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Prime Locations

We harness big data to detect prime locations---large clusters of know-ledge-based tradable services---in 125 global cities and track changes in the within-city geography of prime service jobs over a century. Historically smaller cities that did not develop early public transit networks are less concentrated today and have prime locations farther away from their historic cores. We rationalize thes

Rapport 11 från Taxonomikommittén

Här presenteras de senaste besluten av BirdLife Sveriges Taxonomi­ kommitté. Detta är en förkortad version, den fullständiga rapporten med mer detaljer, referenser och extralimitala förändringar finns på Tk:s hemsida under ”Rapporter”. I denna omgång utökas inte Sverigelistan med nya arter, dock urskiljs ett antal som mycket väl kan uppträda i Sverige i framtiden. Flera välkända svenska häckfåglar

Transformation of the Ghent system in Sweden: Silent Institutionalization of Complementary Unemployment Benefits

The Swedish public unemployment insurance program is characterized by its governance structure involving union-linked insurance funds, famously known as the Ghent system. This paper argues that the unions’ strongly entrenched interest in the provision of unemployment benefits has continued to shape the establishment and expansion of complementary benefits for the unemployed in multiple forms, incl

More Power to the People: Electriciy Adoption, Technological Change and Labour Conflict

Will technical change spur conflicts in the labor market? In this study, we examine electricity adoption in Sweden during the first decades of the twentieth century. Exploiting that proximity to hydropowered plants shaped the electricity network independently of previous local conditions, we estimate the impact of electricity on labor strikes. Our results indicate that electricity adoption precede

Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer's disease

In Alzheimer's disease (AD), the Braak staging scheme suggests a stereotypical tau spreading pattern that does, however, not capture interindividual variability in tau deposition. This complicates the prediction of tau spreading, which may become critical for defining individualized tau-PET readouts in clinical trials. Since tau is assumed to spread throughout connected regions, we used functional

A facile one-stage treatment of critical bone defects using a calcium sulfate/hydroxyapatite biomaterial providing spatiotemporal delivery of bone morphogenic protein-2 and zoledronic acid

Bone morphogenic proteins (BMPs) are the only true osteoinductive molecules. Despite being tremendously potent, their clinical use has been limited for reasons including supraphysiological doses, suboptimal delivery systems, and the pro-osteoclast effect of BMPs. Efforts to achieve spatially controlled bone formation using BMPs are being made. We demonstrate that a carrier consisting of a powder o

Solubility and Thermal Degradation of Quercetin in CO2-Expanded Liquids

The solubility of quercetin and its thermal degradation was studied in CO2-expanded ethanol and ethyl lactate. An equipment setup was constructed that enabled the separation of the products of degradation while quantifying the solubility of quercetin. Three different conditions of temperature were analyzed (308, 323, and 343 K) at 10 MPa. Higher solubility and thermal degradation of quercetin were

Effects of simulated drought on biological soil quality, microbial diversity and yields under long-term conventional and organic agriculture

Drought and agricultural management influence soil microorganisms with unknown consequences for the functioning of agroecosystems. We simulated drought periods in organic (biodynamic) and conventional wheat fields and monitored effects on soil water content, microorganisms and crops. Above the wilting point, water content and microbial respiration were higher under biodynamic than conventional far

Patients' aged ≥65 years dispositions during ambulance assignments, including factors associated with non-conveyance to hospital : A longitudinal and comparative study

Objectives Patients ≥65 years old represent 30%-50% of all ambulance assignments (AAs), and the knowledge of which care level they are disposed to is limited and diverging. The aim of this study was therefore to describe and compare characteristics of patients' aged ≥65 years dispositions during AA, including determining changes over time and factors associated with non-conveyance to hospitals. De

Subdominance in Antibody Responses : Implications for Vaccine Development

SUMMARYVaccines work primarily by eliciting antibodies, even when recovery from natural infection depends on cellular immunity. Large efforts have therefore been made to identify microbial antigens that elicit protective antibodies, but these endeavors have encountered major difficulties, as witnessed by the lack of vaccines against many pathogens. This review summarizes accumulating evidence that

Selection on phenotypic plasticity favors thermal canalization

Climate change affects organisms worldwide with profound ecological and evolutionary consequences, often increasing population extinction risk. Climatic factors can increase the strength, variability, or direction of natural selection on phenotypic traits, potentially driving adaptive evolution. Phenotypic plasticity in relation to temperature can allow organisms to maintain fitness in response to

Trade-offs in absorption and scattering by nanophotonic structures

Trade-offs between absorption and scattering cross sections of lossy obstacles confined to an arbitrarily shaped volume are formulated as a multi-objective optimization problem solvable by Lagrangian-dual methods. Solutions to this optimization problem yield a Pareto-optimal set, the shape of which reveals the feasibility of achieving simultaneously extremal absorption and scattering. Two forms of

Impaired cerebral oxygenation in heart failure patients at rest and during head-up tilt testing

AIMS: Heart failure (HF) confers potentially negative effects on the brain and autonomic nervous system. The measurement cerebral tissue oxygen saturation (SctO2 ) may aid in understanding such effects. We aimed to investigate if compensated HF affects SctO2 at rest and during orthostatic challenge.METHODS AND RESULTS: Non-invasive haemodynamic monitoring and near-infrared spectroscopy were applie