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To continue the development of novel therapeutics to treat bladder cancer, a reliable model for preclinical testing of treatments and studying of the disease mechanism is essential. Ex vivo culturing of precision cut tumor slices (PCTS) provides a model that can retain the tumor architecture and its tumor microenvironment including the immune cell compartment, but data on PCTS based on bladder tum

The historically rapid growth of modern cities has a tearing effect on our planet, which requires a systematic transformation from linear to circular resource usage and consumption. Scientists and decision makers world-wide propose Circular Cities as a part of the solution, but empirical evidence and theoretical models of their practical implementation is lacking. This study explores the framework

Punktlighet och förseningar inom järnväg är något som står högt upp på agendan i dagens samhälle. Med en infrastruktur som är i ett stort behov av underhåll samtidigt som trycket på klimatsmarta transportlösningar bara ökar, blir punktligheten och framkomligheten inom järnvägen avgörande. Med en total punktlighet på ungefär 90% finns det mycket att göra. En av järnvägens infrastrukturproblem är spPunctuality and delays within the railway system are of utmost concern in today’s society. With an infrastructure in a dire need of maintenance and the increasing pressure for environmentally friendly transportation solutions, punctuality and accessibility within the railway system becomes crucial. With an overall punctuality rate of approximately 90%, there is much to be improved. One of the prob

Dagens slit och slängsamhälle är inte hållbar, och en övergång till en mer cirkulär ekonomi där produkter bland annat, underhålls och repareras för att produkter ska ha en hög kvalité och värde en längre tid är nödvändig. I de flesta fall är det bättre att reparera en produkt än att ersätta den, då det krävs mindre råmaterial, genererar mindre växthusgasutsläpp samt har mindre påverkan på ekosysteTo meet climate objectives our society needs to be more resource efficient, and a circular economy is part of the solution. Maintaining and repairing products to prolong their lifetime is usually better than replacing the product. In Sweden there are existing economic policies such as value added tax and tax reductions that incentivize the consumer towards prolonging the life of their products, bu

Bloodstream infections (BSIs) are among the top causes of death in Europe and as such, a serious health concern. Blood cultures are the most common method to diagnose this condition, bringing certain disadvantages. Mainly, it is time- consuming as it can take several days to get the test results back. Furthermore, the blood cultures carry a high risk of contamination. For this reason, a successful

Forskningsfråga: Vilka faktorer bidrar till att influencerskapade företag inom den svenska modebranschen kan ta ut en prispremie? Syfte: Analysera vilka faktorer som påverkar influencerstartade företags prispremier och varumärkesstyrka, samt bidra med vägledning och verktyg till företag som är aktiva digitalt. Metod: Studien är en fallstudie som antar en deduktiv ansats med en kvalitativ metod. Research question: What factors contribute to influencer-created companies in the Swedish fashion industry being able to charge a price premium? Purpose: Analyze the factors that influence the price premiums and brand equity of influencer-started companies, as well as provide guidance and tools for companies that are active digitally. Methodology: The study is a case study adopting a deductive a

The Belt and Road Initiative (BRI), spearheaded by China, represents a transformative global infrastructure and economic development strategy. This thesis investigates the intricate ramifications of the BRI in East Africa, with a focus on Kenya's and Tanzania's strategic engagements. Adopting a qualitative exploratory approach grounded in secondary data sources, the study examines how thes

Objective: Mental health is a key concern among refugees, yet treatment response to standardized interventions varies. Functioning is a clinically significant outcome that has been shown to explain individual differences in treatment response. The current study examined functional impairment among trauma-exposed refugees receiving treatment in Denmark. It explored the relationship of various pre-

This study explores the intricate dynamics and factors driving consumer engagement in online activism and boycotts, shedding light on the complex interplay between personal values, socioeconomic status, and social networks. Drawing upon and utilizing theories from other researchers, this study examines the impact of economic, social, and cultural factors that drive consumers to engage in online ac

Amelogenin, a critical protein in enamel formation, self-assembles into supramolecular structure that guide hydroxyapatite (HAP) crystal growth that is essential for the development of strong and healthy enamel. Phosphorylation of amelogenin at Ser-16 plays a pivotal role in modulating its self-assembly and functional properties, impacting the overall enamel biomineralization process. This post-tr

Machine learning has been growing in popularity for many years now and is currently popular among both businesses and private individuals. Running machine learning models takes a lot of computational resources, which means a large amount of energy is consumed. The aim of this thesis is to investigate the usage of machine learning model specific hardware on Field Programmable Gate Arrays (FPGAs) a

Antibiotic resistance is a global concern and is promoted by various types of bacterial efflux systems. One known efflux system expressed by the Acinetobacter genus is the chromosomally encoded AdeABC pump which works in conjunction with the regulatory system AdeRS. Recently, plasmid encoded variants of the adeRS and adeABC have been identified and it is thought that these may pose similar or high

Den tekniska utvecklingen tillåter företagen att implementera nya lösningar i sina verksamheter, men den låter även cyberangripare utveckla nya metoder för att angripa företagen. En rad olika metoder bygger på att lura den enskilda anställda i företaget att dela känsliga data med angriparen utan att de själva vet om det. Människan har även beskrivits som den “svaga länken” i cybersäkerhet, efterso

Entrepreneurship is essential to accelerate entrepreneurial innovation and economic growth. Brilliant ideas do not only arise from the Eureka moment but the founder's talent and creativity have a large cooperation in this process. There are many factors that trigger the founder's creativity and can lead to successful entrepreneurship. This paper aims to study the relationship between the c

This thesis examines post-acquisition resistance and its implications for post-merger integration (PMI) following hostile takeovers as this presents distinctive and intricate challenges within organizational change dynamics. Through a qualitative case study approach, this research investigates the interactions between a leading private equity firm, "Alpha", and a major multinational manu

This study examines how three different methods for addressing cross-sectional dependency can affect the regression results. By ignoring the problem, using a two-way fixed effects model and using Common Correlated Effects (CCE), three regressions are run to answer the research question. In order to conduct this analysis, a growth model is specified and consists of the following explanatory variabl

This paper aims to investigate the policies in two documents from the National Board of Social Affairs and Health regarding healthcare for transgender youth and people with intersex variations. Using Bacchis method of analysis ”What's the problem represented to be?” as well as Michel Foucault's theory of biopower and Judith Butler’s theory of the heterosexual matrix, we examined the assump

The current work aims to investigate the impact of angular momentum in galaxy formation especially in the coevolution of the stellar central density (Σ⋆,1.2kpc) and total stellar mass (M⋆). This is achieved by tracing the histories of three simulated halos where the specific angular momentum is altered by modifying the initial conditions of the Lagrangian patch of baryons. The analysis consists of

Individers förhållningssätt och tillfredsställelse rörande sin sexualitet har visat sig hänga nära samman med upplevt mående och hälsa. Äldre kvinnors upplevelse av sin sexualitet är ett relativt outforskat område, speciellt i en svensk kontext. Mot bakgrund av detta var syftet med denna studie att skapa en fördjupad förståelse och kunskap kring 65-80 åriga kvinnors upplevelse av sexualitet och seIndividuals' attitudes and satisfaction regarding their sexuality have been shown to be closely related to perceived well-being and health. Older women's experience of their sexuality is a relatively unexplored area, especially in a Swedish context. In light of this, the aim of this study was to create a deeper understanding and knowledge of 65-80 year old women's experience of sexuali