after the collapse of communism. Based on original research, including extensive interviews with clergy and parishioners as well as historical, legal, and policy analysis, the book argues that the nature of the involvement of churches in post-communist politic

Perovskite solar cells are among the most exciting photovoltaic systems as they combine low recombination losses, ease of fabrication, and high spectral tunability. The Achilles heel of this technology is the device stability due to the ionic nature of the perovskite crystal, rendering it highly hygroscopic, and the extensive diffusion of ions especially at increased temperatures. Herein, we demon

This paper deals with the real-time implementation of feedback controllers. In particular, it provides an analysis of the stability property of closed-loop systems that include a controller that can sporadically miss deadlines. In this context, the weakly hard m-K computational model has been widely adopted and researchers used it to design and verify controllers that are robust to deadline misses

The article is a comparative inquiry into the roles of Ilia Chavchavadze (1837-1907) and Taras Shevchenko (1818-1861) as national poets and anti-tsarist intellectuals within the context of their respective national traditions (in Georgia and Ukraine). During the period of their activity (19th and the beginning of 20th century), both Ukraine and Georgia were under tsarist imperial rule (albeit the

Since the Rose Revolution (2003), Georgia has encountered an unprecedented scale of institutional reforms concomitant with the rise of American and European involvement in the “democratization” process. Various scholars have suggested that Georgian nationalism developed from an ethno-cultural basis to a more civic/liberal orientation after the Rose Revolution. This paper analyzes Georgian national

In their natural environments, organisms are unlikely to be distributed randomly but instead they are constantly faced with multiple and variable threats. In order to maximise survival, they need to be able to perceive the present threat level and respond accordingly. In aquatic ecosystems, two common threats for crustacean zooplankton are predation and ultraviolet radiation (UVR). Despite the gro

Purpose of ReviewIt is important to examine what effect sleep has after an emotional experience. More knowledge about this topic could help inform us whether there are any potential sleep interventions that could help make sure that memories of negative emotional experiences are processed in the most adaptive manner possible.Recent FindingsFindings on the role of sleep in altering reactivity to em

The Learning with Errors (LWE) problem is one of the main mathematical foundations of post-quantum cryptography. One of the main groups of algorithms for solving LWE is the Blum-Kalai-Wasserman (BKW) algorithm. This paper presents new improvements for BKW-style algorithms for solving LWE instances. We target minimum concrete complexity and we introduce a new reduction step where we partially reduc