Huntington's disease (HD) is a severe, genetic brain disorder that causes great suffering and leads to an early death. The medical research team in the project Treatments of the Future at Lund University aims to develop a new molecular gene therapeutic method that will give the possibility to cure the disease. The authors’, social- and cultural scientists, mission is to develop recommendations for

This chapter compares active inclusion strategies in five European cities with high problem pressure. The focus is on minimum income protection with particular attention paid to social assistance as well as to activation policies and the role of the third-sector in providing support and services. The local active inclusion strategies studied diverge substantially regarding the level of market-orie

Background A 1-h algorithm based on high-sensitivity cardiac troponin T (hs-cTnT) testing at presentation and again 1 h thereafter has been shown to accurately rule out acute myocardial infarction. Objectives The goal of the study was to evaluate the diagnostic accuracy of the 1-h algorithm when supplemented with patient history and an electrocardiogram (ECG) (the extended algorithm) for predicti

The rapid advances in life science, including the sequencing of the human genome and numerous other techiques, has given an extraordinary ability to aquire data on biological systems and human disease. Even so, drug development costs are higher than ever, while the rate of new approved treatments is historically low. A potential explanation to this discrepancy might be the difficulty of understand

A significant part of the cost of a construction project, up to 90%, consists of purchased goods and services. Suppliers thereby have a large impact on the quality, price and time of projects. Purchasing management is therefore important for the outcome of a project. The aim of research covered by this thesis is to describe and analyse purchasing management and its interrelation with the supplier

Recension av Gerald Leonard Cohen, Origin of the Term "Jazz" (Rolla, MO: Missouri University of Science & Technology, 2016).

During the last two decades or so, film support, film policy and the public financing of audiovisual production in Scandinavia and particularly Sweden have undergone extensive transformation. In diverse ways, these changes can be seen as responses to globalization, to increased sub-national regional independence as well as to the emerging idea of nurturing ‘creative industries’ taking hold. They m

This study introduces a corpus of 260 naturalistic human nonlinguistic vocalizations representing nine emotions: amusement, anger, disgust, effort, fear, joy, pain, pleasure, and sadness. The recognition accuracy in a rating task varied greatly per emotion, from 70% for amusement, pleasure, fear, and sadness. In contrast, the raters’ linguistic–cultural group had no effect on recognition accuracy:

The overall aim of this thesis is to examine how walking as a transport mode is constructed in the planning realm, affected by the built environment and perceived by the individual. This aim is related to the following research questions: (1) How are pedestrians and walking understood, constructed and perceived in the planning context? (2) How does individual traits and the built environment affec

Purchasing on the part of a building construction company involves actors inside and outside the organization. These actors are driven by different motives that influence purchasing decisions in different situations. An explicit framework that assists in understanding the different purchasing situations would be of benefit to companies and researchers. Through a study of purchasing theory and pracPurchasing on the part of a building construction company involves actors inside and outside the organization. These actors are driven by different motives that influence purchasing decisions in different situations. An explicit framework that assists in understanding the different purchasing situations would be of benefit to companies and researchers. Through a study of purchasing theory and prac

All animals and some bacteria can synthesize linear polysaccharides with a backbone of repeating disaccharideunits, called glycosaminoglycans (GAGs). The GAGs are either attached to a protein core, as in proteoglycans (PGs), or exist as free polymer chains, as in hyaluronan. One of the most common types of GAGs is chondroitin/dermatan sulfate (CS/DS), where the repeating disaccharide backbone consAll animals and some bacteria can synthesize linear polysaccharides with a backbone of repeating disaccharideunits, called glycosaminoglycans (GAGs). The GAGs are either attached to a protein core, as in proteoglycans (PGs), or exist as free polymer chains, as in hyaluronan. One of the most common types of GAGs is chondroitin/dermatan sulfate (CS/DS), where the repeating disaccharide backbone cons